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Additional pathologic findings included: chronic peptic duodenitis (6 out of 17, 35%), active duodenitis (1 out of 17, 6%), and celiac-like features (2 out of 17, 12%) in the duodenum; chemical gastropathy (3 out of 18, 17%), active chronic gastritis without Helicobacter pylori (2 out of 18, 11%), and erosion (1/18,6%) in the stomach; reactive epithelial change (3 out of 7, 43%), active esophagitis (3 out of 7, 43%), ulceration (2 out of 7, 29%), and erosion (1 out of 7, 14%) in the esophagus. Serum MPA levels were available in 7 patients, 6 of whom had abnormal duodenal apoptotic counts.

其他病理特点包括:十二指肠:慢性消化性十二指肠炎(17例中有6例,35%)、活动性十二指肠炎(17例中有1例,6%)和乳糜泻样特征(17例中有2例,12%);胃:化学性胃病(18例中有3例,17%)、慢性活动性胃炎且无HP感染(18例中有2例,11%)和糜烂(18例中有1例,6%);食管活检:反应性上皮改变(7例中有3例,43%)、活动性食管炎(7例中有3例,43%)、溃疡(7例中有2例,29%)和糜烂(7例中有1例,14%)。7例患者提供了其血清MPA浓度,其中有6例的十二指肠细胞凋亡计数异常。

Purpose : To study the relationship of the telomere length and telomerase activity to immortalization or malignant t ransformation of the immortalized esophageal epithelial cell line and malignantly t ransformed cell line induced by E6 and E7 genes of HPV 18 type.

目的:探讨端粒长度、端粒酶活性以及端粒酶亚单位组分的表达与食管上皮细胞永生化和恶性转化之间的关系。

Methods 56 patients in esophageal and gastric variceal bleeding were allocated randomly into the control group and the treatment group. All patients were given basic treatment, the CG patients received pituitrin (0.2U/min) though micro infusion pump,octreotide 0.1mg were injected in the TG patients and infused continuously at a rate of 25 礸/h. The efficient hemostasis, rebleeding, the average bleeding time and blood volume were recorded. Adverse reactions such as the queasiness, abdominal distension, abdominal pain, diarrhoea, palpitaition and hypertension were observed.

将经胃镜证实的食管胃底静脉曲张破裂出血患者56例随机分成对照组(n=28)和治疗组(n=28),两组在给予基础治疗的同时,对照组使用垂体后叶素0.2U/min微泵持续静脉滴注;治疗组使用奥曲肽,首次0.1mg静注,再以25μg/h微泵持续静脉滴注止血治疗,比较两组在止血有效率、再出血率、平均止血时间、平均输血量等止血效果及恶心、腹胀、腹痛、腹泻、心悸、胸闷、血压升高等不良反应上的差异,并进行统计学分析。

Results : The telomere length in the SHEE and SHEEC was significantly shorter than that in the normal esophageal epithelial tissue , but maintained a stable length.

结果:SHEE 细胞和SHEEC 细胞的端粒平均长度比正常食管上皮细胞的明显缩短,但稳定维持在一定长度范围内。

Results The major cause was peptic ulcer, the secondary was chronic gastritis in all cases, the next one was esophageal varix for non-old patients and tumour for old patients.

结果 消化性溃疡为上消化道出血的主要病因,其次为慢性胃十二指肠炎和食管炎以及恶性肿瘤、食管胃底静脉曲张及Mallory-Weiss综合征。

Results The tissue of 3 cases of ACC in the esophagus was mainly composed of square shape gland epithelial cell and variant myoepithelial cell, mesh shape cavity crack and the tubular, the entity shape arrangement, the cavity crack content basophilia and acidophilia the secretion. There was transmigration of superficial epidermis in 1 case of ACC; All 3 cases were positive of CK, H-CK, P63, S-100 (endochylema /nucleus), EMA, and Bcl-2. Case 3 was positive of CerbB-2 and P53. Case 2 was CD117, AAT, SMA, PAS/AB.

结果 3例食管腺样囊性癌的癌组织主要由立方形腺上皮细胞和变异的肌上皮细胞组成,呈筛孔状腔隙、管状、实体状排列,腔隙内含嗜碱性和嗜伊红分泌物;3例食管腺样囊性癌中例1表面上皮有移行;免疫组化:3例CK、H-CK、P63、S-100、EMA、Bcl-2均,例3 CerBb-2,P53,例2 CD117,AAT、SMA,PAS/AB。

Barrett's esophagus, the most important risk factor in the deelopment of adenocarcinoma of the esophagus, is a metaplastic condition in which the normal squamous epithelium of the esophagus is replaced by columnar or glandular epithelium.

Barrett食管,是食管的正常的鳞状上皮被柱状或腺状上皮所取代的一种化生状态,为食管腺癌的发生中的最重要的危险因素。

The binding of pisum sativum lectin to its receptors on normal human esophageal epithelia and changes of its distribution during neoplastic transformation were investigated by immunohistochemistry technique.

应用免疫组化技术研究了豌豆凝集素与其受体在人食管上皮的结合,以及在癌变过程中的分布变化。

METHODS: The expression of Elk-1 in fresh esophageal cancer tissues and their corresponding normal mucosae was detected immunohistochemically by means of tissue microarray. Its correlation with clinical characteristics was evaluated and analyzed by univariate analysis. All statistical analyses were performed by SPSS version 13.0. RESULTS: Expression level of transcription factor Elk-1 increased in 78.5%(84/107) ESCC tissues compared with their matched normal esophageal epithelium.

方法应用高通量的组织芯片以及免疫组化技术,分析了107例食管鳞癌患者的Elk-1的表达情况,在其蛋白质水平上,研究Elk-1在食管鳞癌组织和配对的正常粘膜组织的差异表达量,探讨该转录因子在食管鳞癌中的表达与临床病理各变量之间的关系。

Group one consisted of 300 patients whose esophageal stumps were treated by a purse stitch using a clamp. Group two included 180 patients whose esophageal stumps were oversewn by 6-8 interrupted stitches, or by a continuous stitch along the stump before the anvil was in place.

第一组300例,食管残端用荷包钳法作荷包处理;第二组180例,食管残端在荷包钳处理的基础上,再间断全层缝合食管壁并结扎缝线,或沿食管残端连续全层缝合一周,放入抵钉座后结扎缝线。

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