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颗粒细胞

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Spinous layer: the innermost prickle cells are polygon, and from the inside to outside, they become more and more flat, they are connected to granular cells with some space between, besides the spinous process, under normal condition, there is cell tissue fluid that could help the metabolism of cells in between.

棘层:棘细胞自里向外由多角形渐趋扁平,与颗粒细胞相连,各细胞间有一定空隙,除棘突外,在正常情况下,还含有细胞组织液,辅助细胞的新陈代谢。

The expression of Bcl-2mRNA and P53mRNA in hippocampus after 16Hz, 130dB infrasound treatment In 1 day group, Bcl-2mRNA and P53mRNA were expressed lightly in CA1-CA3 areas in hippocampus and dentate gyrus. Blood vessels dilated lightly. In 7d group, Bcl-2mRNA and P53mRNA were more expressed in areas mentioned above. Dilation of capillaries and small vessels was more obvious. Bcl-2mRNA and P53mRNA were strong positive in endothelial cells of vessels. In 14d group, Bcl-2mRNA and P53mRNA expression was obviously increased in pyramidal cells of hippocampus and granular cells of dentate gyrus, showing deep blue staining. a The endothelial cells in some vessels were also strong positive for Bcl-2mRNA and P53mRNA. Dilation of capillaries and small vessels was lessened. In 21d group, Bcl-2mRNA and P53mRNA expression was decreased in pyramidal cells. In 28d group, little change about the expression and distribution of Bcl-2mRNA and P53mRNA was observed. Lots of Bcl-2mRNA and P53mRNA were scattered in cortex of temporal lobe around hippocampus and callosal gyrus area. Dilation of capillaries and small vessels was lessened obviously. The expression of Bcl-2mRNA and P53mRNA in hippocampus after 16Hz, 90dB infrasound treatment.

次声作用后Bcl-2mRNA和P53mRNA在海马的表达,16Hz、130dB次声作用1d组:两者在海马〓区和齿状回轻度表达,海马内血管轻度扩张;7d组:两者表达在上述区域较1d增多,微血管和小血管扩张较显,血管内皮细胞内可见呈强阳性表达的Bcl-2mRNA和P53mRNA;14d组:海马锥体细胞和齿状回颗粒细胞内Bcl-2mRNA和P53mRNA阳性表达明显增多,呈深兰色,在部分血管内皮细胞内两者强阳性表达,微小血管扩张状态较7d减轻;21d组:锥体细胞胞浆内Bcl-2mRNA和P53mRNA表达减弱;28d组:上述表达及分布与21d组相比无明显改变,海马周围颞叶皮层和扣带回区域亦可见大量散在分布的Bcl-2mRNA和P53mRNA表达,血管扩张状态已明显减轻。90dB次声作用1d-7d后,较对照组无明显变化,14d-21d后轻度表达,28d后,Bcl-2mRNA和P53mRNA表达较强。

Pathology findings:there were 294 cases of clear renal cell carcinoma (83.76%),including 2 cases of cystis renal cell carcinoma ,27 cases of Grannular renal cell carcinoma ( 7.69 %), 14 cases of papilliform renal cell carcinoma , 6 cases of the mixed type renal cell carcinoma,10 cases of other cell types .

病理结果:透明细胞癌294 例(83.76%,其中囊性肾细胞癌2例),颗粒细胞癌27 例(7.69%),乳头状肾细胞癌14例(3.98%),肾混合细胞癌6例(1.7%),其它癌10例。

Pathology findings:there were 294 cases of clear renal cell carcinoma (83.76%),including 2 cases of cystis renal cell carcinoma ,27 cases of Grannular renal cell carcinoma ( 7.69 %), 14 cases of papilliform renal cell carcinoma , 6 cases of the mixed type renal cell carcinoma,10 cases of other cell types . Followup was achieved in 263 cases (74.93%),with tie 3、5year and 10 year survival rates being 70.45 %(124/ 176),53.3%(40/75) and 23.8%(5/21) respectively.

病理结果:透明细胞癌294 例(83.76%,其中囊性肾细胞癌2例),颗粒细胞癌27 例(7.69%),乳头状肾细胞癌14例(3.98%),肾混合细胞癌6例(1.7%),其它癌10例。263 例(74.93 %)获得随访,随访时间6个月~12 年,3 年、5 年和10年生存率分别为70。

Pathology findings:there were, 294 cases of clear renal cell carcinoma (83.76 %), including 2 cases of cystis renal cell carcinoma , 27 cases of Granntdar renal cell carcinoma ( 7.69 %), 14 cases of papilliform renal cell carcinoma , 6 cases of the mixed type renal cell carcinoma, 10 cases of other cell types .

病理结果:透明细胞癌294例(83.76%,其中囊性肾细胞癌2例),颗粒细胞癌27例(7.69%),乳头状肾细胞癌14例(3.98%),肾混合细胞癌6例(1.7%),其它癌10例。263例(74.93%)获得随访,随访时间6个月~12年,3年、5年和10年生存率分别为70.45%(124/176)、53.3%(40/75)和23.8%(5/21)。

Results] There were 11 cases with clear cell carcinoma; 1 case, granular cell carcinoma; 4 cases, mixed cell carcinoma; 1 case, multilocular cell carcinoma; 1 case, papillary renal carcinoma; 2 cases, chromophobe cell carcinoma and 1 case, collecting duct carcinoma.

结果] 11例透明细胞癌,1例颗粒细胞癌,4例混合细胞癌,1例多房囊性肾细胞癌,1例乳头状癌,2例嫌色细胞癌,1例集合管癌。

Results IL-6R immunoreactive cells were observed in the anterior of optical area,the ventromedial nucleus,the periventricular nucleus and arcurate nucleus of the hypothalamus.The strongly stained cells are concentrated in the granule cell layer of the dentdate gyrus and the pyramidal cells of the CA1-CA2 fields of the hippocampus.IL-6R positive cells are also detected in the cortex, the ventromedial nucleus of the thalamus,bed nu stria,olfaltory tubercle.

结果 IL-6R 免疫反应性细胞主要分布在下丘脑的视前区、腹内侧核、室旁核和弓状核;在海马, IL-6R 阳性细胞呈强阳性,密集分布于齿状回颗粒细胞层和 CA1~ CA2锥体细胞层;在大脑皮层、嗅结节、丘脑腹内侧核、终纹床核等处也有 IL-6R 阳性细胞。

Following anovulatory dose of hCG, the positive reactivity of Cyclin G1 in preovulatory granulosa cells was decreased. Furthermore, the luteinized granulosa cells showed the weak staining.

至排卵前卵泡颗粒细胞,Cyclin G1表达水平减弱,当颗粒细胞分化为黄体细胞后表达水平进一步减弱。

Methods Human luteinized granulosa cells were isolated from follicular fluid obtained during oocyte retrieval of IVF-ET program and were cultured with M199 media plus various concentration of follicle stimulating hormone (FSH, 0% 0.5% 5% 10% 25% 50) or human chorionic gonadotropin(hCG, 0% 5% 10% 50% 75% 100IU/ml). The media were collected and PAPP-A in the media were measured by time-resolved fluoroimmunoassay.

将来自体外受精—胚胎移植的卵泡黄素化颗粒细胞分离纯化后,利用不同剂量促卵泡激素(FSH,0、0.5、5、10、25、50)或人绒毛膜促性腺激素(hCG,0、5、10、50、75、100IU/ml)刺激体外培养的颗粒细胞,收集培养液,采用时间荧光免疫分析法测定培养液中PAPP-A的量。

The results were:① The number of pCREB immunoreactive neuclei and total amount of pCREB in the subnuclei of rat amygdala, Dentate gyrus and Cornu Ammonis 3(CA3) were increased after FS.

在DG颗粒细胞层内,对照组的pCREB阳性细胞核数目很少,成线状散在分布;而FS后pCREB阳性细胞核的数目明显增多,成带状密布于整个DG颗粒细胞层。

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