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GnRH could markedly suppress progesterone secretion of cultured GCs with or without FSH and LH co-treatments. E〓 could invert the suppression of GnRH completely, also had the additive action on secreting progesterone with GnRH co-treatment. Mel partially released the suppression action of GnRH.

GnRH能强烈地抑制体外培养的颗粒细胞分泌孕酮,其抑制作用几乎不受FSH和LH影响;Mel仅表现部分地缓解了GnRH的抑制效应,但没有逆转。E〓不仅可以完全逆转GnRH的抑制作用,进而与GnRH叠加促进颗粒细胞分泌孕酮。

GnRH could mar Red I y suppress progesterone secretion of cultured GCs with or without FSH and LH co-treatments. E2 could invert the suppression of GnRH completely, also had the additive action on secreting progesterone with GnRH co-treatment. Mel partial ly released the suppression action of GnRH.

GnRH能强烈地抑制体外培养的颗粒细胞分泌孕酮,其抑制作用几乎不受FSH和LH影响;Mel仅表现部分地缓解了GnRH的抑制效应,但没有逆转。E_2不仅可以完全逆转GnRH的抑制作用,进而与GnRH叠加促进颗粒细胞分泌孕酮。

The effects of FSH and IGF-Ⅰ on apoptosis and production of steroids in granulose cells cultured in vitro.

体外培养颗粒细胞过程中,FSH和IGF-Ⅰ在促进类固醇激素生产,抑制颗粒细胞凋亡中的作用。

The expression of INH-B in granulose cells can reflect the functional state of the cells.

颗粒细胞INH-B表达可反映细胞自身的功能状态,颗粒细胞功能减退是卵巢反应减低、发育卵泡数目减少的主要原因之一。

With the method of flow cytometry, hemocyte cells were classified into hyalinocyte and granulocyte by forward and side light-scatter parameters analysis according to cell size and granule.

流式细胞仪根据血细胞的大小和颗粒,经正、侧光散射参量分析,也将血细胞分为透明细胞和颗粒细胞

The integrinα_6β_1-LN interaction is probably a local regulator of the ovary. LN may play an important role in granulosa cell luteinization during the periovulatory phase through interfering the function of LN/hCG receptors and enhancing the progesterone production of GCs.

LN通过与细胞表面粘附分子整合素α_6β_1(integrinα_6β_1)相互作用,可能为卵巢内的一种局部调节因素,干扰LH/hCG受体功能并增强颗粒细胞孕酮的产生,在围排卵期颗粒细胞黄素化过程中发挥重要效应。

Results There were spontaneous apoptosis in the cultured granulosa cells and ceramide could signi-ficantly increase apoptosis (P<0.05).En hanced apoptotic surf was observed by flow cytometry.

结果 体外培养的颗粒细胞存在自发性凋亡,神经酰胺处理的颗粒细胞凋亡率明显高于对照组(P<0.05);流式细胞术分析可见增强的凋亡峰。

The large granulocytes show characteristics of holocrine, and the small hyalinocytes are a transient type of residual cell bodies of large granulocytes after the holocrine process finished.

颗粒细胞还具有全质分泌的特性,小透明细胞极可能是大颗粒细胞全质分泌后的一时性残余胞体。

In the assay of isolated granule cell culture, we found that Slit2 still repels neuronal migration.

通过对单独的颗粒细胞培养的观察,我们发现在没有Bergmann胶质细胞时Slit2同样也可以排斥颗粒细胞迁移。

The cerebellum consists of five distinct concentric layers: white matter, internal granule layer, Purkinje cell layer, molecular layer, and external granule layer in young rodents.

在年幼的啮齿类动物中,小脑包含5种不同的集中分布层:白质、内颗粒细胞层、浦肯野氏细胞层、分子层和外颗粒细胞层。

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