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Doxy treatment inhibits the activity of MMPs, the SMC proliferation ofintimal, neointimal hyperplasia and vascular remodeling which suggesting Doxy treatmentbe useful in preventing restenosis after PTCA.

用球囊扩张法可成功建立大鼠颈总动脉损伤膜型;Doxy 可以显著降低血管损伤后 MMPs 活性,抑制内膜 SMCs 的增殖、新生内膜增生以及后期的管腔重构,提示它可能具有防治 PTCA 术后再狭窄的作用。

In most severe cases, the external carotid artery, strap muscles of the neck, Vagus nerve, Hypoglossal nerve and the lingual branch of the Trigeminal nerve are also removed.

在最严重的情况下,颈外动脉,肩带肌肉的颈部,迷走神经项,舌下神经号和舌分行的三叉神经也删除。

Cervical spondylosis is due to cervical back muscle strain as well as the unbalanced paravertebral muscle strength caused by long-term working with head drop, which thereby leads to a set of syndrome: cervical intervertebral disc degeneration, narrow intervertebral space, unstable vertebrae unit, protruded or extruded nucleus pulpous; hyperosteogeny, ligament pachynsis, narrow neural canal or nerve root canal; oppressed nerve root and spinal cord, stimulated vertebral artery and sympathetic nerve; aching and discomfort cervix; numbness and disability of the body; functional disorder in relieving the bowels; dizziness and nausea, etc.

颈椎病的原理及颈椎功能锻炼的原理 Theory of Cervical Spondylosis and Cervical Vertebrae Dirigation 颈椎病是由于长期低头工作等原因所导致的项背肌劳损、颈椎周围肌群肌力不平衡,从而使颈椎间盘退变、椎间隙狭窄、椎节失稳、髓核脱出或突出、骨质增生、韧带肥厚,使椎管或神经根管狭窄,压迫脊髓、神经根、刺激椎动脉及交感神经,出现颈部酸痛不适、躯体麻木无力、大小便功能障碍、头晕恶心等症状的一组综合症。

We sutureed the fascia and muscle in front of the vertebral tansverse process and got the result of aneurysm outpocketing. Another case was an injury of the internal jugular vein (0.3cm near the skull fundus) with shock, we pressed the distal internal jugular vein with a conglomeration of gelatin songe.

其一为椎动脉在第二颈椎左侧横突处的损伤并伴假性动脉瘤,缝合横突前方残余颈长肌及筋膜,达到与动脉瘤外包裹术相同的效果;另1例为颈内静脉出颅处的不全离断伴休克,远心端在不能结扎和缝合止血的情况下,用明胶海棉揉成团块填塞、压迫,止血疗效肯定。

Objective The arteria carotis externa was ligated, and arteria carotis interna was kept opening The left carotid artery was exposed and placed over an ultrasonic flow probe. The brain flow volume was recorded with an ultrasonic volume meter. The pursiness time of mice was observed to evaluate the effect of Erigeron breviscapus pellets on cerebral ischemia.

目的 应用二道血流速度流量仪超声探头测定大鼠颈总动脉以反映云南植物药业有限公司提供的灯盏花颗粒对脑血流量的影响;记录小鼠断头后张口喘气时间,观察灯盏花颗粒的抗脑缺血作用。

The left carotid artery was expose and placed over an ultrasonic flow probe.The brain flow volume was recorded with an ultra-sonic volume meter.The pursiness time of mice was observed to evaluate the effect of tianma xingnao capsule on cere-bral ischemia and anoxia.Methods The permeability of normal blood-cerebral barrier was investigated in mice.

目的 应用二道血流速度流量仪超声探头测定大鼠颈总动脉,以反映云南省昭通制药有限公司提供的天麻醒脑胶囊对脑血流量的影响;方法记录小鼠断头后张口喘气时间,观察天麻醒脑胶囊的抗脑缺血缺氧作用;小鼠尾静脉注射Evans溶液,测定脑组织Evans的吸光度以反映药物的血脑通透性。

Results rcbf in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rcbf明显下降,以术后24小时最明显,至4个月时仍明显低于正常,呈慢性持续性下降的趋势;各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍,至4个月时记忆功能障碍持续存在。

Results rCBF in prefrontal cortex, parietal cortex, hippocampus and subcortex obviously decreased, especially on 24 h post operation, and was lower than that of normal group on 4 mon post operation obviously. rCBF showed a tendency to decline. The cognitive functions of rats were obviously reduced after 1 mon of the chronic cerebral hypoperfusion and lasted until 4 mon.

结果 大鼠双侧颈总动脉永久结扎后额叶、顶叶、海马及皮质下区的rCBF明显下降,以术后24小时最明显,至4个月时仍明显低于正常,呈慢性持续性下降的趋势;各实验组大鼠从术后1个月开始即出现明显的记忆功能障碍,至4个月时记忆功能障碍持续存在。

Hypoxic-ischemic encephalopathy experimental grouping: Sixteen successful C57/BL6J mice models, aged 7 days, were randomized into 2 groups: experimental group (n =8), following ligation of right common carotid artery, mice were placed in the closed container containing 0.08 volume fraction of oxygen and 0.92 volume fraction of Nitrogen gas, and taken out 1.5 hours later; 3 μL ESCs were injected into the right cerebral ventricle at about 1 week, and control group (n =8), in which, the same amount of PBS was injected into the right cerebral ventricle.③ At 12 weeks after transplantation, the survival and migration of induced ESCs labeled by Lac-Z in the spinal cord and brain were observed by zymologic method.

缺氧缺血性脑病实验分组:将造模成功的鼠龄7 d的C57/BL6J16只小鼠随机分为2组:实验组8只,结扎右侧颈总动脉后将小鼠置入含体积分数0.08氧气和体积分数0.92氮气的密闭容器内,1.5 h后取出;1周后在右侧脑室内注入3 μL诱导胚胎干细胞。

Methods MID was established by inverse injection of thrombus into external carotid artery to observe the pathologic changes in hippoeampus and cortex region of brain and the ability of spatial learning and memory with Morris Water Maze.

颈外动脉逆行插管注入血栓建立MID大鼠模型,观察大鼠大脑皮质及海马的病理形态变化,同时应用Morris水迷宫检测MID大鼠的空间学习记忆的变化。

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