颈动脉

During the year following treatment, diaries recording falls and other symptoms suggested a strong association between "nonaccidental" falls and cardioinhibitory carotid sinus syndrome.

在治疗后的一年中，经过对病人昏厥和其它症状的的连续性记录发现，在昏厥和心脏抑制性颈动脉窦综合症之间存在著明显的相关性。

During the year following treatment, diaries recording falls and other symptoms suggested a strong association between "nonaccidental" falls and cardioinhibitory carotid sinus syndrome.

在治疗后的一年中，经过对病人昏厥和其他症状的的连续性记录发现，在昏厥和心脏抑制性颈动脉窦综合症之间存在著明显的相关性。

METHODS: Thirty-six rabbits underwent perivascular injury at both carotid arteries, followed by a 1.5% cholesterol diet. After 90 days, rabbits were randomly divided into 6 groups and treated 5 times with vehicle or ETC-216 at 5, 10, 20, 40, or 150 mg/kg dose every 4 days.

36只兔子在双侧颈动脉制造外周血管损伤，随机给予1.5%的胆固醇餐。90天后，兔随机分为6组，用赋形剂或ETC-216以5，10，20，40，150 mg/kg 剂量每4天给药1次。

CASE DESCRIPTION: We present a patient with bilateral carotid FMD presenting with a large petrous pseudoaneurysm.

病例介绍∶我们介绍了一例双侧颈动脉FMD合并一个大的颞骨岩部假动脉瘤患者。

BACKGROUND: Pseudoaneurysms of the petrous carotid artery may occur in the setting of trauma, dissection, invasive tumors, or as a complication of surgery.

背景∶颈动脉颞骨岩部的假动脉瘤可能由于创伤、解剖操作、浸润性肿瘤而出现，或者作为手术的并发症出现。

Among the various endovascular techniques that have been tested so far, we propose self-expandable covered stents as ideal for treating arterial aneurysms and pseudoaneurysms of the petrous and cavernous carotid segments.

迄今为止各种已经检验过的血管内操作方法中，我们建议植入自我可膨胀扩张盖，这是颈动脉颞骨岩部和壁内段动脉瘤和假动脉瘤的理想治疗方法。

Objective: The purposes of the present study are as follows: 1 To study the effect of direct contact with VSMC on transdifferentiation of MSC; 2 To construct MSC of Dual-stable expression of AT2R gene medicated by tetracycline regulatable system.; 3 To investigate the effects of AT2R gene medicated by tetracycline regulatable system on neointimal hyperplasia in rat carotid arteries after balloon angioplasty.

本实验体外观察MSC与VSMC在直接接触培养下的分化情况，并以MSC为载体，通过体外细胞基因转染及筛选，获得双重稳定受到强力霉素调控表达AT2R基因的MSC，将此受到调控表达的AT2R基因导入大鼠颈动脉球囊损伤动物模型中，观察MSC细胞移植实现AT2R基因在体可调控表达在新生内膜中形成的作用及潜在意义。

①Rat MSC and VSMC were cultured and identified, respectively. MSC were labeled with DAPI firstly, and then co-cultivated with VSMC. The changes of morphology and ultrastructure of co-cultured cells were observed. Immunfluorescence analysis was performed by using monoclonal antibodies against specific antigen.②We established the regulatable system in two steps: a stable MSC line expressing rtTA has been constructed and characterized firstly by transfected with pUHD 17-1hyg and then selected by hygromycin B; in a second step, this line was used for trandfer the AT2R gene to MSC to get the well establishing double stable MSC lines;③The expression of AT2R regulated by doxycycline was evaluated by western blot;④The MSCs were transduced into rat carotid arteries with regulatable AT2R gene after the establishment of rat carotid balloon injury restenosis model. The intimal/medial area ratio were measured by digital analysis system.

研究方法：(1)密度梯度离心法及胶原酶消化法分别培养原代大鼠MSC及VSMC，细胞共培养并行免疫荧光化学染色和透射电镜观察超微结构；(2)组成受Dox调控的哺乳动物表达系统的四种成分的转化、扩增及提纯并酶切鉴定；(3)采用常规分子生物学方法连续两个回合转染体外培养的MSC，并分别采用发光计检测不同细胞克隆萤光素酶活性改变以及RT-PCR方法检测AT2R目的基因mRNA表达情况，根据各个细胞克隆受Dox调控表达的程度，选择低背景、高诱导表达AT2R的细胞系，作为双重稳定MSC细胞系；蛋白免疫印迹法观察该细胞系在Dox调控下AT2R表达的时相性、持续性及在不同浓度Dox调控下的表达情况；(4)建立大鼠颈动脉球囊损伤动物模型，将双重稳定MSC在术中导入血管，分别于14 d、28 d进行病理切片，检测可调控AT2R对新生内膜增生的影响；采用RT-PCR免疫组织化学免疫荧光等技术观察AT2R基因在新生内膜中的表达以及细胞外基质成分表达的改变，TUNEL法检测血管组织中细胞凋亡的变化情况。

To summarize clinical experience of using stent in carotid artery stegnosis patiant by cerebral protection device.

目的 总结在使用脑保护装置下进行颈动脉狭窄支架成形术的临床经验。

Methods: Eight cases (6 males,2 females, stegnosis from 50% to 94%, mean 68.7%,four cases 0%) with carotid artery stenosis were investigated.

研究8例颈动脉狭窄患者(男性6例，女性2例)，狭窄率50%～94%，平均68.7%，其中4例狭窄率0%，拟在使用脑保护装置下行CAS手术。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷