靶

The electrons in the pre-plasma are accelerated by the ponderomotive force of propagating laser pulse, and the dependences of the maximum electron energy on the laser intensity and the pre-plasma density are examined.

当激光脉冲与靶直接作用时，靶中的电子由于J×B机制而得到加速，所获得的能量比预等离子体中电子低。

It is shown that adiabatic shearing fracture is main reason of resulting in the plugging occurrence. The residual adiabatic shear bands in the destroying process, which distribute reticulately from the surface of penetrated hole to internal area, is very wide. It is easy to result in falling of fragments....

冲塞的发生以绝热剪切破坏为主，靶板中残留的剪切带比较宽大，由弹孔表面向靶板内延伸，呈网状分布，易造成碎块的脱落，另外，绝热剪切带的形成与塑性力学静载下滑移线的形成密切相关，其走向与滑移线的方向基本一致

These results indicated that hASB-8 may mediate the interaction between target proteins and ubiquitination complex, and correlate with the tran- scription process of target genes in tumor cells.

这些试验提示hASB-8蛋白可能介导肿瘤细胞中靶蛋白和泛素复合体之间的相互作用，并与肿瘤细胞靶蛋白转录调节有关

It can also be used to monitor the downhole steeling tool and control the trajectory to approach the target and hit it.

可实时监控井下导向工具，控制井眼轨迹按设计的轨迹逼近靶区并中靶。

Month sheep (weight:2030 kg) were treated with localized papain instillations to generate heterogeneous emphysema, subsequently underwent BLVR using one?way flap device at subsegment.

通过CT确定靶区后，在X线造影定位并确定靶支气管后，经纤维支气管镜通过导丝和放送装置在肺气肿亚段放入1~2个单向活瓣支架，术后给予3 d抗炎治疗。

These results indiacated that tranferring macrophages combinedwith cytokines could be a new adoptive immunotherapy protocol foradvanced cancer,and rTNF used in vivo locally could induce andactivate macrophages to kill tumor cells.Monocytes when activatedunderwent a series of phenotypic and functional changes includingthe expression of IL-2R which may provide an important immunoregu-latory pathway.The presence of lectin-like molecules on thesurface of monocytes and tumor cells may bring theeffector/target cells together,thus facilitating the inductionof apoptosis in target cells by triggering the production ofcytolytic factors and the modification of target of targer cell surface anti-gens.(such as HLA-DR).

综合以上结果可以得出以下结论：转输巨噬细胞并结合细胞因子的联合应用是肿瘤继承性免疫中的又一新的、有潜力的方法；抗肿瘤细胞因子rTNF可通过激活巨噬细胞在体内抑制对其不敏感的肿瘤细胞的生长；人单核细胞在一定条件下激活后，可表达IL-2R，进而一方面增强其自身对IL-2的敏感性，另一方面在体内也具有调节T细胞功能的作用；单核细胞和肿瘤细胞上存在的凝集素类受体可促使两种细胞之间在凝集素介导下相互接近，并诱发单核细胞产生细胞毒因子，以及通过调节靶细胞上表面抗原的表达，促进诱导靶细胞的细胞凋亡。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

The ballistic experiments of tungsten long-rods penetrating composite laminates and steel target are investigated. The experimental results show that the penetration performance of torqued long-rod is stronger than that of non-torqued rod.

本文首先进行了钨合金杆弹侵彻有限厚度的钢靶和复合靶的侵彻实验，实验结果表明预扭转钨合金杆弹侵彻贯穿能力比未扭转钨合金杆弹要高。

Therefore,a sequence specific artificial zinc finger proteinis created when replacing the amino acids in the specific sites of C2H2 zinc finger protein and then fusing the protein to other activation or repression domains,while remaining the backbone of the zinc finger protein unchange...

ZFP可以介导靶基因的转录调控，抑制或激活特定基因的表达与配体依赖的靶基因激活或抑制；对DNA进行修饰，如人造限制性内切酶，重组酶，整合酶；抗病毒感染等。因此，人造锌指蛋白应用前景广阔，研究价值显著，是未来人类基因治疗的革命性的工具。

Two sticks and an apple,say the bells at whitechapel.

提到枪靶和靶心，就数大钟圣马格丽特。

They go to town. Would you just ask them?

他们在城里你能问他们吗？

Ossein pretreated for a2 weeks period exhibited the maximum% yield incase of bone gelatin, while the yield from intact skin was higher than that realized incase of de-scaled skin.

预处理时间达2星期的骨胶原表现出最高的骨明胶百分产量，然而从未处理鱼皮中得到的产率比去鳞的鱼皮得到的要高。