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In order to evaluate the roles played by telomerase activity and apoptosis gene in malignant transformation of mammary atypical ductal hyperplasia, as well as the ultrastructure characteristic and regular pattern in the transformation, we investigated the expression of telom- erase genes and apoptosis related genes (p53 and bcl-2) and ultrastructure characteristic in precancerous lesion-mammary atypical ductal hy- perplasia, and compared with breast carcinoma and benign hyperplasia.

本文研究端粒酶基因、凋亡相关基因(p53、bcl-2)在乳腺癌前病变-乳腺导管非典型增生中的表达情况,探讨乳腺导管非典型增生上皮的超微结构特征,并与乳腺癌、乳腺导管单纯性增生进行对比,旨在研究端粒酶活性变化及凋亡相关基因在乳腺导管非典型增生上皮细胞癌变过程中的作用及意义,并研究乳腺导管非典型增生上皮细胞恶性转化过程中的形态结构特点及变化规律。

The Heterotrophic bacteria, nitrosomonas, epiphyte and rhizosphere in non-rhizosphere zones are more than the contrast in the sample with the inoculants and enzyme, contrary to the nitrobacter and denitrifying bacteria.

菌剂和酶制剂的加入使得非根际泥样异养细菌、真菌、放线菌和亚硝酸细菌比对照组稍高,硝酸细菌和反硝化细菌则较少;而根际泥样中加菌剂和酶制剂组微生物数量比空白组高出1—2个数量级,在投加菌和酶制剂后酶活性无论在根际还是非根际都得到提高,高于对照组约5—6个酶活单位。

However, because of the nonspecificity of the NOS inhibitors and the compensatory interactions among NOS isoforms, the ultimate roles of endogenous NO derived from the entire NOS system are still poorly understood.

然而,由于一氧化氮合酶抑制剂的非特异性以及一氧化氮合酶亚型(神经元型一氧化氮合酶,诱生型一氧化氮合酶,内皮型一氧化氮合酶)之间的相互代偿作用,研究人员对于体内由一氧化氮合酶系统合成的内源性一氧化氮的根本作用还不是很清楚。

The degradation of DDTs fitted pseudo-first-order kinetics equation. The constants of degradation rate of DDTs between sterilized control and unsterilized control as well as between sterilized laccase addition and unsterilized laccase addition were close respectively, with the latter much higher than the former.

DDTs的降解过程符合拟表观一级动力学方程,非灭菌对照处理和灭菌对照处理之间,以及非灭菌加酶处理和灭菌加酶处理之间DDTs的降解速率常数分别相近,且加酶处理的降解速率常数明显高于对照处理。

The Correlation between enzyme activities and physical properties of spruce forests soil The acid phosphatase was conducive to the increase of natural capacity, capillary capacity, saturated water capacity, non-capillary capacity, total porosity, non-capillary porosity, and the decrease of bulk density; the catalase and proteinase were conducive to the increase of capillary porosity and water porosity, respectively, these results suggested that catalyze function of soil enzyme directly acted the formation of soil physical structures.

土壤酶活性与土壤物理性质的相关性酸性磷酸酶活性的增强,有助于土壤自然含水量、毛管水含量、饱和水含量、非毛管水含量、总孔隙、非毛管孔隙的增加及容重的减小;过氧化氢酶和蛋白酶活性的增强分别有助于毛管孔隙和水占孔隙的增加。

The differences of zymograms were significant between three blackfly species and each species had its own special zymogram. The main band among intraspecific individuals or between the larvae and pupae was alike, however, other enzyme bands were different.

结果 3蚋种的EST同工酶酶谱共显示10条酶带,种间存在明显差异,具有各自的特征性酶谱,种内个体之间、幼虫与蛹之间酶谱主带相同,非主带略有差异。

The one carbon unit transfer reaction involving in the tetrahydrofolate coenzymes has caused great interest which is very important in the living system and has played an important role in the designing and syntheses compounds (especially the anti-cancer and LCD materials). In our study it was found that benzimidazolium salt has the ability to transfer one or two one-carbon unit and is a kind of new tetrahydrofolate coenzymes model. This research provides new method for biomimetic synthesis.

在非酶催化条件下,不仅实现了与生物体内相类似的一碳单元转移反应,而且可以转移具有不同官能团的取代&一碳单元&,使这种一碳单元转移反应传递的功能化一碳单元更加多样化,这方面强劲的研究工作进展,将为异常活跃的合成化学提供更多常规合成方法难以实现或实现不理想的仿生合成新方法。

The soil microorganisms quantities, microbial diversity index, microbial biomass carbon and the cellulose decomposition strength significantly reduced with increasing of heavy metal concentration, but the soil basal respiration rate were positively enhanced. The soil urease, alkaline phosphatase and polyphenol oxidase in the lead zinc mining area were sensitive. The invertase and catalase were not obvious inhibited to the heavy metals.

该矿区土壤微生物区系组成和微生物活性显著不同于临近非矿区土壤,随着重金属含量的增加,土壤微生物数量、微生物多样性指数、微生物生物量碳以及纤维素分解强度均显著降低,但土壤基础呼吸却明显升高;土壤脲酶、碱性磷酸酶、多酚氧化酶对铅锌矿较为敏感,而蔗糖酶和过氧化氢酶受到的抑制作用不明显。

Results of non-reducing sodium dodecyl sulphate polyacrylamide gel electrophoresis of the supernatant and aggregate precipitate formed in refolding process show that except being refolded to native egg white lysozymes, the reduced-denatured lysozymes can also form the aggregates with molecular weights being separately about 30.0 and 35.0 kD, while the reducing SDS-PAGE and the refolding results in the presence of sodium dodecyl sulphate show that these aggregates are formed chiefly through the misconnection of disulfide bonds between the reduced-denatured lysozymes, and the aggregate precipitates are formed through the non-covalent interactions between the aggregates with molecular weight being about 30.0 kD.

复性过程形成的上清和集聚体沉淀的非还原电泳结果表明,除了能复性成天然态的溶菌酶分子外,还原变性蛋白溶菌酶同时还能形成分子量分别约为30.0KD和35.0KD的蛋白溶菌酶分子集聚体;而它们的还原电泳和在SDS存在时的复性结果表明,这些集聚体主要是通过还原变性蛋白溶菌酶分子间的二硫键错配而形成,而集聚体沉淀则是通过分子量约为30.0KD的集聚体分子之间的非共价相互作用而形成。

The nuclear protein encoded by N gene is consist of 422 AA residues (47kDa), Each virion contains 1258 copies that can effectively protect viral RNA from being digested by nucleotidase. The N protein presents a group specificity, it exists in various types and subtypes of VS and plays a very important role in transcript copy. Due to its characteristics of high antigenicity, the N protein can stimulate the body producing nonneutralized antibody.

它可有效的保护病毒RNA免受各种核酸酶的消化。N基因编码的N蛋白呈群特异性,为许多型和亚型所共有,有高的抗原性,刺激机体产生非中和抗体,且在转录复制中担任了重要的角色。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。