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In patients with biopsy-proven cardiac amyloidosis, late gadolinium enhancement frequently occurs in a peculiar pattern. On the basis of the gold standard, EMB, noninvasive CMRI can be used to diagnose or rule out cardiac amyloidosis with good sensitivity and excellent specificity in a clinical routine setting.

在心肌活检证实为淀粉样变性的患者中,钆延迟增强扫描常常会以特异的方式出现,在此金标准基础上,EMB和非侵入性CMRI可用于诊断或排除心肌淀粉样变性,仅有较高的敏感性和优越的特异性。

The above results suggests that the hydrolase and FMO in microsomes are involved in the formation of M1 and M2 respectively.

黄素单氧化酶的特异性抑制剂甲巯咪唑可以显著地抑制M2的形成,但对M1的形成无明显的抑制作用,且M1在肝微粒体中的形成为NADPH非依赖性,上述结果提示参与M1和M2代谢的酶分别为肝微粒体中的水解酶和黄素单氧化酶。

Moreover, it was shown that the dispersion ability of SWNT in aqueous solution had a significant improvement after coating with NOMA.

检测器件在每个修饰阶段的电学性能的变化证明了NOMA对SWNT的非共价糖基化修饰及用CNTFET来检测糖-凝集素特异性识别作用的可能性。

Firstly, the SSH was used to isolate tissues or organs specific expression genes in different development stages of plant. These genes provide evidence for explaining the molecular mechanism of plant development. Then SSH was widely used to isolate genes related to resistance under biological or abiological stress in different plants and the molecular mechanism of the resistance was primarily elucidated.

首先, 官中的组织特异性表达的基因,为揭示植物生长发育过程的分子机理提供了有效手段;另外,在不同植物中,该技术被大量应用于分离各种生物及非生物胁迫条件下诱导表达的抗性相关基因,可以揭示植物抗逆的分子 SSH 技术已开始应用于分离与次生代谢产物合成相关的基因。

The morphology of polyembryonic rice IR36-Shuang could be differentiated into 2 types: uncomplete twin seedlings and complete twin seedlings. There were 2 types in uncomplete twin seedlings, i.

IR36-双在双胚苗性状的表现形态上有其特异性,在同一纯合株系的群体内双胚苗的苗位有非完全双苗和完全双苗两种类型。

Previous studies have found the major metabolic way of clivorine in male rat liver microsomes was to form pyrrolic metabolites. The above results suggested that there is sexual difference of metabolism in rats. The major in vitro metabolic way of clivorine in guinea pig was hydrolysis.

FMO的特异性抑制剂methimazo1e可以显著地抑制〓的形成,但对〓的形成无明显的抑制作用,且〓在肝微粒体中的形成为NADPH非依赖性,上述结果提示参与〓和〓代谢的酶分别为肝微粒体中的水解酶和黄素单氧化。

In order to verify the Fluorescent-Quantitation PCR kit specific for Borna disease virus nucleoprotein, compare molecular beacon with common probe and study its practical application, the sensitivity, distinctness, repeatability and stability were tested on BDV and non-BDV infected cells, as well as non-infected controls. Human and animal samples were also tested by the kit. The lowest quantity of virus RNA detected by the kit was 2.5×101, which corresponded to 1 virus copy.

为评价博尔纳病病毒(Borna disease virus, BDV)核蛋白荧光定量PCR试剂盒的各项指标,比较分子信标探针相对普通探针的优势,并了解其实际检测效果,本课题组使用BDV OL持续感染细胞株、非BDV病毒序列转染的OL细胞、正常的OL细胞,对BDV RT-PCR试剂盒的敏感性、特异性、重复性和稳定性进行评估,同时检测部分临床病人和动物外周血液RNA。

Magnetic Bead is widely used in biomedical engineering for its high surface area, coupling capacity and convenience of non-touch manipulation.

磁珠技术具备固相化试剂的特点以及免疫反应的特异性,因其比表面积及偶联容量大、非接触式操控简单方便等优势,近年来在生物医学工程中得到了广泛的应用。

To prepare the phosphorylated PRAS40 (Ser183) antibody, We chosen 10-amino acid including Ser183 as antigen peptide through antigenicity and hydrophobicity analysis, hinged on keyhole limpet hemocyanin, and used the KLH-peptide to immunize rabbits. After antibody serum titer detection by enzyme linked immunosorbent assay, the antibody was purified with rProtein A sepharose fast flow and dephosphorylated antigen membrane. The antibody titrate reached 1:10 000 after purification and its special property was enhanced with absorption treatment of dephosphorylated antigen membrane. In addition, we used rabbit anti-PRAS40 antibody and the phosphorylated PRAS40 (Ser183) antibody to detect PRAS40 expression in several cell lines, including the normal cells HL7702, HEK293, tumor cells HepG2, A549 and S180. There were no quite difference among these cells; otherwise, we observed the decreased phosphorylation level of Ser183 after amino acid withdrawal treatment.

为了制备PRAS40(Ser183)磷酸化多克隆抗体,本实验通过蛋白疏水性抗原性分析设计多肽抗原,用其免疫家兔获得抗血清, ELISA检测其效价为1:10 000; Western blotting法检测发现,通过rProtein A Sepharose亲和层析纯化并经非磷酸化的抗原条吸附处理后的抗体可以明显提高磷酸化抗体的特异性;用PRAS40抗体及PRAS40(Ser183)磷酸化抗体对正常细胞HL7702、HEK293及肿瘤细胞HepG2、A549、S180的检测显示:磷酸化的Ser183在不同细胞中表达差异不显著,而在经细胞饥饿处理的HEK293细胞中却明显观察到了S183磷酸化水平随氨基酸含量降低而减弱的现象。

The nuclear protein encoded by N gene is consist of 422 AA residues (47kDa), Each virion contains 1258 copies that can effectively protect viral RNA from being digested by nucleotidase. The N protein presents a group specificity, it exists in various types and subtypes of VS and plays a very important role in transcript copy. Due to its characteristics of high antigenicity, the N protein can stimulate the body producing nonneutralized antibody.

它可有效的保护病毒RNA免受各种核酸酶的消化。N基因编码的N蛋白呈群特异性,为许多型和亚型所共有,有高的抗原性,刺激机体产生非中和抗体,且在转录复制中担任了重要的角色。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。