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PART ONE INVESTIGATION OF THE MOLECULAR MECHANISM OF THE IMMUNO-MODULATION EFFECT OF HALR USING AFFYMETRIX CHIP Objective: Augmenter of liver regeneration is a nonspecific factor that can stimulate hepatocytes proliferation.

第一部分运用基因芯片技术研究hALR的免疫调控作用的分子机制目的:肝再生增强因子(Augmenter of liver regeneration, ALR)是一种非特异性、具有热稳定性、不同于以往已知的促肝细胞增殖的肝细胞再生因子。

Superoxide dismutases family are thought to be one of the first lines of antioxidant defense and are highly efficient in protecting cells and tissues against oxidative stress by catalyzing the dismutation of superoxide radicals to form hydrogen peroxide and molecular oxygen.

但由于活性氧分子反应的非特异性,它们也会破坏宿主机体细胞内的功能蛋白分子、不饱和脂肪酸分子和核酸等,对细胞造成严重的伤害,进而导致机体生理机能的损伤和免疫系统的破坏。

Methods The anti-tumor activity of Phellinus linteus was estimated by the longevity of EAC mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the IL-2 concentration in serum of tumorous mice was determined by ELISA.

目的 观察桑黄对肿瘤的抑制作用及对机体免疫功能的影响方法以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用,以炭末廓清实验观察荷瘤小鼠非特异性免疫功能,以ELISA法测定荷瘤小鼠血清IL-2浓度。

By Faradic impedance technique,a significant increase of the interracial electronic transfer resist- ance R_ was determined when the SH-ssDNA probe/Au electrode hybridized with its comple- mentary sequence.

实验中对DNA探针的自组装时间、杂交温度、杂交时间和阻抗测量液等实验条件进行了观察和优化;通过选择自组装液中SH-ssDNA探针和RSH的浓度,减少DNA在金电极表面的非特异性吸附,同时保证金电极表面自组装的SH-ssDNA探针有合适的疏密度,提高了杂交效率。

Methods Rat models of cerebral edema after cardiac arrest were established by water-airproof bottle obturation methods, and CPR was carried out at once.

脑水肿是指脑组织的含液量增多而引起的脑容量增加,它是中枢神经系统受到各种外源性或内源性有害因素刺激时所产生的一种最常见的非特异性反应。

There are some problems in developing microcosmic syndrome differentiation, such as lack of standard for syndrome differentiation, contradiction between single microcosmic index and the entirety, nonspecificity of the relationship between microcosmic indexes and syndromes, and the influence of disease on microcosmic syndrome differentiation, discrepancy between the essence study of TCM syndromes and the clinical practice.

微观辨证&有其优越性和局限性,&微观辨证&的发展尚存在一些问题,诸如:中医证候尚未规范化、微观指标单一性与整体性的矛盾、微观指标与证候对应的非特异性、疾病对&微观辨证&产生的影响、&证本质研究与临床治疗脱节等。

However, because of the nonspecificity of the NOS inhibitors and the compensatory interactions among NOS isoforms, the ultimate roles of endogenous NO derived from the entire NOS system are still poorly understood.

然而,由于一氧化氮合酶抑制剂的非特异性以及一氧化氮合酶亚型(神经元型一氧化氮合酶,诱生型一氧化氮合酶,内皮型一氧化氮合酶)之间的相互代偿作用,研究人员对于体内由一氧化氮合酶系统合成的内源性一氧化氮的根本作用还不是很清楚。

Results:It is suggested that the drug significantly protectes liver from CCl4,thioacetamide and galactosamine in mice and rats,lowers the activity of enzyme ALT in serum,shorten the sleep duration of CCl4-damaged mice induced by embuter,inhibites HBsAg in vitro,and potentiates non-specific immunity in mice and rats.

结果:研究表明,该药对四氯化碳、硫代乙酰胺和氨基半乳糖引起小鼠及大鼠的急性肝损伤有明显的保护作用,能降低谷丙转氨酶;缩短CCl4肝损伤小鼠戊巴比妥钠的睡眠时间;抑制体外乙肝病毒表面抗原;对非特异性免疫有一定增强作用。

Pepsinogens are zymogens of pepsins,aspecific proteases working as digestive enzymes in vertebrate stomach,of which biological and molecular properties have been extensively studied.

胃蛋白酶原是胃蛋白酶的前体,是脊椎动物中普遍存在的非特异性蛋白消化酶,胃蛋白酶的生物学特性及分子特性已得到了充分研究。

Litopenaeus vannamei were continuously fed by basic diets containing three levels (1%, 0.5%, 0.1%) Ig-Guard respectively for 20 days, and the basic diets as blank control. Phenoloxidase, acid phosphatase, alkaline phosphatase, lysozyme activity of the serum and superoxide dismutase, catalase activity of the muscle, and protein concentration of the serum and the muscle were detected in the 5, 10, 15, 20 day.

采用连续投喂的方法,饲喂凡纳滨对虾 20 d,分别测定了第5,10,15,20 d血淋巴的酚氧化酶、溶菌酶、酸性磷酸酶、碱性磷酸酶及肌肉匀浆液的超氧化物歧化酶、过氧化氢酶等非特异性免疫因子活性,并对血清及肌肉匀浆液中蛋白进行定量。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。