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Methods Fifteen dogs were randomly divided into 3 groups. Group A acted as the control group without CPB; group B and group C were subjected to cardiopulmonary bypass and crossclamping the aorta for 90 min. MP or saline was injected intravenously before surgery. Plasma levels of IL-1β、TNF-α、IL-6、IL-8 and IL-10 were measured at the following time points: before MP or saline were administered, aortic declamping, 30 min and 90 min, after aortic declamping. Immediately after the animals was killed, pulmonary arterial rings were obtained and mounted in organ chamber for assessment of endothelial function with endothelium-dependent or non-endothelium-dependent studies.

健康家犬15只,随机分为3组,A组:不进行CPB,作为非体外对照组;B组:麻醉后注射生理盐水10mL,常规全麻和CPB,主动脉阻断90min;C组:麻醉后静脉给予甲泼尼龙5mg/kg,其余处理同B组。B、C组分别在手术前及主动脉开放前、开放后30min和90min 4个时间点采动脉血,放免法测定血浆白介素-1β(IL-1β)、肿瘤坏死因子-α、白介素-6(IL-6)、白介素-8(IL-8)和白介素-10(IL-10)水平;手术结束时,A、B、C 3组均取右肺动脉段,固定于张力传感器,测定血管环内皮依赖性和非内皮依赖性扩张能力的变化。

It was found that the addition of negative charge inducing agent increased the electrostatic level obviously, the addition of a small amount of positive charge inducing agent decreased visibly the electrostatic level, and the addition of inactive liquid charge inducing agent reduced the electrostatic level significantly in the fluidized bed.

实验结果显示负静电剂的加入,使得整床的静电水平显著升高;正静电引发剂的少量加入,流化床内的静电水平有明显降低;非活泼液体静电引发剂的注入,流化床内的静电水平显著下降。

Methods The rat models of heart failure were established by left anterior descending coronary artery deligation. After 6 w, 24 surviving rats were divided into sham,model and Ramipril groups at random,8 rats in each,and were treated with medicines by intragastric administration respectively. At 10 w, left ventricular enddiastolic pressure, left ventricular systolic pressure,+dp/dtmax anddp/ dtmaxof left ventricular pressure were measured.

结扎大鼠左冠状动脉前降支并饲养6 w的16只存活大鼠,随机分为模型组及雷米普利组,每组8只,另取8只大鼠为假手术组,连续灌胃给药4 w后测定大鼠血流动力学参数,ELISA方法检测血清及左心室非梗死区AngⅡ的含量,RTPCR 法测定左心室非梗死区心肌组织AT1R mRNA表达水平,Masson染色观察非梗死区心肌胶原的沉积。

The levels of blood lipid, blood sugar and hematuria acid were compared in the fatty and nonfatty groups according to BWI. The levels of blood lipid, blood sugar and hematuria acid were also compared in the two groups according to sex and BWI.

对4640例体检者检查资料进行整理分析,按性别、年龄分组,比较体重指数与血脂、血糖和血尿酸的水平;按BMI分为肥胖组和非肥胖组,比较两组之间血脂、血糖和血尿酸的水平;进一步按性别和BMI比较两组之间血脂、血糖和血尿酸的水平。

Methods: After the sorting and analysis of data in the physical examination of 4640 cases, the comparisons between the BMI and blood lipid, the levels of blood sugar and hematuria acid were compared in the groups according to sex and age. The levels of blood lipid, blood sugar and hematuria acid were compared in the fatty and nonfatty groups according to BWI. The levels of blood lipid, blood sugar and hematuria acid were also compared in the two groups according to sex and BWI.

对4640例体检者检查资料进行整理分析,按性别、年龄分组,比较体重指数与血脂、血糖和血尿酸的水平;按BMI分为肥胖组和非肥胖组,比较两组之间血脂、血糖和血尿酸的水平;进一步按性别和BMI比较两组之间血脂、血糖和血尿酸的水平。

There were five groups in the examination of cellular levelK562 group,K562/A02 group,K562+ADM group,K562/A02+ADM group and K562/A02+TTD+ADM group).The non-cytotoxicity doses to cell lines K562 and K562/A02 of TTD were got by MTT assay.Using flow cytometry (FCM assay to examine the intracellular ADM concentration.There were three groups in the examination of genic,zymologic and protein levelsK562 group,K562/A02 group and K562/A02+TTD group).The mRNA expression of MDR was measured by fluorescent quantitative reverse transcriptase polymerase chain reaction(RT-PCR.The expression levels of glutathione-S-transferase and topoisomerase Ⅱ were determined by immunohistochemical technique.

细胞水平检测实验分5组(K562组、K562/A02组、K562+ADM组、K562/A02+ADM组和K562/A02+TTD+ADM组),采用MTT法检测TTD对K562和K562/A02细胞的非细胞毒性剂量,流式细胞术检测细胞内阿霉素的浓度,基因、酶学、蛋白水平检测实验分3组(K562组、K562/A02组和K562/A02+TTD组),采用RT-PCR法检测mdr1 mRNA的表达,免疫细胞化学方法检测谷胱甘肽S转移酶π和拓扑异构酶Ⅱ的表达水平,Western-blotting法检测P-糖蛋白和bcl-2表达。

First, the angular velocity function and maneuver load for certain maneuver flight (including hover, dive-hike and these two combined) are set up. The simulation results of the vibration of double-disk rotor system with cantilever supported on rigid bearings show that rotor would be apparently deformed under maneuver load. Second, the performance of oil force of SFD in maneuver flight is analyzed. The results show that in maneuver flight, the SFD with centering spring will become eccentric and its oil force will be time-related and offset-related.

首先,建立了水平盘旋、俯冲拉起及盘旋+俯冲拉起复合机动三种机动飞行条件下的机动角速度函数,并确定了对应机动飞行条件下的机动附加载荷(附加离心力和附加陀螺力矩),分析了带刚支的双盘悬臂转子系统在机动飞行条件下的振动特性,发现发动机转子在机动飞行时会发生明显变形;随后,分析了非定心挤压油膜阻尼器的油膜力特性,机动飞行时,油膜轴颈在机动附加载荷的作用下偏离外环中心,使得带定心弹支的挤压油膜阻尼器也变成了非定心挤压油膜阻尼器,其非定心挤压油膜力是瞬态时变的,并且与SFD油膜轴颈偏移量和进动形态有关;然后,在经典的Jeffcott转子系统中引入带定心弹支的挤压油膜阻尼器,分析了机动飞行时非线性转子系统的振动特性,发现挤压油膜阻尼器油膜力的非协调特性也反映到转子系统的振动响应中;之后,对机动飞行条件下带挤压油膜阻尼器的双盘悬臂转子系统的振动特性进行了分析,并重点分析、总结了俯冲拉起机动飞行时,系统结构参数和工作状态参数(转速比、机动飞行半径、机动角速度等)对该系统振动特性的影响。

First, the angular velocity function and maneuver load for certain maneuver flight (including hover, dive-hike and these two combined) are set up. The simulation results of the vibration of double-disk rotor system with cantilever supported on rigid bearings show that rotor would be apparently deformed under maneuver load. Second, the performance of oil force of SFD in maneuver flight is analyzed. The results show that in maneuver flight, the SFD with centering spring will become eccentric and its oil force will be time-related and offset-related. Then, SFDs are introduced into typical Jeffcott rotor system. The whole system will be statically displaced in maneuver flight and the nonsynchronous components of oil force appear in the response of rotor system.

首先,建立了水平盘旋、俯冲拉起及盘旋+俯冲拉起复合机动三种机动飞行条件下的机动角速度函数,并确定了对应机动飞行条件下的机动附加载荷(附加离心力和附加陀螺力矩),分析了带刚支的双盘悬臂转子系统在机动飞行条件下的振动特性,发现发动机转子在机动飞行时会发生明显变形;随后,分析了非定心挤压油膜阻尼器的油膜力特性,机动飞行时,油膜轴颈在机动附加载荷的作用下偏离外环中心,使得带定心弹支的挤压油膜阻尼器也变成了非定心挤压油膜阻尼器,其非定心挤压油膜力是瞬态时变的,并且与SFD油膜轴颈偏移量和进动形态有关;然后,在经典的Jeffcott转子系统中引入带定心弹支的挤压油膜阻尼器,分析了机动飞行时非线性转子系统的振动特性,发现挤压油膜阻尼器油膜力的非协调特性也反映到转子系统的振动响应中;之后,对机动飞行条件下带挤压油膜阻尼器的双盘悬臂转子系统的振动特性进行了分析,并重点分析、总结了俯冲拉起机动飞行时,系统结构参数和工作状态参数(转速比、机动飞行半径、机动角速度等)对该系统振动特性的影响。

Randomly adopted 1000 students from 6 country middle schools and 4 country elementary schools, and get 813 available subjects. We can find that: the percentage of Left-behind children is the largest in the whole children, especially Left-behind children who have only one parent; and mentally healthy situations of Left-behind children are poorer than those who are not, the poorest are children who are looked after by compeers or even no rearings; the situations of children who have been Left-behind children also are not so good, there are significant differences mentally healthy between them and those who have not been, while anxiety scores are only a little lower. And there are differences in sex, grade, quarter, single or not and years parents being out among those who are Left-behind children. There are differences of parenting styles among different styles of children caring. Totally speaking, the scores on positive parenting styles of no left-behind children(such as warmth of father and mother) are higher than those who are and who have been left-behind children, but the scores are obviously lower on negative parenting styles such as punishment from father or intervening punishment from mother. The regression equation of anxiety scores on left-behind children set by parenting styles also depends on children caring styles. Positive parenting behaviors of parents and caring people have positive influences on mentally healthy of children, for instance, some supporting and mood warmth., while some negative behaviors such as rejection have negative influences.

随机抽取了江西省的6所农村中学和4所农村小学,调查学生被试共计1000人,有效被试为813人,对调查数据进行分析后发现:留守儿童所占的比重在全体儿童中最大,尤其是单亲看护人的留守儿童;而且,留守儿童的心理健康状况也显著低于非留守儿童,情况最差的是同辈看护或无看护的留守儿童;曾留守儿童的心理状况也不尽如人意,它与非留守儿童的心理健康差异达到了显著水平,心理焦虑总分只是稍低于留守儿童总体;并且,留守儿童的心理健康同样存在着性别、年级、独生与否、住宿与否以及父母打工年数的差异;不同看护类型的留守儿童父母教养方式存在着差异,总的来说,非留守儿童积极性的教养方式(如父亲温暖、母亲温暖等)得分要高于留守儿童和曾留守的儿童,而在很多消极性的教养方式如父亲惩罚、干涉,母亲干涉惩罚等等上,留守儿童与曾留守儿童的得分又要显著高于非留守儿童;家庭教养方式对留守儿童焦虑总分的回归方程视儿童的看护类型而定,父母和看护人的一些积极性的抚养行为对儿童的心理健康有着积极的影响,比如情感温暖或者支持温暖等,但是一些消极的比如拒绝等对留守儿童的心理健康就有负面的影响。

In addition, a model computing the nonadiabatic coupling terms in photochemistry of pericyclic reactions has been suggested at the level of HuckelHubbard theory, and a series of nonadiabatic transitions for such reactions have been discussed based on the model proposed.

此外,还在H-H理论水平上建立起光化学周环反应的态-态非绝热偶合计算模型,用这种理论模型讨论了一系列光化学周环反应中的非绝热跃迁问题,获得了势能面、非绝热偶合项和立体选择性。

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