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Objective To analyze humoral immune response to nucleic acid vaccines (VR1012/TPA/HG-MSP1-17 for intracellular expression or VR1012/HG-MSP1-17 for secretion) which contain Plasmodium falciparum Merozoite surface protein 1(MSP1) 17 block gene and gene fragment of several T cell epitopes from MSA1, MSA2, RESA, IL-1 and TT and to monitor the effect of DNA-immune sera on parasite inhibition.

摘 要:目的检测以恶性疟原虫裂殖子表面蛋白1的17区片段基因为基础的复合核酸疫苗(分泌性的VR1012/TPA/HG-MSP1-17和非分泌性的VR1012/HG-MSP1-17)诱导小鼠的体液免疫反应和免疫血清对疟原虫生长的抑制能力。

The paper consists of following contents:(1)starting with a historicalreview of the use-of-force,this paper reveals a paradoxical evolvementof the two trends in use-of-force,compares the absolutization andinfinity with controllability and finity of the use-of-force,and clarifiesnew characteristics of the use-of-force in post-Cold War era;(2)bysystematically analyzing the era background from the viewpoints ofeconomic globalization,political multipole,military high tech,national separatism and the hegemonism,the paper clarifies factorslimiting and stimulating the use-of-force;(3)by analyzing the lawbackground mainly from the viewpoint of international laws,the paperespecially centralizes the discussion on restrictions made by moderninternational laws on the use-of-force and their limits,dissects thechallenges brought up by the high tech war to international laws;(4)the use-of-force by UN and other regional international organization;(5)refuting the theory of"humanitarian intervention"advocated bythe USA and certain western countries,the paper expatiates the rightrelations between human rights and sovereignty,and demonstrates therightness of the sovereignties and UN;(6)the basic guidelines of theuse-of-force in the post-Cold War era.

分别从经济全球化、政治多极化、军事高技术化以及民族分离主义的泛滥、霸权主义的恶性膨胀等方面系统分析冷战后武力使用的时代背景,揭示出冷战后时代同时存在的限制、约束武力使用的因素,以及诱发、刺激武力使用的因素。(3)主要从国际法的角度分析武力使用的法律背景,着重探讨现代国际法对武力使用的规范和制约作用以及这种作用的有限性,同时剖析现代高技术战争对国际法提出的挑战。(4)主要探讨联合国以及区域性国际组织在冷战后使用武力的实践以及存在的问题。(5)驳斥以美国为首的某些西方国家所鼓吹的&人道主义干涉&论,阐述人权与主权的正确关系,论证主权国家和联合国并没有过时,不能用非人道手段解决人道主义问题。(6)系统提出了冷战后国家间使用武力应遵守的基本准则。

The majority of primary testicular lymphoma is diffuse large B cell lymphoma and the prognosis is poorer than other testicular malignancy. Treatment with anthracycline-based chemotherapy and radiotherapy after orchiectomy is recommended.

原发性睾丸非霍奇金淋巴瘤的主要病理类型是弥漫性大B细胞淋巴瘤,其预后较其他部位恶性淋巴瘤差,手术切除后行以蒽环类为基础的化疗联合放疗是其主要的治疗手段。

Then the author analyzes empirically China's terms of trade from 1981,and the causes of the change in the net barter terms of trade by means of regression analysis ,which can be quantitied.we get the results that China's net barter terms of trade had a declining trend while its income terms and factorial terms of trade had been improved,and the net barter terms of trade positively correlates with actual tariff rate,exchange rate and negatively correlates with GDP,besides,the factors which can not be quantitied such as pure price fighting,inappropiate tariff sytem,foreign-invested enterprises's tranfer pricing and region trade agreement also lead to the above trend of China's net barter terms of trade,and the change in China's net barter terms of trade had a neglect impact on international trade benefit.

得出中国价格贸易条件总体上存在下降趋势,收入、要素条件呈现改善的趋势;实际关税率、汇率与价格贸易条件存在正相关关系,GDP指数与其负相关。出口企业恶性价格竞争、不合理的关税体制、外资企业的转移定价、区域贸易集团是造成中国价格贸易条件下降的非量化因素。此外,本文分析了1981-2004年价格贸易条件变动导致的中国国际贸易利益变化,发现价格贸易条件变动对中国国际贸易利益产生了一定的负面影响。最后,本文在分析中国价格贸易条件变动环境的基础上,认为中国工业化阶段不高、贸易限制性政策实施空间的减小、&合成谬误&现象及知识经济时代的到来会在一定时期内对价格贸易条件变动不利。

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