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Herein, we report the enantioselective total syntheses of slagenins A-C and their antipodes. Starting from readily available ethyl -4-chloro-3-hydroxy-butanonate, elongation of the carbon chain with diazomethane, followed by oxidation of the given α-diazoketone using distilled DMD, afforded a key intermediate α-ketoaldehyde .

本文从方便易得的-4-氯-3-羟基-丁酸乙酯出发,经重氮甲烷延伸碳连、DMD氧化相应的α-重氮酮,制得α-酮醛;该化合物与尿素在氢氟酸作用下,以协同方式非对映选择性的直接构建了cis-四氢呋喃并[2,3-d]咪唑啉-2-酮双环结构,进而合成了天然产物slagenins A、B、和C的对映体。

Electropolar solvent such as THF may destroy the polyetherimide layer,while non-electropolar solvent such as petroleum ether cannot solve vinyl acetic acid cobalt.

极性溶剂如四氢呋喃会溶解PEI层,而非极性溶剂如石油醚又不能溶解丁烯酸钴。

The shape and size of trabeculae, which form the internal bridges between the upper and lower surfaces of the elytra, depend on the species of beetles.

不过,和以往的认识不同的是,两种甲虫前翅的小柱具有类似的结构,它们均为非中空的实柱,并由中心部和环状的几丁质纤维层构成。

A long string of popular albums resulted, including Mein Liebeslied (2000), Napoli Adieu (2001), Drei Stimmen d'Amour (2001; co-featuring Mara Kayer and Francine Jordi), Mein Gefьhl (2002), Das Beste von Monika Martin (2002), Himmel aus Glas (2003), Eine Liebe Reicht fьr Zwei (2004), Ave Maria: Lieder zur Stillen Zeit (2004), Ein Kleines Glьck (2005), Schmetterling d'Amour (2005), Heute Fьhl' Ich Mich Wie Zwanzig (2006), and Aloha Blue (2007)- most of which were Top 20, if not Top Ten, hits in Austria and anywhere from Top 50 to Top 100 hits in Germany.

专辑的流行造成一长串,包括炒面Liebeslied(2000年),那不勒斯再见(2001年),科特迪瓦爱德雷伊之声(2001;合作具有马拉戈耶尔和弗朗辛霍尔迪),炒面Gefьhl(2002年),达斯Beste马丁冯莫妮卡(2002年),希默尔澳大利亚玻璃(2003年),Eine利伯Reicht黵Zwei(2004年),圣母颂:之歌楚Stillen宰特(2004),艾因KleinesGlьck(2005年),Schmetterling德爱(2005年),霍伊特Fьhl'非物质文化遗产密歇根魏Zwanzig(2006年),和阿罗哈蓝色(2007)-其中大部分是前20,如果不是前十名,在奥地利安打,任何地方从50强的前100点击在德国。

The theorems of Ibn al-Haytham, Omar Khayyam and Nasir al-Din al-Tusi on quadrilaterals , including the Lambert quadrilateral and Saccheri quadrilateral , were the first theorems on elliptical geometry and hyperbolic geometry , and along with their alternative postulates, such as Playfair's axiom , these works had a considerable influence on the development of non-Euclidean geometry among later European geometers, including Witelo , Levi ben Gerson , Alfonso , John Wallis , and Giovanni Girolamo Saccheri .

定理伊本Haytham,欧玛尔海亚姆和纳西尔基地丁铝土司上quadrilaterals ,包括德兰伯特四边形和萨凯里四边形,是第一个椭圆形的几何定理和双曲几何,并连同其替代假设,如普莱费尔的公理,这些作品有相当发展的影响非欧几里德几何之间稍后欧洲geometers ,包括Witelo ,列维本格森,阿方索,约翰瓦利斯和乔瓦吉罗拉莫萨凯里。

Objective To investigate the inhibitive effect of sodium phenylbutyrate combined with gefitinib on NB4 cells.

目的 探讨联合应用苯丁酸钠与吉非替尼对NB4细胞的抑制效果。

The author has studied the kinetics of hydrogenation of a,β-unsaturated aldehydes andketones such as cinnamaldehyde and 2-butylene cyclopentanone,β-ionone over amorphousalloy NiB catalyst at atmospheric pressure of H2 as well as effects of reaction conditions onthe kinetics.

作者以肉桂醛和2-亚丁基环戊酮、β-紫罗兰酮为代表重点研究了非晶态NiB催化α,β-不饱和醛酮常压下选择加氢的反应动力学。常压下该反应是准一级反应。

Chiral separation of nine enantiomers, which include lobeline, tropicamide, promethazine,propranolol, atenolol, cyclandelate, salbutamol, fenfluramine and benzhexol, has been for the first time achieved by nonaqueous capillary electrophoresis.

用非水毛细管电泳成功地分离了洛贝林、托吡卡胺、普萘洛尔、阿替洛尔、环扁桃酯、沙丁胺醇、苯海索、芬氟拉明和异丙嗪等9种手性化合物。

The curative effect of Triprolidine Hcl to 60 cases with chronic nettle rash was studied by adopting different approaches,which provides theory basis for clinical applying of Triprolidine Hcl-a new histamine H1 receptor antagonist.

为探讨盐酸曲普利啶治疗慢性荨麻疹的疗效,将60例慢性荨麻疹患者,随机分为两组,盐酸曲普利啶治疗组30例及特非那丁组30例,结果两组间有显著性差异,为新一代组胺H1受体拮抗剂—盐酸曲普利啶的临床应用提供了一定的理论依据。

The Molar conductivity indicates that all the complexes are nonelectrolyte. IR spectra show the ligand is bonded with RE ion through its oxygen atom in hydroxyl group of phenol; NO3 is coordinated as a symmetrical chelating bidentate group; the coordinated atoms of DMF and DMSO are the oxygen atoms in carbonyl and sulfoxyl groups. Fluorescence spectrum suggests that the Tb3+complexes have characteristic luminescence and its fluorescence intensity is enhanced after doping with La3+, Gd3+, Y3+, influence of doping ions and neutral ligands have also been discussed.

摩尔电导率表明,所有配合物均为非电解质;红外光谱及核磁共振氢谱表明,对叔丁基杯[8]芳烃通过酚羟基的氧原子与稀土离子配位;硝酸根为双齿螯合配位;DMF和DMSO则分别通过羰基氧和亚砜基氧与稀土离子配位;配合物的荧光光谱表明,所有Tb的配合物具有较强的特征荧光,掺杂La~(3+)、Gd~(3+)、Y~(3+)离子对Tb~(3+)的荧光有较强的增强作用。

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Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

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