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Viral vector mainly contain adenovirus, retrovirus,adeno-associated virus and so on, but it has potential danger of safety; it isrepeled by immune system when it is injected to organism for a greatimmunogenicity. An injection with adenovirus vector with highconcentration, it leads to serious inflammatory reaction of liver. Viralvector such as liposome and polycation are commonly used lately. But,liposome and polycation have low specificness and targetness of genetransfer tissue, have lower transfection efficiency and short period ofgene expression, for they can be phagocytized by endothelial system.

许多的载体,病毒载体和病毒载体以前已广泛应用,病毒载体主要包括腺病毒,逆转录病毒,腺相关病毒等;但病毒载体在安全性方面存在潜在的危险;免疫原性比较强,注射到机体后很快会被机体的免疫系统排斥,当静脉注射高浓度的腺病毒载体会使肝脏发生严重的炎症反应;病毒载体目前常用的有脂质体及多聚阳离子聚合物;但脂质体和阳离子聚合物介导基因转移缺乏组织的特异性和靶向性,转染效率较低且易被网状内皮系统吞噬,基因表达时间短;因此研制新型的病毒载体已成为研究的热点,纳米颗粒具有小尺寸效应,表面效应,随着颗粒直径变小,比表面积将会显著增大,故具有很高的化学活性,因而纳米成为了最有应用前景的病毒载体。

The feasibility of a spheric polishing by FRP-1 flexible polishing machine is proved by experiments.

为了研究FRP-1型球面柔性抛光机加工球面零件的可行性,利用FRP-1型球面柔性抛光机对球面光学零件进行抛光实验。

Viewing from the angle of the science of law and taking "rights" as the text for analysis,this article discusses the theoretical divergence on "the rights of nature" between the anthropocentrists and non-anthropocentrism.The anthropocentrists criticize the rights of nature from four aspects,its humanity,impracticality, uncontrollability and non-equivalence of its duties.The n...

从法学视角切入,以&权利&作为分析文本,论述了人类中心主义与人类中心主义在&自然权利&上的理论分歧,人类中心主义者从权利的属人性、权利义务的不对等性、主张自然权利的现实性以及自然权利的不可操作性四个方面对自然的权利提出了批判,而人类中心主义者指出权利概念的在不断地扩展,人类中心主义不可能完全解决好人与自然的关系,自然权利存在着转化为在法律上具有可操作性的可能,并且自然权利理论已在法律实践领域拓展,对自然的权利进行了辩护,由此提出了&人类中心主义&、&自然的权利&的环境伦理定位。

Based upon the results of experiment and calculation of several representative unsymmetric composite laminates , the coupling characteristics of unsymmetric laminate was studied.

为了解决机翼的扭转发散、载荷重新分布及操纵反效和操纵效率等问题,基于对称复合材料的各向异性及相对于普通复合材料更好的可设计性,以几种典型对称复合材料层板的试验及计算为基础研究了对称层合板的各种耦合特性,并进行了对称复合材料机翼的设计,得到了满意的结果。

The application results from fluorination showed microwave heating could accelerate chemical reactions markedly. The reaction time could be shortened 50% at least than that of conventional heating. The relationship between fluorinating agents\' structure and their activity was studied systematically. In addition, an anhydrous KF with higher activity was prepared by using expansion effect of microwave heating. As we known, solvents were very important to reaction. The comprehensive study showed some less polar aromatic solvents could be used as dipolar solvents. In addition, they had better effect than dipolar solvents in some occasions, such as fluorination of chlorobenzaldehydes and chlorinated diphenyl ketones etc. The primary applications of ionic liquids were also studied which indicated reactions with ionic liquids as solvents were more efficient and simple.

研究表明,微波是一种节能高效的加热方式,在微波作用下的卤素交换氟化反应具有反应速度快、转化率高、选择性好的优点,其反应时间可较常规加热缩短50%以上;同时也系统地研究了氟化剂种类及制备方式对其反应活性的影响,并利用微波加热的膨化作用制备出了一种活性较高的KF,其活性与喷雾干燥KF相差不大;溶剂对反应具有重要的作用,在此系统地研究了强极性质子溶剂和中等极性质子溶剂的应用情况,发现一些中等极性的质子溶剂如硝基芳烃和氯代芳烃类溶剂在氯代苯甲醛类化合物的氟化反应中具有比强极性质子溶剂更好的使用效果。

The method rescinds the relationship between peer identifier and logical location in topology construction, so that the network has the good tolerance capability for the non-transitivity connectivity nodes.

更多包含传递连通节点的网络拓扑的问题,提出了确定性DHT的拓扑构造方法,从拓扑构造上解除了传递连通节点的标识与逻辑位置对应的关系,使网络对传递连通节点具有较好的容忍能力。

for the past few years, with the increases of non-war military actions such asinternational peace keep, maintaining stability and handling contingencies, doing rescue and relief work, public health emergency,closing and controlling the border, protection of ocean rights and interests and maintenance of security of maritime strategy passage,and foreign-related military action etc.every country in the world is trying to construct theoretical system on medical support of non-war military action.concerning characteristics of medical support of non-war military action, this paper discuss measures and methods from actual conditions in sanatoriums, so as to prepared for assigned task of medical support.

近年来,随着国际维和、维稳处突、抢险救灾、突发公共卫生事件、边境封控、维护海洋权益和海上战略通道安全、涉外军事行动等战争军事行动的增多,世界各国正着力构建战争军事卫勤保障的理论体系。本文围绕军队战争军事行动卫勤保障特点,结合疗养院实际,探讨疗养院做好战争军事行动卫勤保障的措施办法,有备应对可能赋予的卫勤保障任务。

The State subdivides non-prescription drugs into Class A drugs and Class B drugs according to the level of safety.

国家根据处方药品的安全性,将处方药分为甲类处方药和乙类处方药。

Some asymmetric vortex solutions are obtained, which yield the side forces and yawing moments having the order of magnitude agreeing with experimental data.

本文获得了大迎角旋转体在不同对称边界条件下的对称涡解,其中一些对称涡解的侧向力和偏能力符合实验数据的量级。

It is found that the structure of the ternary electroless Ni-W-P coating is greatly influenced by W content in the deposit. It is also found that the requisite content of phosphorus for amorphous Ni-W-P structure is less than that of Ni-P binary alloy coating, and the more tungsten exists, the less phosphorus is required. The hardness of the deposits will be enhanced as the deposit structures are changed from amorphous to mix-or nanocrystalline structures. The corrosion resistance of Ni-W-P ternary alloy is improved as W content increased, and the passivation of amorphous deposits is formed more easily than that of mix-structure and nanocrystalline deposits.

研究发现,化学镀Ni-W-P三元合金镀层的结构受镀层中钨含量的影响较大,晶态Ni-W-P三元合金镀层所需磷含量较晶态Ni-P二元镀层所需磷含量要低,并且钨含量越高,所需磷含量越少;镀层硬度随镀层结构从晶态→混晶态→纳米晶态转变而增加;镀层的耐蚀性随镀层中钨含量增加而变好,且晶态镀层较混晶态和纳米晶态镀层更易形成钝化区。

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Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时,他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了

The enrich the peopling of Deng Xiaoping of century great person thought, it is the main component in system of theory of Deng Xiaoping economy, it is a when our country economy builds basic task important facet.

世纪伟人邓小平的富民思想,是邓小平经济理论体系中的重要组成部分,是我国经济建设根本任务的一个重要方面。