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静脉注射

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To investigate the hyperglycemic effect on ICAM-1 expression of BBB, we took a dynamic observation of the expression on endothelium of BBB in SD rats with hyperglycemia for 3 days to 6 months, by immunohistochemical method.

为了解超负荷血糖条件下有否血脑屏障内皮细胞ICAM-1的表达,本研究采用SD大鼠尾静脉注射链脲霉素的方法,建立超负荷血糖模型。

On paper, it read like aa relatively minor ordeal of intravenous infusions accompanied by nausea, fatigue and hair loss. No worse, really, than a bad flu with a shocking haircut. Inreality thought, chemotherapy is quite literally pure poison injected directly into the bloodstream.

表面上,化疗只是接受静脉注射,有反胃,疲惫,掉头发等副作用,却不大难捱,最多不过像患上严重流行性感冒,加上一个可怕的发型,但实际上,化疗等於把毒药直接注射到血液中。

METHODS: The rats were treated respectively with single dose of 250 μg.kg-1 LPS intravenously and 50 μg.kg-1LPS interpenetratively per day for 7 days to establish the acute and chronic renal failure models.

分别采用一次性静脉注射250 μg.kg-1和连续7天每天一次腹腔注射50 μg.kg-1 K03肺炎杆菌内毒素,建立大鼠急性及慢性肾功能衰竭模型。

Objective: To observe the effect of azithromycin on intragastric pressure and gastric electrical slow wave, and explore the dependent nerve and receptor.

目的:观察静脉注射阿奇霉素对大鼠胃内压和胃电慢波的影响,并探讨阿奇霉素作用所依赖的神经和受体。

After 24 hours, three injections of 20 mg/kg of methylprednisolone were given intramuscularly at a time interval of 24 hours.

取70只新西兰大白兔经耳缘静脉注射10μg/kg脂多糖,24h后臀肌注射20mg/kg甲基强的松龙琥珀酸钠,共3次,每次间隔24h,制备股骨头坏死模型。

The four most common methods of drug administration are intravenous, oral, intramuscular and intrathecal.

四种最常见的给药方法包括静脉注射、口服、肌肉注射和鞘内注射。

Objective To study the differences of bleomycin-induced pulmonary fibrosis in mice induced by intravenous injection and intratracheal instillation of bleomycin.

目的 探讨静脉注射和气管内滴入博莱霉素对小鼠肺纤维化形成的差异。

Methods Forty C57BL/6 mice (female, 8 wk of age, 17 to 20 g body weight) were randomly divided into two groups (20 mice in each group): in the group V, bleomycin was injected intravenously once in a dose of 150 mg/kg, and in the group I, bleomycin was instilled intratracheally in a dose of 5 mg/kg, respectively.

8周龄雌性C57BL/6小鼠40只,随机分为静脉注射组20只、气管内滴入组20只,分别经尾静脉一次性注射BLM150 mg/kg和气管内滴入BLM5 mg/kg。

BACKGROUND: There is a need for more effective therapeutic methods associated with less side effects for the treatment of inner ear diseases such as idiopathic sudden deafness. Intratympanic steroid injection cause local infiltration and lower systemic side effect, however, the efficacy of treatment was not available.

背景:传统上以类固醇治疗突发性耳聋的投予方式不外乎口服、肌肉或静脉注射,但皆有发生全身性副作用的危险性存在;鼓室内注射类固醇只造成局部的吸收,可降低全身性副作用,但其是否有效则尚待研究。

At the IV dose of 20 and 30 mg/kg, Aloin and Isobarbaloin result appear the mean terminal eliminate half-life(T1/2 β)were 54.1±28.4; 28.7±18.3 and 36.9±21.9;49.7±17.1 min, respectively. The mean area under the serum concentration curve(AUC0-∞)were about 411.655± 13.027;318.213±19.924 and 701.336±116.631;573.278± 86.870μg min/mL, respectively. The mean drug clearancewere 0.165±0.011;0.214±0.016 and 0.149±0.030;0.182±0.035 L/min, respectively.

静脉注射剂量20和30 mg/kg后,其芦荟大黄苷及异芦荟大黄苷分别平均末端排除半衰期(T1/2 β)为54.1±28.4;28.7±18.3和36.9±21.9;49.7±17.1 min,平均稳定状态分布体积为7.668±3.155;6.343±3.522和5.146±2.490;8.525±2.683 L,平均曲线下面积(AUC0-∞)为411.655 ±13.027;318.213±19.924 和701.336±116.631;573.278±86.870 μgmin/mL,平均血浆中药物最高浓度为23.920±5.669;30.442 ±7.537和57.920±27.690;36.373±14.174 μg/mL,平均药物之清除率为0.165±0.011;0.214±0.016和0.149±0.030;0.182±0.035 L/min。

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