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There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体,分别为ET-1、ET-2、ET-3、ET-β,而在人主要是ET-1,在生理条件下,ET-1在血浆中含量较低,约为5ng〓,故ET-1不是一个循环激素,而是局部合成释放,局部起作用的活性物质,半衰期约1小时,ET-1是目前已知的最强的血管收缩剂,对静脉的作用比动脉强,在血管床,ET受体有A、B两型,A型主要分布在平滑肌细胞,B型主要分布在内皮细胞,它可以通过旁分泌途径刺激内膜增生,具有有丝分裂原效应,可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩,使静止期SMC进入增殖期,还可以通过信号传导途径,与bFGF、GTF-β、PDGF等生长因子协同作用,起共有丝分裂原作用。

1St Chakra - base/perinium, red, Earth, survival, grounding, stillness, elephant, earth

第一个脉轮-底部/perinium,红色,尘世,生存,基础,静止,大象、泥土

Rats in the model control group were fed with ethanol and pinguid food by intragastric gavage and were put on the static treadmill of 0 slope, with the frequency of 30 min/d.

模型对照组:给予乙醇+高脂饮食灌胃,放进静止的跑台不运动,0坡度,30 min/d。

In studying the deposition in stastic state and the polarographic analysis of Sn~(2+) in the solution,the production and inhibition of the deposition are also discussed.

通过研究溶液在静止状态下的沉淀情况和 Sn~(2+)的极谱分析,对锡盐电解着色液沉淀的产生和抑制进行探讨。

We propose that ethylene is part of a signaling pathway that modulates cell diision in the quiescent center in the stem cell niche during the postembryonic deelopment of the root system.

我们假设在根系统胚后发育过程中,次乙基调节在干细胞维环境静止中心区域的细胞分裂的一个信号转导通路

Firstly, corona inception voltage of the post insulator and surface leader inception voltage of the bushing versus relative humidity were investigated. The predischarge phenomena in connection with relative humidity were observed under AC voltage by photographing.

首先,对支柱绝缘子的电晕起始电压及套管表面先导起始电压与空气相对湿度的关系进行了研究;用静止照相的方法分别观察了支柱绝缘子和套管在不同相对湿度范围内的工频预放电现象。

Among its many biological activities, the major function of GM-CSF is to stimulate hematogenie stem cells prolification from silent stage to S phage, so that the stem cells can differentiate into granulocyte-macrophage cells.

有4个外显子和3个内含子,基因定位于5号染色体长臂5q21-5q32区,大多数器官均能产生GM-CSF,GM-CSF有多种生物活性,作用于多种细胞谱系,其主要作用是刺激造血祖细胞增殖即从静止期进入S期,并分化为粒细胞---单核巨噬细胞。

Most people resist the retractive or lifting phase ,forcing the body to remain static,and thereby increasing the tension it the muscles.

大多数人总是抗拒内收或延伸的过程,迫使身体保持静止状态,从而增加了肌肉的紧张。

This reflects the fact that Rhodospirillum sp. turns into dormant in the extended stationary phase.

这些都表明静止期后的红螺菌逐渐进入休眠状态。

The variations of the total bacterial counts and CFU in its growth process in the batch culture were monitored.As it grows to stationary phase,Rhodospirillum sp.

分批培养过程中,同时测定红螺菌数和可培养活菌数的变化表明,静止期生长期后的红螺菌难以在固体培养基上形成菌落,进入非可培养状态。

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And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47:5 法老对约瑟说,你父亲和你弟兄们到你这里来了。

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嘿大乌鸦,个别谎言的事不要再-其所有的组织的谎言,在支持。