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青霉素

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The kinetics of PenG hydrolysis catalyzed by penicillin amidase entrapped in the reversed micelles was studied.

研究了青霉素酰化酶在AOT/异辛烷反胶团体系中催化PenG水解反应的动力学。

The thermal inactivation of penicillin amidase entrapped in AOT/isooctane reversed micelles was studied in detail.

研究了青霉素酰化酶在二-(2-乙基己基)琥珀酸双酯磺酸钠/异辛烷反胶团中的稳定特性。

It has been shown that penicillin amidase was very susceptible to the change of temperature, extremely apt to deactivate in the buffer; while the thermostability of enzyme could be improved by an average of 2~4 times in the reversed micelles.

结果表明,青霉素酰化酶对温度非常敏感,在水溶液中极易失活,而经反胶团包埋后,其热稳定性有很大程度的提高,热失活明显减少。

The hydrolysis course of PenG catalyzed by penicillin amidase entrapped in the AOT/isooctane reversed micelles was investigated.

通过将青霉素酰化酶包埋于AOT/异辛烷反胶团中,对PenG酶促水解过程进行了研究。

At the same temperature, k〓 in the reversed micelles was always less than k'〓 in the buffer. According to the thermodynamic analysis for inactivation of penicillin amidase in the reversed micelles, the free energy of activation was increased by 2. 71%, while the entropies and enthalpies of activation were decreased, corresponding to 63. 9% and 76. 9% of that in pure buffer respectively.

由热力学分析可知,青霉素酰化酶在AOT/异辛烷反胶团中的热失活过程,与水溶液中相比,活化自由能△G〓增加了2.71%,而活化熵△S〓和活化焓△H〓分别减小为原来的63.9%、76.9%,从而使酶热稳定性平均提高了2~4倍。

With penicillin amidase entrapped in AOT/isooctane reversed micelles.

根据合理假设,建立了青霉素酰化酶在该耦合系统中水解PenG的反应动力学模型,与实验结果基本吻合。

A typical drug aminopyrine, in addition to levamisole, semi-synthetic penicillin may also cause.

典型药物是氨基比林,此外左旋咪唑、半合成青霉素也可引起。

Objective: To investigate the effect of ammonium oxalate on epilepsy of rats induced by penicillin.

目的:研究草酸铵对青霉素致大鼠癫痫模型的影响。

The medicine of antibiotic series raw material that is a delegate with p......

特别是以青霉素为代表的抗生素系列原。。。。。。

This method was sensitive and can be used for penicillin residue assay.

该方法灵敏度高,可用于青霉素残留量的测定。

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