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青蒿素

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One of the two major products was characterized by single crystal X-ray diffraction.Here the rings configuration in the crystal structure is described clearly by semi-quantitative ring puckering analysis.

用硫酸亚铁引发青蒿素的自由基裂解反应,对主产物之一的3-羟基脱氧青蒿素进行了单晶培养和X射线的表征,运用环Puckering分析方法对结构中环的构象进行了半定量描述。

G. SSA/Ro antigen expression and cytokine secretion etc. was involved in this phenomenon.

双氢青蒿素是抗疟药青蒿素的一种衍生物,具有一定免疫抑制作用。

The differentiation of U937 cells into more mature granulocytes was detected by nitro blue tetrazolium reduction test.

目的:通过青蒿素对经典人白血病细胞系U937的作用研究,探索青蒿素治疗白血病的可能。

FT-Raman, normal Raman spectra of artemisinin in solid state and surface-enhanced Raman scattering spectra of 1 ?10-5 mol/L artemisinin aqueous solution were recorded. 1756 Cm-1 hexat. lactonic ring vibration which was shown strong in FT-Raman and normal Raman spectra disappeared in SERS spectra. This phenomenon appeared to result from the broken of lactonic ring.

本文对固态青蒿素的FT-Raman光谱和普通Raman光谱以及低浓度(1×10^-^5mol/L)青蒿素水溶液的表面增强Raman散射光谱进行了检测,着重观察了1756cm^-^1六元内酯环振动谱带,发现其在FT-Raman和普通Raman光谱中表现为强振动,而在SERS光谱中此振动谱带消失,说明分子内酯环发生了破裂。

AIM: To investigate the effects of artemisinin on apoptosis and differentiation of classic human acute monoblastic leukemia cell line U937 and to study the possibility of treatment of leukemia with artemisinin.

目的:通过青蒿素对经典人白血病细胞系U937的作用研究,探索青蒿素治疗白血病的可能。

Extraction rate of artemisinin increased obviously with the decrease of dielectric constant of the mixed trichloromethane and dichloromethane, which was opposite to the results of mixed solvent of hexane and cyclohexane.

用正己烷、环己烷以及它们的混合溶剂作溶剂时,青蒿素的提取率随着溶剂的介电常数的增大而增大,而用二氯甲烷、三氯甲烷以及它们的混合溶剂作溶剂时,青蒿素的提取率随溶剂的介电常数的增大而减小。

To expand the usage dextrin(I3-CD) was prepared of artemisinin in animals, the inclusion complex of artemisinin with β-cyclo- according to the method we had established. The chemical characterization of the inclusion complex of Art with β-CD was identified by XRD and ^1HNMR in this study.

为了拓宽青蒿素在动物中的应用,扬州大学兽医学院临床兽医实验室制备了青蒿素-β-环糊精包合物,利用X射线粉末衍射和核磁共振氢谱(^1 HNMR)技术对该包合物的表征进行了鉴定。

A theoretical study on geometric structure of the Qinghaosu molecule has been Carried out by ab initio method of the Quantum Chemistry.

文章用量子化学从头算法,研究了青蒿素分子的几何结构,结果表明青蒿素分子的构型、键距、键角、二面角C1-O24-O23-C20等参数与X—射线分析测定值十分接近。

Methods A modle of DTH induced by dinitrofluorobenzene in mice was established and the effect of various concentrations of Qinghaosu, FK506 ,FK506 combined with Qinghaosu on DTH response were observed.

通过建立小鼠DTH模型,灌胃给药,给予不同浓度的青蒿素、FK506及青蒿素与FK506联合用药,观测其对小鼠DTH的影响。

Many people in the area have been using artemisinin alone, rather than in artemisinin combination therapies as recommended.

该地区的许多人正在仅仅使用青蒿素,而不是推荐的青蒿素联合疗法。

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