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This study provides a more useful and reasonable protocol with dihydroartemisinine for treatment the acute toxoplasmosis in clinic.

4本研究为双氢青蒿素临床治疗急性弓形虫感染提供了更具体、合理、有效的用药方案。

Objective To establish an HPLC-UV-ELSD method for determination of artemisinin and its related biosynthetic precursors in leaves of Artemisia annua.

目的HPLC-UV-ELSD联用建立黄花蒿叶片中青蒿素及其生合成相关倍半萜的含量测定方法。

Objective To synthesize 10-O-adipic acid-[2'-methoxy-4'-(3"-keto-1"-Butenyl)-Phenoxy-]-dihydroartemisinin conjugate.

目的 合成10-O-己二酸基-[2'-甲氧基4'-(3&-酮-1&-丁烯基)-苯酯]-双氢青蒿素酯。

ASES is 59% identical to Artemisia cyclase cDNA clone cASC125, 50% identical to epi-cedrol synthase from A. annua, 48% identical to amorpha-4, 11-diene synthase from A. Annua, 39% identical to the 5-epi-aristolechene synthase from tabacco, 38% identical to vetispiradiene synthase from H. Muticus, 41% identical to the δ-cadinene synthase from cotton. The coding region of cDNA was cloned into procaryotic expression vector pET30a and overexpressed in E. coli BL21 (DE3). The cyclase proteins extracted from bacterial culture were found largely in the insoluble protein fraction. The tissue specific expression patterns were analyzed by RT/PCR.

克隆的倍半萜合酶氨基酸序列与烟草马兜铃烯合酶、莨菪岩兰螺旋二烯合酶、棉花杜松烯合酶的一致性分别为39%,38%和41%;与青蒿柏木脑合酶、紫穗槐二烯合酶和一个推测的倍半萜合酶克隆cASC125的一致性为50%,48%和59%。cDNA编码区序列被克隆进原核表达载体pET-30a,并在大肠杆菌BL21(DE3)中诱导表达,但过量表达的蛋白主要是以不溶性蛋白形式存在。

Chromatinic margin was found in A549 cells after the dihydroartemisinin treatment. Apoptosis bodies could be found under the electron microscope.

双氢青蒿素作用于人肺腺癌A549细胞后琼脂糖凝胶电泳结果出现典型梯状带。

My company's main products: Rhynchophylline Gouteng silymarin (ethanol extract And no residual acetone) silymarin (water-soluble) silybin resveratrol daidzein emodin Suanzaoren extract of soy isoflavones curcumin, artesunate - Song Shupi extract, Hypericum perforatum extract, wild chrysanthemum extract, camptothecin, hawthorn extract, ursolic acid, corn required to extract, Maidong extract, garlic extract, ginsenosides, Chinese wolfberry extract - And asked Jing extract, green tea extract, the extract of small BAI Ju, Kushen extract, valerian extract, Salicylaldehyde glycosides, podophyllotoxin, Monascus Abulimiti of admission, puerarin extract, extract of astragalus, bitter melon extract Of, the thorn Tribulus terrestris extract, the extract of Ginkgo biloba leaves, Zhishi extract, Icariin, grape seed extract, Salvia extract yam extract, blueberry extract, the extract of Andrographolide, white Liu admission of Piti , Filed on Schisandra, Gynostemma extract, the extract of Angelica, Trifolium pratense extract, the extract of Rhodiola, soil Fritillaria saponins, Huang Chunju extract, and Cimicifuga extract, Hypericum perforatum Extract, Polygonum cuspidatum glycosides, genistein, reserpine, synephrine, sinomenine, Ciwujia glycosides, yam saponin, puerarin, peeling hormones, Kawa Ti of admission, lutein, lycopene, pumpkin seeds extract, licorice extract, nettle extract, the extract baicalin, Osthol, Asarum, saw Mr Brown extract, water Zaojiao extract, rutin extract, purple cabbage extract , Motherwort extract, Yanhusuo extract, hops extract, the extract of Magnolia officinalis, Cyclovirobuxine wood extract, Ban Langen extract, ginger extract, dandelion extract, senna extract, aloe extract , Dangshen extract, the extract of honeysuckle, quercetin, etc.

我公司主营产品:钩藤 Gouteng ·水飞蓟素·水飞蓟素·水飞蓟宾·白藜芦醇·大豆甙元·大黄素·大豆异黄酮·酸枣仁提取物·姜黄素,青蒿素松树皮提取物,连翘提取物,野菊花提取物,喜树碱,山楂提取物,熊果酸,玉米须提取物,麦冬提取物,大蒜提取物,人参总皂甙,枸杞提取物,问荆提取物,绿茶提取物,小白菊提取物,苦参提取物,缬草提取物,水杨甙,鬼臼毒素,红曲米提取物,葛根提取物,黄芪提取物,苦瓜提取物,刺蒺藜提取物,银杏叶提取物,枳实提取物,淫羊藿甙,葡萄籽提取物,丹参提取物,山药提取物,越橘提取物,穿心莲提取物,白柳皮提取物,五味子提起物,绞股蓝提取物,当归提取物,红车轴草提取物,红景天提取物,土贝母总皂甙,黄春菊提取物,黑升麻提取物,贯叶连翘提取物,虎杖甙,染料木素,利血平,辛弗林,青藤碱,刺五加甙,薯蓣皂素,葛根素,脱皮激素,卡瓦提取物,叶黄素,番茄红素,南瓜籽提取物,甘草提取物,荨麻提取物,黄芩提取物,蛇床子,细辛,锯叶棕提取物,水皂角提取物,芦丁提取物,紫甘蓝提取物,益母草提取物,延胡索提取物,啤酒花提取物,厚朴提取物,黄杨木提取物,板兰根提取物,生姜提取物,蒲公英提取物,番泻叶提取物,芦荟提取物,党参提取物,金银花提取物,槲皮素,等等

By various electroanalytical methods, the reduction of artemisinin took place at approximately 0.0V vs.

本文采用多种电化学方法研究了青蒿素分子中过氧基在Hg电极上的还原,还原电位在0.0Vvs。

Treatment with artemisinin-based combination therapy should be provided free of charge to the user in areas with falciparum malaria.

在恶性疟疾发病的地区,应该提供免费的青蒿素为主的综合治疗。

Treatment with artemisinin-based combination therapy should be provided free of charge to the user in areas with falciparum malaria.

在恶性疟疾发病的地区,应该免费提供以青蒿素为主的综合治疗。

However, the knowledge out of this work can be applied for the heterologous production of other valuable terpenoid drugs like the mentioned artemisinin or paclitaxel.

然而,知识出这方面的工作可以用于异种生产其他有价值的萜类药物一样,提到青蒿素或紫杉醇。

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