青蒿

TPS produces and sells pharmaceutical intermediates made from local resources, including L-dopa,Artemisinin ,artesunate, dihydro artemisinin, shikimic acid, mangiferin, camptothecin, star anise oil,ursolic acid , rosmarinic acid, anethole,etc.

产品有：左旋多巴，青蒿素，青蒿琥酯，双氢青蒿素，蒿甲醚，莽草酸，八角茴香油，芒果甙，喜树碱，熊果酸等当地资源生产加工的天然植物提取物。

The company mainly produces and sales of Products are: L-dopa, artemisinin, artesunate, dihydroartemisinin, shikimic acid, Star Anise Oil, Mangiferin, camptothecin, rosmarinic acid and other local resource production and processing of natural plant extracts.

公司主要生产及销售的产品有：左旋多巴、青蒿素、青蒿琥酯、双氢青蒿素、莽草酸、八角茴香油、芒果甙、喜树碱、迷迭香酸等当地资源生产加工的天然植物提取物。

Our company mainly production and sale of products are: L-dopa, artemisinin, artesunate, dihydroartemisinin, shikimic acid, mangiferin, Solanesol, camptothecin, Star Anise Oil, fans Diego Shannon acid and rosemary essential oils and other local resources for production and processing of pharmaceutical intermediates.

我们公司主要生产及销售的产品有：左旋多巴、青蒿素、青蒿琥酯、双氢青蒿素、莽草酸、芒果甙、茄尼醇、喜树碱、八角茴香油、迷迭香酸和迷迭香精油等当地资源生产加工的医药中间体。

The purpose of this study is petroleum ether (30℃-60℃) the optimum extraction of artemisinin-based research, as well as by ultraviolet-visible spectrophotometer in the artemisinin content of Artemisia annual samples.

本研究主要是对石油醚（30℃-60℃）提取青蒿素的最佳工艺的研究以及用紫外-可见分光光度计对青蒿中青蒿素含量的测定。

The results showed that different southernwood cultivars displayed different artemisinin contents, especially, the artemisinin contents of planting cultivars and the cultivars with coloured stem were higher. Further AFLP analysis indicated that a specific fragment was amplified respectively with the primers of EA04-MC05 and EA01-MC01. According to the differentia fragments, we clustering analyzed the 10 major kinds of southernwoods by utilizing WPGMA approach. However, there was no distinctly relativity between the artemisinin contents and diversity of AFLP analysis and just can distinguish, southernwood of Youyang county from Shapingba and Beipo in producing area which still illuminated that the heredity differentia of southernwood presented itself obviously in different area.

研究结果表明：不同的青蒿株系青蒿素含量不同，栽培株系和色茎株系青蒿素含量较高；进一步的AFLP分析表明引物组合EA04-MC05和EA01-MC01分别在高产青蒿株系和茎色青蒿株系中均能扩增出一条特异性条带；根据AFLP差异带，用WPGMA法对10个主要青蒿类型进行聚类分析，结果没有得到与青蒿素含量的明确关联，只是从产地上将酉阳青蒿与北碚、沙坪坝青蒿区分，说明不同地区青蒿的遗传差异较大。

Qinghao acid, Qinghao B, Scopoletin, Casticin and Chrysosplenol D had some antimalarial activities on P. berghei. Even when the dosage was up to 500 mg/kg/d, the maximal inhibition rate was only 59%, which is less active than QHS. Therapeutic effect of different ingredients of A.

青蒿酸、青蒿乙素、东莨菪内酯、青蒿黄酮1、青蒿黄酮2 5种成份对鼠疟均有不同程度的抑制作用，但剂量高达500mg/kg/d时，抑制率最高也仅达到59%，远低于QHS的疗效。

The ED50 and ED90 of QHS are (10.2±1.3) and (29.0±2.7) mg/kg/d respectively; and those of QHH (Qinghaosu:Qinghao acid:Qinghao B:Scopoletin=1:1:1:1) are (12.6±1.1) and (47.0±5.7) mg/kg/d respectively.

将青蒿素、青蒿酸、青蒿乙素、东莨菪内酯按1：1：1：1混合得到QHH，其ED50和ED90分别为(12.6±1.1)mg/kg/d和(47.0±5.7)mg/kg/d。

The invention relates to a method for producing duck wheat case pillow, wherein it is formed by duck wheat case, honeysuckle, and sweet wormwood; the mass ration between duck wheat case and Chinese traditional drugs is 10:1-3; the mass ratio between honeysuckle and sweet wormwood is 1:1; the duck wheat case is immerged in water for 2-3h; the honeysuckle and sweet wormwood are put in wood pot to be steamed for 11-12h; using microwave to dry matter to make water content lower than 8%; disinfecting.

本发明中一种苦荞壳药枕及其制备方法。由苦荞壳和中药材金银花、青蒿组成，苦荞壳与中药材重量比为10∶1～3，金银花与青蒿的重量比为1∶1。苦荞壳用水浸泡2-3小时，加入金银花与青蒿置于木甄薰蒸11-12小时，微波干燥含水量小于8％，杀菌即得。本发明的苦荞壳药枕对于失眠者和高血压、颈椎病、头痛、头昏等患者具有保健和辅助治疗作用。

Results Excepting Qinghaosu 50mg/kg/d group, The murine auricle weight difference of left and right 24hours after stimulation, the infiltration of mononuclear cell, the level of Interferon-gamma in serum and the expression of intercellular adhesion molecule 1(ICAM-1) were significantly decreased in the other groups of different concentrations of Qinghaosu, FK506 and Qinghaosu combined with FK506, as compared with control group, and the effect of Qinghaosu was related to the dosage within a certain dosage range.

结果 除青蒿素50mg／kg／d剂量外，青蒿素其它各剂量组、FK506与青蒿素联合用药组及FK506组与对照组比较，对照组的耳片肿胀程度、单一核细胞浸润程度、IFN-γ及ICAM-1的表达水平均明显高于其它各组，且有统计学意义(P＜0.05)。青蒿素在一定剂量范围内有一定的量效关系。

For this, he has built a metabolic pathway in yeast cells that synthesises a chemical called artemisinic acid which chemists can easily convert into artemisinin.

为此，他在酵母细胞内建立代谢途径，从而可以将这种酵母细胞合成为一种叫做青蒿酸的化学成分，而化学家们可以很容易地将这种青蒿酸转化为青蒿素。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。