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The complement-mediated bacteriolysis technique is useful for detection of cholera infection and state of infection. It can provide a basis for the immunological and epidemiological study of cholera.

补体溶菌试验法在基层霍乱检测工作中具有一定的应用价值,为霍乱的免疫学和流行病学研究提供了依据。

Objective To study the cholera vibriocidal antibody levels in different groups of people and the immunity state against cholera, and evaluate the complement-mediated bacteriolysis technique.

目的 了解不同人群的霍乱杀弧菌抗体水平和对霍乱的免疫状态,并探讨补体溶菌试验检测技术的应用价值。

This has important implications for the control of cholera , which will need to take into consideration

这对于控制霍乱有着重要的含义,因为控制霍乱需要考虑到两方面

Objective To investigate the difference of nucleotide sequence between cholera toxin of O139 and O1 Vibrio cholerae.

目的 探讨O139霍乱弧菌肠毒素核苷酸与O1群霍乱CTX毒素核苷酸序列异同。

The dynamic analysis of the antibiotic resistance surveillance for a long time can provide the basis for the epidemiologic studies on and the control of Vibrio cholerae.

长期对霍乱弧菌的耐药性进行监测和动态分析,可以为霍乱弧菌的流行病学研究以及对霍乱的监控和防治提供依据。

Both the potential of cholera to spread to new areas where there are susceptible populations causing large epidemics , as well as the need to control cholera in new areas of endemicity, such as parts of Africa and the Americas.

霍乱传播到存在易感人群的新地区而引起爆发流行的可能性和存在地方流行性的新地区如非洲、美洲的部分地区控制霍乱的需要。

From gentlefolk down to the very poor, were divided into two groups without their choice, and in most cases, without their knowledge; one group being supplied with water containing the sewage of London, and, amongst it , whatever might have com from cholera patients, the other group having water quite free from such impurity.

显然,没有实验能设计来说明水的供应对霍乱传播进程的影响,这个实验的范围也是最大的。不少于三百万人,男女老少,各个阶层,从绅士到穷苦人,在他们不能选择,且大多数是不了解情况的条件下,被分成了两组;一组喝含有伦敦污水的水,其中有来自霍乱病人的排泄物,另一组被供应绝对不含此类不净物的水。

If I had to choose between cholera and sitting through this movie again, Id choose cholera, its far less painful.

IMDB上有一个观众留言说,如果要我在霍乱和看完全片之间做出选择,我会选择霍乱

The results showed that the population administered with free adjuvant cholera vaccines,both low dose group and common dose group,occurred the weak adverse reaction with 10 ̄25% rate.The reaction rates between two dose groups of the same vaccine have not significant difference;The reaction rate of the first inoculation(19 ̄25%) is higher than those of the second inoculation(10 ̄15%)(P 05);The inoculating local reaction is very light ,only the very few subject occurred the scleroma with 15 mm of diameter.The reaction of aluminum absorbed cholera vaccine is slightly stronger than those of other groups.

结果表明,不加铝佐剂的O139型霍乱菌苗及O1群霍乱菌苗,不论是低剂量组(两剂全程接种45亿菌体)抑或常剂量组(全程接种90亿)接种人群均可产生10~25%的体温呈轻度升高的弱反应,并且同种菌苗的两剂量组的反应率无显著差异;第一剂接种的反应率(19~25%)较第二剂接种的(10~15%)高,P<0.05;接种局部反应轻微,只有个别受试者出现直径小于15mm的硬结;加佐剂的O1群吸附霍乱菌苗的反应较其它组强。

Vibrio cholerae adherence to and colonization in the small intestine are essential step in the pathogenesis of cholera. At least one type of pili, known as TcpA, is required for the colonization process. This paper reports the electron microscopic evidence showing that V. cholerae 01 and 0139 serogroups can express at least 4 types of pili when incubated at 28℃ on AKI agar or CFA (pH6.8). Among the four types, three can be expressed by classical and El Tor strains of Vibrio cholerae 01: TcpA pili are peritrichous,being 7-8nm in diameter, 5-10μm in length, and form bundles of parallel undulating filaments of 0.5-0.8 μm wide and 10-15μm long; Type B are 3-4nm in diameter, up to 2μm long, and of wavy morphology; Type C are 7-8nm wide and 0.5-0.8μm long.

本文通过电子显微镜对01群霍乱弧菌古典生物型和El Tor生物型以及0139群霍乱弧菌研究发现,在培养基AKI和CFA(pH6.8)28℃培养条件下,01群EVC和CVC均可产生TcpA,B型和C型菌毛;0139群霍乱弧菌可产生TcpA和B型菌毛,与01群一致。

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