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The fact that Monascus productscontaining higher content of citrinin is a new challenge to the food safety.

数年前,桔霉素的研究在国内是个空白,我国红曲产品桔霉素的现状,对食品安全提出了新的挑战,对此我们无法回避,积极应对已成为红曲行业的共识。

However, in 1995 professor Blanc found that there was a mycotoxin citrinin in RFR, which triggered a controversy about the safety of RFR in the world.

然而,1995年法国Blanc等发现红曲中含有真菌毒素桔霉素,从而使红曲的安全性受到国际社会的广泛关注,控制红曲中桔霉素的含量成为当今红曲的研究热点之一。

Avilamycin quality have what kind of quality , the existing returns will help to alter or decorate it's molecule by the Combinatorial biosynthesis method , and produce new ramification of Avilamycin .

阿维拉霉菌是一种什么性质的抗生素,现有的研究成果将有助于采用组合生物合成方法进行阿维拉霉素的分子改造与修饰,从而产生新的阿维拉霉素衍生物。

The results show that the dispersity of emulsion is good and the average diameter of particles is about 15 nm. Its bactericidal properties to some bacteria and epiphytes are strong under daylight lamp irradiation. The killing rate to Gram negative bacterium (Staphylococcus aureus and Bacillus subtilis) is 100%, in addition, killing activity of it to Gram positive bacterium is very high. It has a clear antibacterial circle of about 20 mm in diameter toward epiphytes such as Aspergillus niger, Aspergillus flavus and Candida albicans etc.

结果表明,混晶乳液分散性好,粒径约15nm;在普通日光灯照射下,乳液对一些细菌和真菌有很好的抗菌性能:对革兰氏阳性菌(金黄葡萄球菌和枯草芽孢杆菌)的杀灭率达到100%,对革兰氏阴性菌也有很好的杀灭性能,对黑曲霉、黄曲霉和白色念珠菌等真菌产生清晰的抑菌圈,抑菌直径约20mm。

The carbon and nitrogen sources could satisfy the basic growth requirement of Geotrichum candidum link However, since its ability of utilizing starch and dextrin is not strong, the best pre-treatment of the waste water is sacchrification.

小麦淀粉废水的碳氮源能够满足白地霉生长的基本要求。但白地霉利用淀粉和糊精的能力并不强,因而最适的废水预处理方法是经过糖化。

Methods Genomic DNA was extracted from 50 strains of S.schenckii, including 49 clinical isolates and 1 referrence strain, as well as from 1 strain of Mucor, Aspergillus fumigatus and Candida albicans, respectively, as controls. Four primers were designed according to previous studies, and screened by PCR.

以50株不同地区来源的孢子丝菌临床分离株及标准株的基因组DNA作为研究样本,以毛霉、烟曲霉、念珠菌临床分离菌株基因组DNA作为对照,通过特异引物PCR扩增的方法筛选国内外文献中报道的4对孢子丝菌引物。

Traditional natural isolation, mutation and selection, rational screening and protoplast fusion have made a great progress in the improvement of both Penicillium chrysogenum and Cephalosporium acremonium, two main industrial strains for production of P-lactam antibiotics.

在增加产量和大幅度地降低生产成本方面,最主要的β-内酰胺抗生素生产菌,产黄青霉和顶头孢霉(Acremonium chrysogenum or Cephalosporium acremonium)的菌种改良和发酵工艺的优化得到卓有成效的发展。

The pathogenic bacterium of prepartum and intrapartum infectious pneumonia mostly were G- bacilli,the pathogenic bacterium of postpartum infectious pneumonia mostly were G- bacilli and staphylococcus aureus.6.The drug resistant rates of G- bacteria to penicillins,cephalosporins,and monocyclicβ-lactam antibiotic were high,However,their compound of addingβ-lactamase inhibitor agents was relatively low resistance,and all G- bacteria were sensitive to carbapenem antibiotics.

产前及产时感染性肺炎的病原菌以G-杆菌多见,而产后感染性肺炎的病原菌主要为G-杆菌和金葡菌。6.G-菌对青霉素类、头孢菌素类及单环类的β内酰胺类抗生素耐药率高,但对其添加β内酰胺酶抑制剂的复合制剂耐药率较低,对碳青霉烯类抗生素均敏感;金葡菌对苯唑西林耐药率低,对万古霉素均敏感。7。

Methods: The inhibitation of HL-60 cells by Rapamycin was measured by MTT assay. Morphic change of the apoptosis of HL-60 cells was observed by inverted microscope and light microscope, trapezoid straps by DNA agarose gel electrophoresis, and apoptosis rate by flow cytometry. Western-blot analysis was performed to detect the expression of Bax and Bcl-2 proteins after rapamycin treatment.

用MTT比色法测定雷帕霉素对HL-60细胞增殖的影响;用倒置显微镜和荧光显微镜观测细胞凋亡的形态学改变;DNA琼脂糖凝胶电泳观测凋亡的梯形条带;流式细胞仪检测细胞凋亡率;Western-blot检测HL-60细胞经雷帕霉素处理后,Bax、Bcl-2蛋白的表达情况。

It was recently reported in Japan that effective component of the extract of Rubia Cordifolia L has obvious inhibition for leukemia, cancer of colon and carcinoma of the lung in mice, its curative effects equaled or exceeded to the catharanthine, mitomycin and adriacin and had less virulence for normal cells.

近来日本学者系川秀治等研究发现茜草提取物中的有效成分环己肽类化合物对小鼠的白血病、腹水癌、大肠癌、肺癌均有明显的抑制作用,其疗效等于或优于长春碱,丝裂霉素、阿霉素,并且对正常细胞的毒性低。

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