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Objective: To determine the content of diethylstilbestrol and testosterone in HY-LINE Variety Brown chick embryo and egg.

目的:建立了RP-HPLC法测定鸡胚蛋及鸡蛋中己烯雌酚、丙酸睾酮激素残留。

OBJECTIVE: To observe the influence of diethylstilbestrol combined with EPF on metabolic biochemical indexes and bone histomorphometry of lumbar and femur in ovariectomized rats.

目的:观察己烯雌酚与淫羊藿总黄酮联合用药对去卵巢大鼠腰椎和股骨的代谢生化指标和骨组织形态计量学的影响。

Objective To establish a prolactinoma model induced by diethylstilbestrol in female Wistar rats, and study the effects of rosiglitazone on rat prolactinoma.

目的 采用乙烯雌酚诱发方法建立垂体催乳素腺瘤模型,研究罗格列酮对PRL腺瘤的影响。

Methods: The serum estrin (E2), progestogen, follicule stimulating hormone and luteotropic hormone were measured in 15 patients with hysterectomy, 22 patients with uterine arterial embolization and 29 normal persons, respectively.

对15例子宫切除患者、22例子宫动脉栓塞患者和29例正常人分别测定血清雌二醇、孕酮、卵泡雌激素和黄体生成素。

Methods The microorganism of macula retinae on s kin lesion in 26 male patients and the serum follicular-stimulating hormone,lateinizing hormone,progestrong and estriol prolactin in 25 men were st udied with quantitive, positioning, qualitative and radio-immunitive methods, a nd then compared the results with those of the healthy men.

分别用定量、定位、定性和放射免疫学方法对26例男性黄褐斑患者皮损区微生态和25例血清卵泡刺激素、孕酮、雌三醇(E3)、黄体生成激素及催乳激素的水平进行研究,并将其结果与健康男性面部菌群、血清性激素水平加以比较。

In order to study the mechanism by which estrogen effects on bone, the effect of estrone on expression of c-myc protein in the epiphyseal plate of fetal mouse long bone was detected by immunohistochemistry procedure in vitro.

为初步探讨雌激素对骨的作用机制,以体外培养的小鼠胚胎长骨作为模型,通过免疫组织化学方法检测雌酚酮对骺板静止区、增殖区和肥大区c-myc蛋白表达的影响。

Firstly adopting DCC and SP method to detect ER expression in bone tissue, results showed that XW630 can significantly promote ER expression in bone tissue and increase the content of ER, which is super than estrone.

本研究首次应用DCC法和SP法直接对大鼠骨组织中ER的表达进行了测定,其结果显示:XW630具有促进组织中ER表达的作用,可以明显地增加ER含量,其作用优于雌酚酮。

Results:Compared with control,the re were significant increase in bones length and length of their diaphyses after treated with 10-7 mol/L estrone.

16 d胎龄雌性小鼠尺骨在含有雌酚酮的BGJb培养基中旋转培养48 h后,测量骨总长和骨干长度;H.E染色,光镜下计数破骨细胞和肥大软骨细胞。

Estrone stimulates bone formation and inhibites bone resorption in vitr o.

雌酚酮在体外可抑制骨吸收,促进骨形成。

Results of histology, SEM and three-point bend biomechanical competence demonstrated that XW630 has promoting osteogenic action obviously. The effects of XW630 for prevention and treatment of osteoporosis and osteoporostic fracture were effectively and much better than estrone.

组织学、扫描电镜及三点弯曲力学测试结果表明:XW630具有促进成骨的作用,可以有效地预防和治疗骨质疏松症及骨质疏松性骨折,其作用优于雌酚酮。

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