难

English is the world's 3,000 languages A, belong to Indo-European languages, the Germanic languages of the West Germanic language group (including German, Dutch, Fleming Flemish language, Frisian language and English).

Brief History of English 难是难，想学的话，应该很快！英语是全世界三千多种语言的一种，属于印欧语系、日耳曼语支中的西日耳曼语群（包括德语、荷兰语、弗来芒语、弗里西亚语和英语）。

Advance basic research has confirmed that the alkaloids extracted from thunberg fritillary bulb which is widely used in clinical medicine in vitro and in animal experiments have reversed MDR of leukemia. It will increase resistance of acute leukemia cells anticancer drug concentration and lower resistance the expression of Pgp. Pre-Clinical Experimental Research also shows that the conventional chemotherapy combined with the powder of thunberg fritillary bulb for the treatment of acute leukemia. Clinical complete response rate was higher, especially for patients with refractory or relapsed leukemia patients better clinical remission rate. In addition, Caladium particles Slices with chemotherapy in the treatment of RAL Clinical studies also show the Chinese refractory leukemia improve clinical efficacy safe and reliable.

先期基础研究已证实：临床常用的化痰散结中药浙贝母提取的生物碱体外及动物实验均有逆转白血病多药耐药的生物活性，能增加耐药的急性白血病细胞内抗癌药物浓度，降低耐药蛋白Pgp的表达；临床预实验研究也表明，常规化疗方案配合浙贝母粉用于急性白血病临床治疗，其临床完全缓解率明显高于对照组，尤其对难治及复发白血病患者临床缓解率更佳；此外，单药浙贝母颗粒配合化疗治疗RAL的临床研究亦显示中药在提高难治性白血病临床疗效方面安全可靠。

Objective To solve the problem with the sterilization and storage of Vaseline gauze.

目的 解决凡士林纱布灭菌难、保管难的问题。

Likes a person being very difficult, to give up the oneself belovedperson be more difficult.

爱一个人很难，放弃自己心爱的人更难。

No He won't have it , he knows his whole back city's ropes It don't matter, he's dope He knows that, but he's broke He's so stacked that he knows When he goes back to his mobile home, that's when it's Back to the lab again yo This whole rap shit He better go capture this moment and hope it don't pass him You better lose yourself in the music, the moment You own it, you better never let it go You only get one shot, do not miss your chance to blow This opportunity comes once in a lifetime yo The soul's escaping, through this hole that it's gaping This world is mine for the taking Make me king, as we move toward a, new world order A normal life is borin, but superstardom's close to post mortar It only grows harder, only grows hotter He blows us all over these hoes is all on him Coast to coast shows, he's know as the globetrotter Lonely roads, God only knows He's grown farther from home, he's no father He goes home and barely knows his own daughter But hold your nose cuz here goes the cold water His bosses don't want him no mo, he's cold product They moved on to the next schmoe who flows He nose dove and sold nada So the soap opera is told and unfolds I suppose it's old potna, but the beat goes on Da da dum da dum da da You better lose yourself in the music, the moment You own it, you better never let it go You only get one shot, do not miss your chance to blow This opportunity comes once in a lifetime yo No more games, I'ma change what you call rage Tear this mothafuckin roof off like 2 dogs caged I was playin in the beginnin, the mood all changed I been chewed up and spit out and booed off stage But I kept rhymin and stepwritin the next cypher Best believe somebody's payin the pied piper All the pain inside amplified by the fact That I can't get by with my 9 to 5 And I can't provide the right type of life for my family Cuz man, these goddam food stamps don't buy diapers And it's no movie, there's no Mekhi Phifer, this is my life And these times are so hard and it's getting even harder Tryin to feed and water my seed, plus See dishonor caught up bein a father and a prima donna Baby mama drama's screamin on and Too much for me to wanna Stay in one spot, another jam or not Has gotten me to the point, I'm like a snail I've got to formulate a plot fore I end up in jail or shot Success is my only mothafuckin option, failure's not Mom, I love you, but this trail has got to go I cannot grow old in Salem's lot So here I go is my shot.

无 他不会有，他知道他的整个回城的绳索它不处理此事，但他的涂料他知道，但他的突破他的，所以堆叠他知道当他回到他的手机在家，就什么时候，它的回到实验室又摇摇这整个说唱为Shit 他最好去捕捉这一刻，并希望它不通过他您更好地失去了自己在音乐，时刻你拥有它，你最好永远不会放手你只能获得一杆，千万不要错过你的机会，以打击这个机遇而来的一生中只有一次的心灵灵魂的逃亡，透过这个洞，它的溃烂这个世界是矿井为录取令我国王，因为我们走向一个新的世界秩序过正常的生活，是borin ，但superstardom的接近邮政砂浆它不仅日益困难，只有长大白热化他的打击我们所有这些锄头，是所有对他的海岸到海岸的表演，他知道作为globetrotter 寂寞的道路，只有上帝知道他的成长到离家远，他的父亲并没有他回家，勉强知道自己的女儿但对于你的鼻子cuz这里有云冷水他的老板不希望他没有谟，他的冷战产物他们转移到下一schmoe谁流向他的鼻子鸽派和出售纳达所以肥皂歌剧是告诉，并逐步落实我想它的旧potna ，但在街上巡逻下去大达达姆弹达达姆弹达大您更好地失去了自己在音乐，时刻你拥有它，你最好永远不会放手你只能获得一杆，千万不要错过你的机会，以打击这个机遇而来的一生中只有一次的心灵没有更多游戏，我是改变你们称之为愤怒催泪这mothafuckin屋顶起飞一样二日犬笼我是playin在beginnin ，心情，一切都变了我是咀嚼起来，吐出一片嘘声起飞阶段但我一直rhymin和stepwritin未来的CYPHER 最好相信有人的payin该pied伯尔所有的痛苦内扩增事实我不能得到我的9至5月我不能提供适当类型的生命，因为我的家庭 cuz男子，这些goddam粮票不买尿布它的不看电影，有没有mekhi phifer ，这是我的生命这些时代，所以很难和它变得更难 tryin到饲料和水我的种子，加上见荣辱赶上了bein父亲和表面唐娜宝宝妈妈戏剧的尖叫和太多，我想留在现场的一个，另一个果酱或不得到了我的一点，我想蜗牛我必须制订一项阴谋前列我结束了在监狱或打针成功是我唯一的mothafuckin选择，失败的不是妈妈，我爱你，但这个线索已经去我不能老在塞勒姆的地段所以在这里，我去的是我的了一枪。

The current dilemma of the current academic quality, academic ethics and academic research makes it impossible for critics to give and receive criticism with heartsease and therefore it is difficult for them to devote themselves to academic research.

一言以蔽之，在正常的学术批评日渐稀缺时，批评容易陷入"一捧就笑、一骂就跳"的困局；在当前的学术品质、学术道德和学术研究泥沙俱下之际，在重大课题的申报与重大利益挂钩时，当事人就很难心平气和地接受批评，当然也很难潜心做学问、搞研究。

The public, especially in low-income people is very difficult to buy a house, the public housing consumption does not start up, real estate, it is difficult to achieve a virtuous circle.

市民，尤其是在低收入的人是很难买房子，市民住房消费没有启动，房地产，这是很难实现良性循环。

Two sorts of callings have appeared to me hard and dangerous: a merchant is hardly free from negligence: and a huckster shall not be justified from the sins of the lips.

有两件事，依我看来，又难又危险，那就是：商人很难不犯罪，店员难免不失言。

A reciprocal metabolism pattern was represented between cortices and paralimic regions, which implicated a reciprocal dysfunctional changes of paralimic-cortex pathway in patients with TRD. Cerebellar hypermetabolism suggested hyperfunctional changes of cerebellum under depressed condition. Frontal white matter hypermetabolism implicated further studies on potential structural abnormalities of cerebral regions in TRD.

难治性抑郁症患者存在旁边缘系统代谢增高和皮质代谢降低的交互性代谢改变模式，支持抑郁症边缘系统－皮质功能紊乱假说；患者小脑代谢水平增高，提示抑郁状态下小脑功能亢进；额叶白质高代谢水平提示有必要对难治性抑郁症潜在的脑结构异常改变进行深入研究。

Especially, for some persons who are ill-tempered. They are impossible to do it, or it's very difficult to do it.

特别是那些脾气暴躁的人，他们不可能做到的，或者很难很难做到。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。