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Phage display of recombinant human lymphotoxin mutation librariesand receptor affinity screeningContraction of conformable large molecule mutation library is pivotal for molecular evolution study in vitro. In order to extend the range of the screening region of amino acid in LT gene, several receptor binding sites of LT were mutated randomly by overlap PCR amplification with the random nucleotide primers, the R46, S106, L130 combined site-directed random mutation library and R46~A52, S106~F110, R46~A52 + S106~F110 region random mutation libraries of rhLT were constructed successfully.

二。重组人淋巴毒素噬菌体库的构建及受体亲和筛选构建适合的大容量生物大分子变异体文库是进行体外分子进化研究的关键,为了扩大LT基因序列中被筛选的氨基酸范围,我们采用含随机核苷酸序列的引物,通过Overlap PCR的方法对LT的受体结合区域进行多点随机突变,分别构建了rhLT R46+S106+L130三点随机突变组合文库和R46~A52、S106~F110、R46~A52+S106~F110区域随机突变体库。

Considering the randomness of the structural physical parameters and utilizing the random variable's functional moment method and the algebra synthesis method, the mean value and the variance of the mean square value of the structural displacement response under stationary random excitation are computed firstly from the expressions of structural stationary response in frequency domain. And then the expressions of the mean value and the variance of stochastic rigid frames dynamic reliability are educed from the Poisson formula of calculating dynamic reliability.

考虑结构的物理参数具有随机性,从结构随机响应的频域表达式出发,利用求解随机变量数字特征的代数综合法和矩法,导出随机参数刚架结构在平稳随机激励下的位移及速度响应均方值的数字特征,再由动力可靠性的Poisson公式导出结构动力可靠度的计算公式。

This paper study the character and application of the solution of BSDE, the main results include: for the second kind of BSDE, the existence and uniqueness of the solution under non-Lipschitz condition, comparison theorem and stability are established , under weaker condition , the existence of the minimal and maximal solution is proved and the application in stochastic control and utility function is given; for the first kind of BSDE, under weaker condition , the existence of minimal and maximal solution .stability, comparison theorem and application to utility function are proved.

本文研究倒向随机微分方程解的性质及其应用,主要结果有:针对第二类方程,讨论了在非Lipschitz条件下倒向随机微分方程解的存在唯一性,比较定理及稳定性等,在更弱条件下,得到了倒向随机微分方程的最大解和最小解的存在性,在此基础之上,给出了在随机控制及效用函数方面的应用;针对第一类方程,同样在较弱条件下,证明了方程最大、最小解的存在性、稳定性、比较定理及其在效用函数的应用。

This paper study the character and application of the solution of BSDE, the main results include: for the second kind of BSDE, the existence and uniqueness of the solution under non-Lipschitz condition, comparison theorem and stability are established , under weaker condition , the existence of the minimal and maximal solution is proved and the application in stochastic control and utility function is given; for the first kind of BSDE, under weaker condition , the existence of minimal and maximal solution .stability, comparison theorem and application to utilityfunction are proved.

本文研究倒向随机微分方程解的性质及其应用,主要结果有:针对第二类方程,讨论了在非Lipschitz条件下倒向随机微分方程解的存在唯一性,比较定理及稳定性等,在更弱条件下,得到了倒向随机微分方程的最大解和最小解的存在性,在此基础之上,给出了在随机控制及效用函数方面的应用;针对第一类方程,同样在较弱条件下,证明了方程最大、最小解的存在性、稳定性、比较定理及其在效用函数的应用。

The primitive polynomial of 3-12 pseudo-random sequence generator is obtained after the deductions. The better nonlinear feedback function of all states pseudo-random sequence generator can be picked out according to the characteristic of pseudo- random sequence signal, then using all states of shifting counter through modifying the linear shift register feedback network to realize the all states pseudo-random sequence signal.

经过推导可以得到3-12 bit伪随机序列发生器的本原多项式,再根据伪随机序列信号的特性选择出较好的全状态伪随机序列发生器的非线性反馈函数,即通过修改线性移位寄存器的反馈网络将移位型计数器的全部状态加以利用,实现全状态伪随机序列信号。

By producing pseudorandom number series, we rectify the power spectrums of normal random inputs in the same shape as power spectrums of simulating signals. Through Laplace transformation, we can acquire the frequency response functions of rectifier. Two simulating examples were presented. The power spectrum curves based on one peak function model were almost coincided with the power spectrum curves of simulating loads shown in the figures. Simulating results of input loads had good accuracy. Creating a simulating method and program of input load in this paper was effective.

本文利用随机过程仿真的一般理论在已知随机载荷的分布特性、均值、方差和功率谱函数以后,实现随机载荷的计算机仿真,即利用仿真技术得到符合已知载荷的分布特性和功率谱特性的随机载荷的时间序列。1 产生伪随机数序列及分布整形采用乘同余法产生伪随机数的递推公式为[2 ] :yi+1 =λyi ( 1 )式中M =2

Firstly, the random walk problem is introduced and the solution is schemed out theoretically. And then, the equivalent RC circuit for thermal analysis is discussed as the IC package is divided into many small blocks at the desired level of granularity. The techniques of analyzing the equivalent RC network by random walk algorithm are then discussed. At the same time, an equivalent model for thermal analysis is set up according to an IC chip. The proposed method is then applied to this model for both steady and transient analysis. Two speedup strategies, pseudo parallel walking and walk results reuse, are proposed sequentially to improve the algorithm performance.

首先简述随机行走问题的基本概念,给出问题的理论解法;然后讨论基于三维网格划分的IC芯片热等效阻容网络模型,着重分析随机行走算法在热等效模型中的应用,并建立一个实际芯片的热等效模型,采用随机行走算法模拟计算模型的稳态温度分布和瞬态温度变化;最后针对随机行走算法应用中的不足,提出了伪并行行走和结果重用2种加速技术。

Firstly, an empirical approximation model of stochastic programming is obtained by replacing the probability measure of original program with empirical probability measure. Sequentially, the constrained stochastic programming is transformed into an equivalent unconstrained stochastic programming. Finally, using the epi-convergence theory, the almost everywhere upper semiconvergence of optimal solution set of empirical approximations for stochastic programming is obtained.

首先通过经验概率测度替代初始规划的概率测度得到随机规划的经验逼近模型,然后将带有约束的随机规划问题转化成与其等价的无约束的随机规划问题,最后利用上图收敛性理论,给出了随机规划经验逼近最优解集的几乎处处上半收敛性。

A new data management algorithm for anycast based random sampling in sensor networks;2. Composite random sampling algorithm for scheduling concurrent projects;3. In the existing methods of random summing of total resource,the shape of the total resource curve sometimes distributes skewly,in view of which,the new method was put forward to improve random sampling .

针对现有的资源总量随机求和中存在的资源总量曲线形态有时呈偏态分布的问题,提出了对其随机抽样方法的改进方案,即把随机抽样入口由原来定义在(0,1)区间上改为定义在(0,ki)区间上(ki为第i个局部地质单元的石油资源量保险系数),利用(0,ki)区间上均匀分布的随机数对风险分析后的资源总量分布函数进行随机抽样。

Based on the idea and technical in the references[16],[17]and[26]as well as the theories of martingale,Brownian motion and stochastical orders,the expectation of present value of annuities with controlled random interests is obtained,and the upper bounds of present value function of discrete stochastic annuities with random interests in sense of convex order are derived,and the numerical characteristics of upper bounds are also obtained,furthermore,the expec

基于文[16],[17]和[26]的思想方法以及鞅、反射Brownian运动和随机序的理论,得到了控制随机利率下连续年金现值的期望,并给出了离散随机年金现值函数在凸序意义下的上界,讨论了上界的分布函数和停止损失保费,进而得到了离散的随机年金现值的期望。

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