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Results: In comparison with adriamycin group, myocardial contractibility and coronary fluence were improved and arrhythmia was reduced in FDP and CoQ10 groups, especially in FDP group.

结果:FDP与CoQ10均可改善阿霉素引起的大鼠心肌收缩幅度、冠脉流量下降,减少心律失常的发生,降低冠脉流出液中CPK活力,且FDP优于CoQ10。

Reversed-phase high performance liquid chromatography was developed to quantify the content of DOX in rate plasma and mice tissues.

建立了高效液相色谱测定阿霉素在血浆样品和组织样品中含量的方法。

Combined with DOX, the suppression and apoptosis could be significantly enhanced.

TRAIL能有效抑制RKO的生长,联合阿霉素后,其对RKO的生长抑制作用及凋亡诱导作用均明显增强。

Cell growth and apoptosis were measured by MTT method and flow cytometry. TRAIL gene expression before and after combination with DOX was measured by RT-PCR.

将重组腺病毒载体介导的TRAIL基因作用于大肠癌细胞株RKO,并联合低剂量的阿霉素协同作用。

Artesunate could inhibit the proliferation and induce apoptosis in K562 and K562/DOX cells in vitro.

阿霉素联合青篙琉酷对KS能/DOX细胞具有协同抑制作用,并增加K562/DOX细胞的凋亡率。

Cell growth and apoptosis were measured by MTT method and flow cytome-try. TRAIL gene expression before and after combination with DOX was measured by RT-PCR.

将重组腺病毒载体介导的TRAIL基因作用于大肠癌细胞株RKO,并联合低剂量的阿霉素协同作用。

The results indicate that A54 can improve the cytotoxicity of DOX to malignant hepatocytes and decrease the side-effect of DOX to normal hepatocytes.

实验结果表明A54能够提高阿霉素对肿瘤细胞的毒性并降低对正常肝细胞的毒副作用。

Objective : To observe the effects of adriamycin and taurine on smooth muscle of duodenum of rabbits.

目的:观察阿霉素和牛磺酸对肠平滑肌自动节律性的影响。

The results showed: there were some apoptosis cells found by microscope, electron lens and flow cell counter; there were model gradient streak in DNA electrophoresis of the GCT cells effected by high dense ADM over 0.4

结果表明,光镜、电镜及流式细胞分析均可获取一定数量的凋亡细胞,且较高浓度(0.4μg/ml以上)阿霉素处理的细胞DNA电泳可见典型的梯形条带。

Objective To find an ideal method for managing local tissue damage caused by extravasation of pharmorubucin.

目的探讨不同疗法对表阿霉素外渗后局部组织损伤修复的理想方法,为临床护理提供依据。

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