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The diarrhea frequencies and the diameters of egesta of the mice fed on opioid peptides in filter papers were decreased significantly (P.05), under feeding conditions, there is less diarrhea than that under fasting conditions, there is a obvious difference between sample group and controlled group.

饥饿状态下测定的粪便水圈直径结果表明,阿片肽组小鼠粪便在滤纸上的水圈直径比对照酵母组显著降低(P.05)。进食状态下试验各组的腹泻程度比饥饿状态下都有所降低,灌胃阿片肽2mg/只组与对照酵母组之间有显著差异(P.05)。

It was showed that the motion of independent ileum of rat was affected by the expressed opioid peptides.

用RT-PCR的方法研究了重组阿片肽对大鼠小肠阿片受体表达的影响。

Malanga etc by the activity that GABA inhibition of opioid etc, and is confirmed with echors exist on the function of opioid GABA synergistic action.

Malanga等发现GABA的活性受到阿片类物质的抑制,而Echo等则证实阿片与GABA存在功能上的协同作用。

These kinases play an important role in the signal transduction of opioid receptors, tolerance and dependence of opiate.

它们在阿片受体的信号传导、阿片类药物的耐受性、依赖性等方面起重要作用。

It was studied that the function of opioid peptide on the expression of opiate receptor gene in small intestine of rats by RT-PCR.

用RT-PCR的方法研究了重组阿片肽对大鼠小肠阿片受体表达的影响。

Comparisons between oxytocin-induced antinociception in different hyperalgesic models The order of antinociceptive effects induced by intrathecal administration of OT is: in normal rats, in rats with inflammation, in rats with ligation .

这些结果提示,在正常及炎症痛大鼠,催产素系统和阿片系统彼此参与介导对方的镇痛效应;而在神经损伤性痛大鼠,催产素系统和阿片系统在痛觉调制上是相对独立的。

Natrexone hydrochloride is used in clinic to refrain from addiction caused by meconium drugs. In addition, methylnaltrexone is used to cure meconic intestines dysfunction, and its clinical research is already in period III presently. Although they all possessed broad market, to our best knowledge, their mature production processes have not been reported.

盐酸纳曲酮用于临床戒除阿片类毒品的成瘾性,甲基纳曲酮用于治疗阿片性肠功能失调,其临床研究已经处于Ⅲ期,两者具有广泛的市场,但两者成熟的生产工艺尚未见文献报道。

It seems that the endogenous opioid peptides may exert an inhibitory role on NA release in the preoptic area during AA.

上述结果提示针刺镇痛时视前区的内阿片肽通过阿片受体,抑制该区NA的释放。

The results suggest that ACTH〓 can also antagonize the μ-opioid analgesia at the supraspinal level, without changing the basal pain shreshold.

结果提示,〓在脊髓以上水平也可对抗阿片镇痛作用,而且对μ型阿片受体介导的镇痛具有明确的拮抗效应。

Opiates are one of the most widely abused illegal drugs in the world and especially used in its traditional regions in Asia.

阿片类物质是全球尤其是亚洲最常见的违法滥用药物之一,在我国滥用的阿片类物质主要是海洛因和吗啡。

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