阻滞药

Methods: Separate and abstract the effective components of Huangqi (Omni-Saponin、total-flavone) and Danshen (Danshen-ketone、 Danshen-Quinone). Applying L-Arginine methyl ester to pregnant rats by I. P to make Nitrogen Oxide Synthesis blocking models (uterus-placenta-fetus lacking blood and oxygen model or pregnant hypertension syndrome model). On day 12, 18 of pregnancy paunched the rats and took out the fetus and placenta/uterus. Measured the basal BP during pregnant period and BP、protein、basal activity each day. Observed placenta/deciduas ultramicroscopic structure by electron microscope and took count of languishment cells. Measured the expressive intensity of bcl-2、Bax of placental nutrient cells by SABC method.

一氧化氮合成酶阻滞剂L-精氨酸甲酯妊娠大鼠腹腔给药，制作一氧化氮合成阻滞模型（子宫-胎盘-胎儿缺血缺氧或妊娠高血压模型），妊娠第12、18天剖腹取胎、胎盘／子宫，妊娠期测基础血压，每日测血压、蛋白质量、基本生理活动；电镜观察胎盘／蜕膜超微形态结构，并进行细胞凋亡计数；免疫组化检测胎盘滋养细胞bcl-2、Bax表达强度；原位杂交法检测胎盘滋养细胞、血管内皮细胞VEGF、eNOS、iNOS、MCP-1、MMP9（基质金属蛋白酶9）mRNA表达。

Methods We adopted four methods that single cpidural block anesthesia or narcotics analgesies were injected into subarachnoid space and epidural space or single narcotics was injected into subarachnoid space (group C fentanly 25μg;group D fentanly 20μg) to study analgesia birth for 130 nullipara women. The analgesia efficacy, side effect, birth time md mode,postpartum haemorrhage and the condition of the fetus and the newborn were compared.

采用单纯硬膜外腔阻滞、蛛网膜下腔-硬膜外腔联合给予低浓度麻醉药及镇痛药、单纯蛛网膜下腔给予低浓度镇痛药(C组芬太尼25μg，D组芬太尼20μg)等四种不同的方法对130例初产妇进行分娩镇痛，比较几组的镇痛效果、不良反应及对产程、分娩方式、产后出血、胎儿及新生儿等的影响，并与40例正常未干预组产妇比较。

We evaluated the systemic and local effects of clonidine as an analgesic adjunct to psoas compartment block with levobupivacaine.

作者评估了可乐定辅助于左旋布比卡因腰大肌间隙阻滞时全身给药和局部给药的效果。

In acute experiments, APO-induced stereotypy and locomotion could be blocked by both selective 〓 antagonists SCH 23390 and 〓 antagonist sulpiride, and they had a synergistic effect when used in combination.

急性实验中，选择性〓阻滞剂SCH 23390和〓阻滞剂舒必利能有效地对抗APO诱发的定型活动和肢体运动，两药相加有协同作用。

Results］In 108 patients (93.1%) routinely took antiplatelet drug orally;75 patients (64.7%) common took ACEI orally; 82 patients (70.7%) usually took beta-blocker orally; only 39 patients (33.6%) insisted on taking lipid-lowering drug orally;26 symptomless patients long-term took orally nitrate;24 symptomless patients long-term took Calcium antagonists.

结果］ 108例（93.1％）患者常规口服抗血小板药物，存在主要问题是部分患者用量偏低；75例（64.7％）患者服用ACEI；82例（70.7％）患者常规口服β-受体阻滞剂，心率达标率为39％；只有39例（33.6％）患者坚持服用调脂药；26例患者无症状长期口服硝酸酯类药物；24例患者长期口服钙通道阻滞剂。

We concludethat USG infraclavicular block is at least as rapidly executedas USG supraclavicular block and produces a similar degree ofsurgical anesthesia without supplementation.

USG 锁骨下阻滞至少与 USG 锁骨上阻滞一样迅速完成并且产生相似的不需加药的麻醉效果。

No entire nitrendipine crystals were observed visually in SEM photos. The results of X-ray diffraction and differential scanning calorimetry analysis indicated that the crystalline form of nitrendipine was highly dispersed in microspheres, so as amorphous state. The drug release rate of microspheres could be controlled with adjusting the ratio of solid dispersion carriers and retarding agents formulated. The agitation speed and temperature of the preparation process have distinct effect on micromeritic properties of microspheres. The release profiles of the microspheres were mainly affected by the stirring rate of paddle, the concentration of SDS and pH of dissolution medium. Cooling speed and time, however, have no evident influence on the drug release rate of the microspheres. The dissolution data showed that the mechanism of drug release from microsphers was mainly diffusion-controlled. The incorporation efficiencies of 3 batches sample were exceed 96. 8％, which implied that the current method was suitable for design sustained-release dosage form for poorly water-soluble drug.

在扫描电子显微镜下观察，在微球内外未发现尼群地平的完整结晶，X-射线粉末衍射和差示扫描量热试验结果也显示，尼群地平已经被高度分散在微球中；微球的释药速度可通过调整处方中固体分散体载体和阻滞剂的比例控制；制备温度和搅拌速度对微球的质量影响较大；溶出仪的搅拌速度，释放介质的浓度和pH对微球的释放有较大的影响；制备过程中的冷却速度和冷却时间对微球的释放行为影响不很明显；方程拟合的结果表明缓释微球的释药行为符合扩散机制；测定三批微球样品的包封率均在96.8％以上，表明该法适合于制备难溶性药物的缓释微球。

Sensory block, motor block, and supplementation rateswere evaluated for the musculocutaneous, median, radial, andulnar nerves.

感觉阻滞，运动阻滞和添药率评估肌皮神经、正中、桡神经、尺神经等阻滞情况。

JPYFHY Recipe can inhibite the tumor of lung cancer transplanted animals, and the JPYFHY Recipe drug-serum can block the prolife ration of A549/DDP in vitro by inducing cancer cell apoptoses and boking cell cycle; It can enhance the chemotherapy synergism effects when they are used in combination and reverse multidrug resistance which because of DDP. The mechanism of these reversing drug resistance maybe is related to downregulating the expression of MRP and GST and upregulating the expression of TopoⅡ.

健脾益肺化瘀方对动物移植性肺癌具有抑瘤作用，能阻滞肺癌细胞进入增殖期，从而达到抑制肺癌细胞生长的目的；并能增强DDP的敏感性和具有对DDP的耐药逆转作用，其作用机理与健脾益肺化瘀方抑制A549／DDP耐药基因MRP和GST的表达和增强TopoⅡ活性密切相关。

Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) recommends treating most patients with stage 2 hypertension (160/100 mm Hg or higher) with a two-drug combination of a thiazide diuretic plus an ACE inhibitor, angiotensin receptor blocker, beta blocker, or calcium channel blocker.

美国国家联合委员会关于高血压预防、诊断、评估与治疗第七次报告（JNC 7）建议，大多数2期高血压（≥160/100 mm Hg）患者应接受一种噻嗪类利尿剂加一种血管紧张素转换酶抑制剂、血管紧张素受体阻滞剂、β受体阻滞剂或钙通道阻滞剂的两药联合方案治疗。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。