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To study genetic mutations of methylenetetrahydrofolate reductase C677T and cystathioinine-β-synthase T833C related to homocysteine metabolism in patients with ischemic stroke, the MTHFR gene C677T gene mutation and the CBS T833C gene mutation were detected by PCR-RFLP or ARMS method in 74 patients with ischemic stroke and 83 normal people for control. Results showed that the frequencies of MTHFR genet homogenetic type(2.7%), heterogenetic type(51.4%) and T allele(28.4%) in ischemic group were higher than those in control group(1.2%, 39.8% and 21.1%, respectively).

为研究同型半胱氨酸代谢相关酶亚甲基四氢叶酸还原酶基因C677T和胱硫醚-β合成酶基因T833C位点碱基突变与缺血性脑卒中的关系,对74例缺血性脑卒中患者和83例健康对照者,采用聚合酶链反应-限制性片段长度多态性技术检测MTHFR基因C677T基因型,用扩增阻滞突变体系法检测CBS基因T833C突变。

Methods 209 patients with CHD and 101 controls were selected. MTHFR genetic C677T polymorphism was determined by PCR-RFLP, and CBS T833C polymorphism by ARMS method. Plasma homocysteine levels were detected with HPLC. Results The frequencies of MTHFR T homogenetic type and heterogenetic type (27.8%and 45.4%) in case group were higher than those in normal group(22.8%and 34.6%).

对209例冠心病患者和101例健康对照者,采用多聚酶链反应-限制性内切酶片段长度多态性技术检测MTHFRC677T基因型,用扩增阻滞突变体系法检测CBS基因T833C多态性,采用高压液相色谱法测定同型半胱氨酸血浆水平。

Results 5C11 induced homotypic aggregation, proliferation arrest and apoptosis in the multiple myeloma cell line XG2 highly expressed CD40. 5C11 induced B lymphoma cell line Daudi homotypic aggregation and proliferation arrest but no apoptosis.

结果 5C11能引起CD40表达强阳性的多发性骨髓瘤细胞XG2发生同型聚集,抑制其生长并介导细胞凋亡;5C11可引起CD40+的恶性B淋巴瘤细胞株Daudi发生同型聚集,抑制其生长并使细胞发生G2/M期阻滞,但并不介导细胞凋亡。

Results Hypericin of different concentrations could significantly inhibit the proliferation and induce the apoptosis of human prostate cancer cells cultured in vitro.

结果:不同浓度的金丝桃素在体外可显著抑制PC3M细胞增殖(P.05),药物浓度为0.5、1.0和2.0 mg·L-1时,抑制率分别为21%、50%和91%;细胞周期出现S期阻滞,由S期进入M2期的比例为零,并诱导PC3M细胞凋亡。

Objective To compare the efficacy and safety of ropivacaine mesylate CEA and ropivacaine hydrochloride CEA in hypogastric operation.

目的比较甲磺酸罗哌卡因与盐酸罗哌卡因用于下腹部手术硬膜外阻滞的有效性和安全性。

objective :to probe into an effect of ropivacaine complex propofol mainline for sacral canal blocking in hypogastric operation of child.

目的:探讨罗哌卡因小儿骶管阻滞复合异丙酚静注在小儿下腹部手术中应用的效果。

Recently, our study group demonstrated the usefulness of ultrasonographicguidance in ilioinguinal/iliohypogastric nerve blocks in children.

最近我们的研究组已经证实了在小儿髂腹股沟/髂腹下神经阻滞中超声波引导的有效性。

Objective To compare the efficacy and side effects of ilioinguinal/iliohypogastric nerve blockades and rectal paracetamol after pediatric inguinal hernia repair.

目的 观察髂腹股沟/髂腹下神经阻滞与对乙酰氨基酚直肠给药用于小儿疝修补手术后镇痛的效果和安全性。

We conclude that ultrasonographicguidance for ilioinguinal/iliohypogastric nerve blocks in childrenallowed a reduction of the volume of local anesthetic to 0.075mL/kg.

我们得出结论,用于小儿髂腹股沟/髂腹下神经阻滞的超声波引导使局麻药用量减少到0.075mL/kg 。(姜旭晖译,马皓琳李士通校

METHODS: After induction of general anesthesia (1 minimum alveolar anesthetic concentration halothane and laryngeal mask airway), 62 children scheduled for inguinal surgery received an ilioinguinal/iliohypogastric nerve block based on standard anatomical landmarks.

全麻诱导后(1MAC 氟烷和喉罩通气),对62个择期行腹股沟手术的儿童在标准解剖定位下做髂腹下/髂腹股沟神经阻滞

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