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阻断剂

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W-7, an antagonist of calmodulin, also inhibited the effect of ETX by 70%.

钙调蛋白阻断剂W-7亦可使内毒素引起的CGRP释放降低70%。

Rabbits were equipped with intracerebral cannulae directing to two of the four nuclei.

我们在研究吗啡的中枢作用部位时发现,注射微量吗啡到家兔或大鼠的PAG、伏核、杏仁核或缰核内,可产生明显的镇痛作用;而将阿片受体阻断剂纳洛酮注入上述任一核团内,则能大部取消静脉注射吗啡产生的镇痛或电针引起的镇痛。

Two of If inhibitors, ZD7288 and Cs(subscript +), decreased the peak current of I(subscript hHcN2) and their IC50 were 23.9 ± 5.9 μmoL/L,l26.8 ± 27.1 mol/L, respectively. ZD7288 block was not released by washout. The release of Cs(subscript +) block was equally rapid upon switching back to bath solution without Cs .

起搏电流阻断剂ZD7288和Cs灌流,I(下标 hHCN2)峰值幅度均降低,半效抑制浓度分别为23.9±5.9μmol/L、126.8±27.1μmol/L,ZD7288的作用冲洗后抑制作用不能恢复,Cs的作用在冲洗后基本恢复。

Results: Compared with the baseline, REMS was significantly reduced in all groups treated with NBI in a dose-dependent manner, but not with vehicle.

考虑胆碱能系统对睡眠觉醒周期的作用,我们使用阿托品——M_1受体阻断剂,观察其对幼鼠睡眠的影响。

Based on the facts mentioned above, we hypothesize that blockage of CRF R1 receptor will suppress REMS in developing rats.

据此,我们提出这样的问题:使用CRF R1受体阻断剂后,是否会导致发育期大鼠快眼动睡眠减少?

The effect of OFQ on DRG neurones were studied by intracellular microelectrode recording in neonatal Wistar rats.

应用细胞内微电极记录技术,研究初级感觉神经元上是否存在OFQ受体及OFQ对神经元膜电位的影响,并用离子置代及通道阻断剂对其作用机制进行研究。

MedWire News: The angiotensin receptor blocker AR irbesartan does not improve outcomes in well-treated patients with heart failure (HF and a preserved ejection fraction, a major trial has shown.

Medwire新闻:一个主要实验表明,血管紧张素受体阻断剂依贝沙坦不能改善得到良好治疗及射血分数正常的心衰患者的预后。

The excitatory response to intracarotid injection of capsaicin was significantly inhibited by pretreatment with the vanilloid receptor antagonist ruthenium red (200mmol, 0.1ml), The results indicate that capsaicin may activate the neurons of the brainstem nuclei involved in cardiovascular regulation through vanilloid receptors, but does not exert any effects on PAG and RN.

应用辣椒素受体阻断剂钌红(RR; 200mmol, 0.1 ml),可明显抑制辣椒素的上述效应。以上结果提示,辣椒素可通过激活辣椒素受体,引起脑干内多个心血管活动相关核团的神经元兴奋,但对PAC和RN无影响。

A Cl channel in the basolateral membrane of rat parietal cell [J].

氯通道阻断剂对豚鼠离体气管条收缩的影响[J]。

Allocation was by block randomisation stratified by centre and presence or absence of beta-blocker therapy, and all patients and investigators were masked to assignment.

通过研究中心和使用或不使用β-阻断剂进行分层,患者被随机分配,治疗所有患者和研究者均不知道分配方式。

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