阻断

Chelerythrine (20 μM), a potent selective PKC inhibitor, also blocked the facilitation of NMDA/glycine-induce currents by sar-SP.

蛋白激酶广谱拮抗剂H-7（5 μM）有效地阻断sar-SP对NMDA／glycine诱发电流的加强作用；同样地，PKC选择性拮抗剂chelerythrine（50 μM）也完全阻断这一易化作用。

It helps in blocking the nervous impulse due to presence of cholinergic blocking .

它有助于在阻断神经冲动，由于在场的胆碱能阻断。

Yesterday, in Qushan, a stricken area, Wen Jiabao told Hong Kong reporters,"It is possible to move a mountain, but not to shake the Chinese people's determination to carry out relief work. It is possible to stop a river, but not to repress the compatriotic love Hongkongers and mainlanders have for one another."

温家宝昨日在曲山镇赈灾现场接受香港记者访问时说：「山可以移动，但动摇不了广大人民抗震救灾的决心；水可以阻断，但阻断不了香港和内地的同胞之情。

Our results have shown that the analgesic effect of morphine administered to nucleus accumbens was blocked by intra-habenula injection of naloxone or ME antiserum, whereas the analgesic effect of morphine injected into habenula was attenuated by intra-PAG administration of naloxone or muscimol, and enhanced by bicuculline methochoride (BMC, an antagonist of GABA receptor).

本工作实验结果表明，在伏核内注射吗啡产生的镇痛作用可被缰核内注射NX或ME抗体所大部阻断，而缰核内注射吗啡产生的镇痛作用又可被PAG内注射NX或γ-氨基丁酸受体激动剂异鹅羔胺所削弱，被GABA受体阻断剂氯甲基荷包牡丹碱所增强。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

Thus, a vanadate inhibitable event , presumably a phosphotyrosine dephosphorylation event, was required for the initiation of differentiation process.

在用DEX，M1X和insulin诱导3T3-L1前脂肪细胞分化过程中，酪氨酸磷酸酯酶专一性抑制剂Vanadate则能有效阻断细胞分化的进程，但这种阻断是有时间限制的。

Seauckthorn juice can be appropriate drinks afer the diluting, which could block the N-nitroso Synthesis and also can block N-dimethylnitrosaminewhich can lead to cancer.The flavone of Seabuckthorn contains coumarin, isocoumarin, furan coumarins, lignin, as well as bitter polyphenols, 5 - serotonin, which are benefited for anti-cancer.

沙棘汁经稀释成宜引用的浓度后，能阻断N-亚硝酸的合成，另外沙棘汁对致癌物N二甲基亚硝胺也有阻断与防护的作用；沙棘黄酮中含有香豆素，异香豆素，呋喃香豆素，苦木素以及多酚类，5-色胺等具有综合抗癌作用的成分。

Robertson and his colleagues discovered that isothiocyanates may block the activity of Akt3 protein, which is overactive in approximately 70% of melanoma tumors and thought to promote tumor growth by preventing cell death.

Robertson和他的同事发现了异硫氰酸盐类可能阻断Akt3蛋白的激活，Akt3蛋白可以激活接近70%的黑色素瘤而且通过阻断细胞死亡来促进肿瘤的生长。

The inhibitory effect of GABA could be blocked by GABAAreceptor antagonist bicuculline bicuculline methiodide and Cl- channel blocker picrotokin.

GABA的抑制效应大部分可被GABAA受体选择性拮抗剂荷苞牡丹碱甲基碘化物和Cl-通道阻断剂印防己毒素所阻断，而单独灌流BMI和PTX对RVLM神经元主要起兴奋作用。

WT5"HZResults [WT5"BZ]Peilan increased the resting tension of longitudinal and cicular muscule of fundus and longitudinal of bodys.atropine and hexamethonium inhibited the effect of peilan Partially.

结果 佩兰增高胃底纵、环行肌条和胃体纵行肌条的张力。阿托品和六烃季胺分别阻断佩兰增高胃底纵、环行肌张力的作用；佩兰增高胃体纵行肌张力的作用可被六烃季胺阻断。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。