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Crystal structural analysis reveals that, because water molecules bond to Cu atoms, the dhbd ligand can only adopt a hydroxyl oxygen atom to bridge two reversed U-shaped subunits into a novel centrosymmetric dual-U-shaped tetranuclear Cu structure. Each U-shaped frame consists of two crystallographically distinct Cu atoms, two dpphen ligands and one coordinated water molecule.

晶体结构分析表明,由于水的配位阻断, 2,3-二羟基丁二酸根仅通过单羟基氧桥联两个U形双核亚单元形成具有一个对称中心的双U形四核结构,其中U型亚单元包含晶体学上不对称的2个Cu原子、1个2,3-二羟基丁二酸根、2个4,7-二苯基-1,10-邻菲咯啉和1个配位H2O分子。

Tetrodotoxin selectively blocks the neuromuscular electrical activity, producing the effect of nondepolarizing curine and leading to failure of the respiratory drive without compromising the respiratory center.

河豚毒选择阻断神经与肌肉的电生理活动,呈非去极化型箭毒碱样作用,致呼吸动力障碍,与呼吸中枢无关,M胆碱能受体阻滞剂阿托品及中枢兴备剂均无明确使用指征,维持有效通气等综合治疗可达到满意疗效。

To protect the gastric and intestind mucous barrier is crucial, it would be helpful in obstructing and alleviate the Systemic Inflammatory Response Syndrome. We have observed that taking low-dose glutamine in early stage of severe pancreantitis didn't aggravate the burden of pancreas, and the intravenous injection of dipeptid glutamine had much better results.

应注意保护重症胰腺炎的胃肠道粘膜屏障功能,这对阻断或减轻全身炎性反应综合症有重要意义,早期少量口服谷氨酰胺是可取的,且未见增加胰腺负担,有条件者静脉给予足量谷氨酰双肽更好。5。

Taxol have been used in clinic therapy of breast cancer. Generally speaking, taxol can accelerate the-assemble of microtubule, stabilize microtubule from its discomposing, make mitosis stagnate at G2/M, sequentially interdict the normal mitosis and proliferation of cells, induce cell apoptosis; Besides, a direct function of taxol on cell signal and gene expression, activations of apoptosis genes and expression of proteins can induce apoptosis.

紫杉醇已应用于乳腺癌的临床治疗,一般认为紫杉醇能增强微管聚合,稳定微管防止解聚,使有丝分裂停滞在G2/M期,从而阻断正常的有丝分裂和细胞增殖;除此之外,紫杉醇可以直接在细胞信号和基因表达上发挥作用,活化多种凋亡相关基因的表达,从而引发细胞凋亡。

The majority of neurons examined (80.90%) were sensitive to ATP (10-5~10-3M), ATP activated an inward currents in a concentration-dependent manner, and IATP were blocked by PPADSpyridoxalphosphate-6-azophenyl-2′,4′-disulfonic acid, an antagonist of the P2X receptor.

结果显示:(1)大部分受检细胞(80.90%)对外加ATP敏感,产生一具有浓度依赖性的内向电流,且该电流可以被P2X受体拮抗剂PPADS所阻断

By "divergently," we usually meant that at MAC the more strongly acting anesthetic enhanced or blocked the in vitro receptor or channel at least twice as much as did the weakly acting anesthetic.

所谓的&歧异作用&,我们通常是指在 MAC 上,那种对体内某特一受体或通道作用强的麻醉药其激动或阻断效应至少是较弱的那种的两倍。

In a study of 14 hemiplegic patients, those who practiced ankle dorsiflexion using the mirror had more recovery of function in the affected limb than those who underwent direct conditioning.

在镜像治疗中,病患在健侧肢的床边放一面镜子,阻断他们对患侧肢的视线,建立两侧肢体都功能正常的假象;研究中的14名偏瘫病患,患侧肢利用镜子练习踝关节背曲的功能恢复比直接练习者佳。

Furthermore, knockdown of Hspa5 rescues ventralized phenotypes induced by overexpression of Bmp2b; on the other hand, dorsalized phenotypes caused by Hspa5 knockdown disappear when Bmp2b mRNA is coinjected. It is likely that involvement of Hspa5 in dorsoventral patterning is associated with Bmp signals.

进一步研究发现,抑制Hspa5的表达能够挽救Bmp2b过量表达所导致的胚胎腹部化,Bmp2b的过量表达可使阻断Hspa5表达所引起的背部化表型减弱,提示Hspa5在胚胎背腹分化方面的作用可能与Bmp信号相关。

METHODS: Rabbit models of autogenous vein graft were generated in both groups. After anaesthesia, a median incision was made at the neck to dissociate external jugular vein and common carotid artery of the left side. Following blood flow was blocked at the upper and down sides of the common carotid artery, blood vessels were transected to collect 4.0-5.0 cm external jugular vein at the left side, and placed among the common carotid artery at the same side after inversion. End-to-end anastomosis was performed using discontinuous ecstrophy.

两组兔均建立自体静脉移植模型,麻醉后颈前正中切口,游离出左侧颈外静脉及颈总动脉,在颈总动脉的上下两端阻断血流后,横断血管,取左侧的颈外静脉4.0~5.0cm,上下倒向后置于同侧颈总动脉之间,采用间断外翻法行端端吻合。

Thus, in the process of chronic eczematous dermatitis, the apoptosis of keratinocyte is not only a turning point, but also a new target of drug screening.

因此,角质形成细胞的凋亡为湿疹性皮炎慢性化的转折点,阻断角质形成细胞的凋亡可以减轻湿疹慢性化进程的发生,从而为湿疹性皮炎的治疗提供了一条新的途径,成为药物筛选的一个新靶点。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。