阵挛

Female, late 20s,tonic clonic seizure.

女性 近30岁强直阵挛癫痫发作

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响，以及长期使用药物对小鼠耐受性的影响；利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验，观察复方酸枣仁油栀子油的催眠作用；利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用；本实验用地西泮进行平行对照实验，并进行了组方设计和实验。

But afore-mentioned case of illness are the fastest the 6 H after art is the slowest 20 H appears cannot sit quietly, companion breaks up to have quiver on eyeball, brothers Xu is moved, slant first, neck rigidity, flesh is clonic, present opisthotonos individually, but nonexistent pathology is reflexed (Ba Bin this base electronegative).

但上述病例最快术后6 h最慢20 h出现不能静坐，眼球上翻伴有震颤，手足徐动，偏头，颈强直，肌阵挛，个别呈现角弓反张，但不存在病理反射。

Results All affected individuals manifested with age-dependent seizures, combined with tremor, dyssynergia cerebellaris myoclonica and pyramidal sign.

结果 T家系患者临床表现为多种形式的癫痫发作、震颤、肌阵挛小脑协调障碍和锥体束征。

Autosomal dominant inherited; epilepsy; tremor; dyssynergia cerebellaris myoclonica; simulate linkage analysis

常染色体显性遗传；癫痫；震颤；肌阵挛小脑协调障碍；模拟连锁分析

objective to explore the reasonable utilization of cephalosporins in chronic renal failure patients with cephalosporin encephalopathy.method we retrospectively analyzed the clinical characteristics of 29 crf patients,who developed encephalopathic syndrome and was treated with cephalosporin.results the encepha1opathic syndrome include (1)mental confusion in 4 cases;(2)unconsciousness in 2 cases;(3)seizure in 23 cases.physical examination did not show signs of cerebral focal injury.computed tomography of the brain in 29 patients did not show acute lesions.the state of neurotoxicity was completely recovered after discontinuation of cephalosporins.conclusion cephalosporins used in conventional doses or reduced doses can cause temporary encephalopathy in patients with crfwhich might due to prolongation of drug half life.

目的 通过研究慢性肾功能衰竭患者抗生素脑病的发病机制和临床特点，探讨头孢菌素在crf患者中的合理应用。方法 29例crf患者在使用常规剂量或减量使用头孢菌素后出现神经精神症状，诊断为抗生素脑病，将其临床资料进行回顾性分析。结果神经精神症状表现多样：(1)精神异常4例，表现为胡言乱语、烦躁不安、睡眠倒错；(2)意识障碍2例，表现为嗜睡、昏睡、神志不清；(3)癫痫样抽搐23例，表现为肌阵挛、全身抽搐、癫痫样发作；部分患者同时出现几组症状。所有患者均无神经系统定位体征，行颅脑ct检查无急性病变。

Diagnoses were either juvenile myoclonic epilepsy (93.4%) or juvenile absence epilepsy (6.6%).

病人诊断分别为青年型肌阵挛性癫痫（93.4%）和少年型失神性癫痫(6.6%)。

These results suggest that levetiracetam is an effective and well-tolerated adjunctive treatment for patients with previously uncontrolled idiopathic generalized epilepsy with myoclonic seizures.

本研究显示左乙拉西坦对于患有特发性全身性癫痫伴肌阵挛性发作未控制的病人是一种有效而又可以耐受良好的辅助治疗。

Background: Currently, there are no published randomized controlled trials evaluating the efficacy and safety of adjunctive antiepileptic therapy in idiopathic generalized epilepsy with myoclonic seizures.

研究背景：最近没有评价辅助抗癫痫疗法对于特发性全身性癫痫伴肌阵挛性发作的效果和安全性的随机对照研究的文章发表。

Methods: This randomized, double-blind, placebo-controlled multicenter trial assessed the efficacy and tolerability of adjunctive treatment with levetiracetam 3,000 mg/day in adolescents (12 years) and adults (65 years) with idiopathic generalized epilepsy, who experienced myoclonic seizures on 8 days during a prospective 8-week baseline period, despite antiepileptic monotherapy.

本研究采用随机、双盲、安慰剂对照的多中心研究方式，评价在患有特发性全身性癫痫，虽抗癫痫治疗，仍在治疗后的8星期基线期内有8天为肌阵挛性发作的青少年（12岁）和成年（65岁）中使用左乙拉西坦3000mg/天作为辅助治疗的效果和耐受性。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。