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Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要:成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。

The fiber-optic DNA biosensor array can be used to detect a specifical gene or detect multi-DNA sequences simultaneously.

这种制备光纤DNA传感器阵列的方法可用于中、低密度的基因芯片的生产。

The expression of 260 genes were detected in all stages of spermatogenic cells.

利用cDNA微阵列技术分析了1176个小鼠已知基因在不同阶段生精细胞以及成熟精子中的表达谱,发现了多个阶段差异表达的基因。

Two vertical rows of linear LED arrays with superposed lens have the function of driving lights.

两个垂直整齐的直线领导阵列叠加镜头有功能灯驾驶。

Multi-channel synchronal sampling system plays an important role in array signal processing system.

多通道同步采集系统是阵列信号处理系统中的重要环节。

In order to get high gain, narrow main lobe and low sub-lobe antenna pattern, we synthetize the array pattern with Chebyshev method and Unconstrained method seperately.

本文分别采用切比雪夫综合方法和闭式综合法,对直线阵和圆环阵进厅综合,以求得到增益相对高、主瓣窄,副瓣电平低的阵列方向图。

Aiming at the deficiency of the conventional electro-hydraulic proportional valves performance,such as response time and response speed,an ultra-high-speed electro-hydraulic proportional valve is proposed,and the structure of an electro-mechanical converter is put forward using eight pieces tegular Halbach magnet array with gaps.

针对常规电液比例阀在响应时间和响应速度等性能上的不足,设计了一种超高速电液比例阀,并且提出了8片瓦型有气隙Halbach磁化阵列型动圈式电-机械转换器。

The LiF thermoluminescent detector arrays were used to measure the spatial distribution in 4π space of ejected hot electron and hard x-ray emission from ultrashort laser-solid target interaction for the first time.

首次使用LiF:热释光探测器阵列进行了超短脉冲激光与固体靶相互作用中发射的超热电子和硬X射线的全空间(4π立体角)分布测量。

In this thesis, cosmic ray flux recored between 1994-2004 is collected and tided. The annual variation of the data is obvious. Meteorological parameters of 1994-2004 are also tidied in the thesis.

本论文收集整理了Tibet AS γ阵列1994-2004年间记录的宇宙线触发率数据,发现这段时间的宇宙线触发率存在明显的年周期变化。

Unfortunately, up to now, there is not a sort of two-dimensional arrays with fine property of tomographic imaging and high photon collection rate.

目前仍没有一种理想的二维阵列既具有较高的量子收集率,又具有良好的层析成像特性。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。