阴道的

The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity with their intended use as drug bioavailability enhancer for the drugs belonging to therapeutic categories such as antimicrobial, antifungal, anti-viral, antitubercular, antileprosy, anti-inflammatory, antiarthritic, cardiovascular, antihistaminics, respiratory distress relieving drugs, immunosuppressants, anti-ulcerogenic, anti-cancer, CNS drugs, corticosteroids, nutraceuticals in compositions to be administered orally/parenterally, topically, inhalations, rectally, vaginally in human beings and/or veterinary conditions.

本发明涉及植物孜然芹中的一种活性级分的分离和制备，进一步的纯化以及它作为化学确定实体的标准化，和它作为治疗类药物的生物利用率增强剂的特定用途，这类药物包括如抗微生物剂、抗真菌剂、抗病毒剂、抗结核药、抗麻风病药、抗炎药、抗关节炎药、心血管类药、抗组胺药、呼吸窘迫缓解药、免疫抑制剂、抗溃疡药、抗癌药、CNS药、皮质甾类药、营养制品，它们以组合物的形式通过口服/肠胃外，局部，吸入直肠，阴道施用于人和/或兽医学病症中。

The results showed that LRK could significantly inhibit the mammary hyperplasia caused by estrin, reduce the content of serum 〓, raise P level, promote the production of DA in hypothalamus and mammary tissue, decrease the release of 5-HT, inhibit the secretion of serum PRL, reduce the sensitivity of mammary tissue to estrin and progestogen, prevent the expression of mammary tissue on PCNA, the effect was equal to triphenylamine oxide, obviously superior to the control group of Ru Zeng Ning.

通过实验研究，建立了具有肾虚肝郁证侯群的乳腺增生病理模型，利用免疫组化技术、图像分析系统、荧光分光光度法、放射免疫法等现代医学研究方法，从病理形态学、医用体视学、神经内分泌学、阴道细胞学等方面，观察了利乳康口服液对模型动物整体状态、乳腺组织病理形态、血清激素、神经递质以及卵巢功能的影响，结果表明利乳康口服液能明显抑制雌激素引起的乳腺组织增生，降低血清E〓含量，升高P水平，促进下丘脑及乳腺组织中DA的产生，减少5-HT释放，抑制血清PRL分泌，降低乳腺组织对雌、孕激素的敏感性，阻止乳腺组织PCNA的表达，其效应与三苯氧胺相当，明显优于乳增宁对照组；另外，利乳康口服液还能缓解模型动物肾虚肝郁证侯群，增加其体重，调节其整体状况，改善模型动物不规则动情周期，减轻其子宫及卵巢的病变，抑制子宫内膜的过度增长，调节卵巢功能，揭示了中药利乳康口服液对神经内分泌和卵巢功能的整体调控作用，以及对本病发生、发展的预防作用

Results Same conservative sites and key catalytic sites existed among SjLDH and LDHs from other species. Similarity of SjLDH compared to CsLDH, TvLDH and HsLDH was 75%, 17%, 58%-60% respectively. Phylogenetic analysis demonstrated that the evolution relation between SjLDH and DmLDH was closer than the relation between SjLDH and CeLDH, the relationship between SjLDH and HsLDH-B,-C was closer than HsLDH-A. Three trans-membrane regions were found, the region of 98aa-106aa in three hydrophilia regions located outside of membrane was inferred as the major antigen epitope. This antigen epitope had significant difference with LDHs from protozoon （ Pf ., Tg ., Tv .） and had 1-3 amino acid residue difference with MmLDH, HsLDH-A,-B,-C, and was the same with CsLDH. One of the key catalytic residues and substrate binding loop were located in this region. Tertiary structure demonstrated that 98aa-106aa was on the surface of the protein and formed a substrate binding loop, other two key catalytic sites were at the position near the loop.

结果 SjLDH与其他物种的同源序列含相同的保守位点及催化活性位点，与华支睾吸虫LDH同源性最高为75％，与阴道毛滴虫LDH同源性最低为17%，与人LDH（HsLDH-A，-B，-C）的同源性为58%~60％； SjLDH与果蝇的进化距离较秀丽隐杆线虫为近，3种人LDH中与HsLDH-B、-C的进化距离较HsLDH-A为近；该蛋白具有3个跨膜区域，3个高亲水性区域，主要的线性表位98aa~106aa位于膜外，与原虫LDH相同区域差异显著，而与其他LDH有1~3个氨基酸的差异，关键催化位点之一及底物丙酮酸结合区域位于该区域，蛋白质同源模建分析表明该区域位于蛋白表面形成环状结构，3个关键催化位点位于该区域或在其附近。

Smooth, the size of the appropriate treatment of head, easy access to the vagina, the vagina will not scratch the epidermis, treatment will be treated Stick gently enter the vagina, can be efficient, rapid infiltration of lesions, effective treatment of a variety of pathogenic micro-organisms the reproductive system caused by gynecological diseases, the active ingredient can promote epithelial cell growth and healing of wound surface, thereby to cure vaginitis, vulvitis, cervicitis, and other gynecological diseases.

使活性氧气体扩散直达病灶，达到最佳治疗效果。每次工作时间为10分钟左右为好。治疗仪的治疗棒非常的精细，能够在您毫无知觉的状态下进入体内，而且在治疗的过程中，绝对不会有不舒适感觉。因此，在治疗时间，您无须紧张，要放松、保持愉悦的心情。在治疗的过程中，一般都会有干涩的感觉，这是因为气体吹动会使阴道和病灶有些干燥，这时候是最佳的治疗时机，请您放心使用。

But in my family also does not have what tool, I look for a cucumber, puts on with the sheath, gently inserted, because before has not tried with is not like this man's penis inserts own body, at that time felt very novelly, as soon as I like this, entered my vagina with the cucumber, he also coordinated my rhythm tandem to trick his penis.

可是我家里又没有什么工具，我就找来一条小黄瓜，用套子套上，轻轻的插了进去，因为以前从来都没有这样试过用不是男人的阴茎插进自己的身体，当时感觉挺新奇的，我就这样，用黄瓜一进一出的着自己的阴道，他也配合我的节奏一前一后的套弄着自己的阴茎。

With stimulation of the high-speed spiral massage on the relative reflexive areas(for example,gonad,pituitary gland,adrenal gland,testicle, prostate gland,ovary and the like),the endocrine system will promote the secretion of gonadotrophin,uch as testosterone and oestradiol.

通过对应的反射区的高速螺旋循环刺激，如对生殖腺、脑垂体、肾上腺、睾丸、前列腺、卵巢等反射区的刺激，可增加人体内分泌系统中的性腺激素如：睾酮、雌二醇的分泌量，对男性前列腺炎、肥大及男、女功能障碍（阳痿、早泄、阴道干涩、无高潮、性冷淡等）均有一定程度的改善，进而可提高夫妻性生活质量、维持家庭的和谐幸福。

Cee-lo, craps, shoot the moon, poulpe orange, docks 'n' daggers, near t'the vagina, lazy maze, scattered teeth, throw the bones, schieen, and three ivory meatballs are, more often than not, de rigueur in today's party world, and to show up with a wallet full of plastic is to opt out of the fun.

塞埃-罗，胡扯，拍摄月亮，poulpe橙，码头''匕首，近吨'阴道，懒惰的迷宫，散落的牙齿，扔的骨头，schieen，3象牙肉丸的，更多的，往往不是平常的今天'派对世界，展示了一套完整的塑料钱包是退出的乐趣。

In this double-blind study, 142 women with high-risk singleton pregnancies received 100 mg progesterone or placebo daily by vaginal suppository. Between 24 and 34 weeks of gestation, all subjects had uterine contraction monitoring with an external tocodynamometer once weekly for 60 minutes.

对早产的高危险孕妇来说，预防性地在阴道使用progesterone可降低子宫收缩的频率，并减少早产的发生，虽然目前我们还不清楚它的作用机转为何，但我们知道它对子宫肌肉层有2种作用：一为藉由抑制细胞质内动情素受体的取代而抑制动情素发挥作用，另一个则是经由它自身的细胞性受体而直接作用在子宫的生合成路径上。

As early as more than two thousand years ago, in ancient Greece, women suffering from hysteria was considered a kind of strange diseases, when doctors think that this is due to uterine bleeding, so that the fingers vagina massage the uterus, it is logical for the treatment hysteria as an essential means, but then people firmly believe that those who abide by the Hippocratic Oath of doctors fingers can not only cure but also innocence.

早在两千多年前，在古希腊癔病被认为是妇女身患的一种怪病，当时的医生认为这是子宫瘀血所致，这样，把手指伸进阴道按摩子宫，就顺理成章地成为治疗癔病的必要方法，而且当时的人坚信那些恪守希波克拉底誓言的医生的手指，不仅能治病而且还是无邪的。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。