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Previous researches indicated that patients of young or premenopausal age, nonspecial type invasive carcinoma, highly malignant histological degree, advanced tumor stage, negative hormone receptor status and without standard adjuvant therapy would increase the recurrent and metastastic risk of breast cancer after surgery.

既往研究表明,年轻或绝经前患者、浸润性非特殊类型癌、组织学分级恶性程度高、肿瘤分期较晚、激素受体阴性、未进行标准的辅助治疗等均是乳腺癌术后复发转移的高危因素。

The reaction of iodide-potassium iodide was negative to evaluate that EGP was nonstarch polysaccharides, ulfate was 11.92%, content of the total polysaccharide was 83%, mainly including 70.13% D-galactose and 17.95% 3,6-anhydro-galactose.

不溶于有机溶剂,碘-碘化钾反应呈阴性,说明提取物为非淀粉性多糖,产率为20%,总硫酸基含量11.92%,总糖含量83%,主要由70.13%的D-半乳糖和17.95%的3,6-内醚半乳糖组成。

How to assess the difficulty and the possibility of pancreatoduodenectomy and to avoid negative laparotomy has been a question that concerns people.

如何在术前评估胰头十二指肠切除的难度和可能性,避免阴性剖腹探查,是当今人们关注的热点。

Methods Routine immunization of BALB/ c mice by a tansfected cell line 293T/ B7-H4 as antigens.Then the immunized spleen was fused with SP2/0,a kind of plasmocytoma cells, and screen the positive clones by FCS with the 293T/B7-H4 as a positive control while 293T/ mock as the negative control.

以高表达人B7-H4分子的基因转染细胞株293T/B7-H4为免疫原,常规免疫BALB/c小鼠,采用B淋巴细胞杂交瘤技术进行细胞融合,并以该基因转染细胞293T/B7-H4作为阳性筛选细胞,以转空质粒的对照细胞293T/Mock作为阴性对照细胞。

We investigated the impact of polysomy 17 on HER-2 testing and studied its clinicopathologic significance in relation to HER2 gene amplification.

该研究的FISH结果显示,44例患者的HER2绝对拷贝数达可疑阳性,但如果结合17号染色体多体因素(HER2/Chr17),这些患者均为HER2阴性。

Positive and Negative Syndrome Scale , Global Assessment of Function Scale , Modified Overt Aggression Scale , Premorbid Schizoid and Schizotypal Trait and Premorbid Social Adjustment were used in assessment of various phenotypes in affected siblings. It was found that there were high similarities of these phenotypes in siblings with schizophrenia. The results suggested that common etiology, whether genetic or environmental factors, might existed in this pattern of family.

本研究采用阳性症状和阴性症状评定量表、功能全面评定量表、外显攻击行为量表、病前社会适应和病前分裂样分裂型特质对同胞患者进行评定,结果显示各种表现型具有较好的一致性,说明同胞对患者间具有相同的遗传、环境性家族致病因素。

Common contaminants include normal skin flora, including coagulase-negative Staphylococcus and Propionibacterium acnes. The presence of the latter-mentioned

常见的污染源包括普通的皮肤菌群,凝固酶阴性葡萄球菌和丙酸菌属痤疮。

Results For single treatment groups,serum drug concentration of chlorpromazine and clozapine were related to age of patients (P<0 05),concentration of clozapine was related to dosage (P=0 01).For combination group,concentration of chlorpromazine was related to dosage (P<0 01),also related to scores of PANSS and general psychopathological symptoms (P=0 01),concentration of clozapine was related to scores of PANSS,negative and general psychopathological symptoms (P<0 05).Multiple linear regression analysis showed that forms and methods of treatment affected concentration of chlorpromazine,age of patients and methods of treatment affected concentration of clozapine.

结果 单用氯丙嗪和采用氯氮平组的血药浓度均与年龄相关(P<0 05),氯氮平血药浓度与剂量线性正相关(P=0 01);在双氯组中的氯丙嗪血药浓度与剂量线性正相关(P<0 01),与PANSS总分及一般精神病理分相关(P=0 01),而氯氮平血药浓度与PANSS总分、阴性量表分及一般精神病理分明显相关(P<0 05);多元回归分析显示,治疗形式和治疗方法影响氯丙嗪血药浓度,年龄和治疗方法影响氯氮平血药浓度。

It is indicated for acute and chronic schizophrenic psychoses and other psychotic conditions with positive and negative symptoms.

适用于急性和慢性精神分裂症以及其它各种精神病性状态明显的阳性症状和阴性症状的治疗。

Results: Of all the semen samples, 8 were HCMV positive, 4 HSV-Ⅱ positive, but none were both HCMV and HSV-Ⅱ positive. HCMV late antigens were positively and HCMV early antigens negatively expressed in the spermatogenic cells of the 8 HCMV positive cases. In the 4 HSV-Ⅱ positive cases, 3 were positively and 1 weakly positively expressed. In the semen of the 12 positive cases were found large numbers of immature spermatogenic cells, with different manifestations of apoptosis, such as chromatin pycnosis, vacuoles, damaged nuclear membrane, and apoptotic bodies, but without virus infection-induced specific morphological alteration.

结果:83例精液样本PCR检测HCMV阳性8例,HSV-Ⅱ阳性4例,未发现2种病毒同时阳性病例。8例HCMV阳性病例ICC标记生精细胞HCMV晚期抗原均见阳性表达,HCMV早期抗原均为阴性表达;4例HSV-Ⅱ阳性病例ICC标记生精细胞3例阳性表达,1例弱阳性。12例病毒阳性病例均发现较多未成熟生精细胞,并有不同程度的核染色质固缩、出现空泡、核膜破损、核崩解、凋亡小体等凋亡现象,但未能找到病毒感染的特异性形态学改变。

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