阴性

Among pathogens , the most common pathogens associated with VAP were Pseudomonas aeruginosa ( 3013 %), Acinetobacter baumanii (1115 %), Klebsiella pneumoniae ( 1017 %), Escherichia coli ( 716 %) and S taphylococcus aureus ( 618 %). Their multiple drug2resistance to antibiotics was serious. Drug sensitivity tests indicated that the GNB had lower drug2 resistance to such antibiotics as imipenem , amikacin , piperacillin/ tazobactam , ceftazidime , cefepime , cefoperazone/sulbactam , ciprofloxacin and ticarcillin/ clavulanate. Polymicrobial pathogens were more isolated in late2onset VAP than in early2onset VAP.

结果 共检出致病菌383 株，革兰阴性细菌占8411 %，其中非发菌占5114 %，肠杆菌科占3216 %，革兰阳性球菌占1218 %，其中MRSA和MRSE 占615 %，真菌占311 %；前5 位致病菌分别为铜绿假单胞菌(3013 %)、鲍氏不动杆菌(1115 %)、肺炎克雷伯菌(1017 %)、大肠埃希菌(716 %)、金黄色葡萄球菌(618 %)等；药敏结果显示这几类菌株的多重耐药现象严重，较为敏感的抗菌药物有亚胺培南/西司他丁、阿米卡星、哌拉西林/他唑巴坦、头孢他啶、头孢吡肟、头孢哌酮/舒巴坦、环丙沙星及替卡西林/克拉维酸等，革兰阳性细菌均对万古霉素敏感；迟发性VAP 的混合培养比例显著高于早发性VAP。

Muscle biopsy is negative for polymyositis.

肌肉活检显示多肌炎测试阴性

We investigated the impact of polysomy 17 on HER-2 testing and studied its clinicopathologic significance in relation to HER2 gene amplification.

该研究的FISH结果显示，44例患者的HER2绝对拷贝数达可疑阳性，但如果结合17号染色体多体因素(HER2/Chr17)，这些患者均为HER2阴性。

On its own, polysomy 17 was not associated with HER-2 overexpression on IHC or increased HER2 mRNA levels by RT-PCR. Moreover, and in contrast with HER2 gene amplification, polysomy 17 was not associated with high tumor grade, hormone receptor negativity, or reduced disease-free survival.Conclusion: Polysomy 17 affects HER-2 testing in breast cancer and is a major cause of equivocal results by FISH.

不过，在J Clin Oncol同期配发的一篇述评中，美国波士顿大学医学中心的罗森伯格指出，当务之急不是直接进行这样的研究，而是应该对已有研究的IHC、FISH和有效率数据进行回顾或再分析，以明确是否无HER2扩增的17号染色体多体肿瘤被归入不同类别(HER2阴性、阳性)，并由此导致关于HER2靶向治疗疗效的结果不一致。

Results The results turned out to be as follows: The HPV infection positive rate was 45.6%(31/68) for laryngeal carcinoma, 20.0%(3/15) for neck metastatic lymphnode,11.8%(2/17) for precarcinomatous lesions and 6.3%(1/16) for vocal cord polypus. 15 cases of normal tissues adjacent to carcinoma and another 15 normal tissues opposite to the carcinoma were all HPV DNA negative.

结果 喉癌HPV感染阳性率45.6%(31/68)，喉癌颈转移淋巴结组织阳性率20.0%(3/15)，喉癌前病变阳性率11.8%(2/17)，声带息肉阳性率6.3%(1/16)，15例癌旁及15例癌周正常喉组织均为HPV DNA阴性。

By using liposome-mediated gene transfection technology, plasmid pCMVSV40T/PUR containing SV40Tag was transfected in primary embryonic precartilaginous stem cells, while non-transfected cells served as negative controls.

利用脂质体介导基因转染技术将含有SV40Tag的质粒pCMVSV40T/PUR转染原代胚胎前软骨干细胞，以未转染细胞作阴性对照。

Positive and Negative Syndrome Scale , Global Assessment of Function Scale , Modified Overt Aggression Scale , Premorbid Schizoid and Schizotypal Trait and Premorbid Social Adjustment were used in assessment of various phenotypes in affected siblings. It was found that there were high similarities of these phenotypes in siblings with schizophrenia. The results suggested that common etiology, whether genetic or environmental factors, might existed in this pattern of family.

本研究采用阳性症状和阴性症状评定量表、功能全面评定量表、外显攻击行为量表、病前社会适应和病前分裂样分裂型特质对同胞患者进行评定，结果显示各种表现型具有较好的一致性，说明同胞对患者间具有相同的遗传、环境性家族致病因素。

A: A single negative stool examination does not exclude a parasitic infection, since the sample may have been collected during the prepatent period (i.e., the time between infection and the production of detectable ova or larvae) or because the target organism may have been shed inconsistently or in low numbers, as is frequently the case with strongyloides larvae.

一次大便虫卵和寄生虫检查的阴性结果不能排除寄生虫感染，因为样本可能在潜伏期还暂时没有异常（如在感染和产生可以检测到的虫卵或幼体前）或者所关注的微生物已经排出，或者数量太少，如类圆线虫属。

Although the authors found the positive predictive value of concordant pain reproduction to be 85%, the negative predictive value was only 43%, leading them to conclude that provocative facet arthrography was of little value as a presurgical screening tool.

作者发现疼痛复发相关的阳性预测率为85%，阴性预测率仅为43%，他们认为小关节刺激性症状阳性在术前筛选病人方面价值极低。

Objective: Presymptomatic gene diagnosis of autosomal dominant polycystic kidney disease families by PCR Methods: Genomic DNA were extracted Highly polymorphic microsatellite markers(SM7, AG2 5, KG8, CW2) linked to the PKD1were amplified using PCR Ten ADPKD families (104 members,including 28 affected) were analysed Results: Nine children were diagnosed with presymptomatic gene diagnosis ,although all children presented a negative ultrasonic diagnosis Conclusion: The presymptomatic gene diagnosis ...

目的：应用PCR方法对常染色体显性遗传性多囊肾病家系进行症前基因诊断。方法：用PCR扩增与PKD1位点连锁的的高度多态性的微小卫星体DNA（SM7，AC2.5，KG8，CW2）为遗传标记，对10个ADPKD家系的104个成员（包括28个患者）找出染色体上与疾病连锁的单体型，进行连锁分析。结果：对9个无临床症状，且B超检查呈阴性结果的儿童做出了症前基因诊断。结论：能够应用PCR方法对ADP－KD家系成员快速、准确地做出基因诊断

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐