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Objective To study the diagnostic value of adenosine deaminasein all kinds of the pa-tients with liver disease.Methods 212patients of hepatitis in our hospital were selected,135cases were male,and75were female,the average age was(39.6±5.2)years old,in other hand,100blood donors were selected as con-trol group,the value of ADA and the conventional item such as GGT,ALT were determining and a contradistinctive analysis were conducted.Results The item of ADA and the conventional item such as GGT,ALTwere not different in the patients of different kind of liver disease,especially in the patients of chronic persistent hepatitis and chronic active hepatitis,the value of positive rate were92.0%and28.9%,respectively.

目的 测定各类型肝脏疾病病人血清腺苷脱氨酶(adenosine deaminase,ADA)活性值,分析ADA测定结果在各种肝脏疾病中的不同变化,评价ADA测定在肝脏疾病诊断中的应用价值;方法以在我院感染科住院肝炎病人共212例为检测对象,其中男性135例,女性75例,平均年龄(39.6±5.2)岁,以献血员100例为正常对照,对其ADA测定结果进行统计分析,并与传统肝功能检测项目做对比研究;结果 ADA和传统肝功能检测指标在不同类型肝脏疾病中测定值和阳性率各有所不同,特别在慢性活动性肝炎、慢性迁延性肝炎中的阳性检出率有显著不同,分别为92.0%和28.9%,有显著差异(P.01)。

Compared for false masculine and false negatire result in urine analyse;and we have analysed factor of affect as crystal and mucilage and druggery. The result of urine analyzer and the result of microscope have adminicled one another and confirmed one another,both they have different factor of affect. We have collated them and combined clinic symptom, educed correct conclusion.

摘要]对尿液分析中所出现的假阳性,假阴性结果进行了分析比较,对影响尿液测定的结晶,黏液丝,药物等理化因素进行分析,对尿分析仪结果,显微镜检结果之间的相互补充,相互印证,又各自有不同的影响因素,对其进行对照分析,再结合临床症状,得出正确结论。

Prior studies have shown that the consequences of disclosing HIV-positive status may include rejection, abandonment, ostracism and degradation.

此前进行的多项研究结果显示,将HIV检测结果呈阳性的信息告知他人的举动可能会带来包括被人们拒绝、排斥、抛弃以及羞辱等在内的多种负面结果。

The result of uroscopy of the proband was strong positive. There was a novel deletion mutation of c.876-877 del TC in the coding region of exon 6 of IDS gene, which was a hemizygous mutation. However, the mutation of his mother and sister was a heterozygous mutation. Detection of the exon 6 of IDS gene showed that the mutation was not found among normal controls and other patients with MPS I, IV, and VI other than MPS II. Homology comparison of amino acid sequences from different species showed that the phenylalanine glutamine of the mutation site of c.876-877 del TC located in p.292-293 was highly conserved. The activity of IDS enzyme of the proband was only 2.3 nmol/4 h/mL, which was much lower than normal; but the activity of IDS enzyme of his father, mother and sister was 641.9 nmol/4 h/mL, 95.8 nmol/4h/mL and 103.2 nmol/4h/mL, respectively.

结果显示:先证者尿检呈强阳性;其IDS基因exon 6编码区内存在c.876-877 del TC新缺失突变,为半合子突变,而其母、其姐为杂合突变;正常对照和其他非II型MPS患者的IDS基因exon 6的检测结果均未发现该突变;不同物种氨基酸序列的同源性比对显示: c.876-877 del TC突变所在的位置即p.292-293的苯丙氨酸谷氨酰胺高度保守;酶活性测定的结果显示:先证者的IDS酶活性仅为2.3 nmol/4 h/mL,大大低于正常值,而其父的为641.9 nmol/4 h/mL,其母的血浆酶活性为95.8 nmol/ 4h/mL,其姐的为103.2 nmol/4 h/mL。

Results PML RAR α fusion gene of 8 onsetting APL patients were all positive (4 first occurrence, 4 reoccurence);6 of 20 were positive in APL remission phase,in which proportion ratio of promyelocyte in bone marrow smear were all below 5%; a new t...

结果 :发病期的 8例APL患者(初发 4例、复发 4例)PML RARα融合基因均阳性;缓解期APL患者的 2 0人次检查中 6人次阳性,而其骨髓涂片早幼粒细胞比率均小于 5 %;发现一种新的S型变异易位,并见L、S型同时存在于同一个体。

Results: Both EGF treatment and 50 Hz MF exposure could induce EGFR clustering; however, nystatin pretreatment disrupted this effect.

结果:阳性对照组和50 Hz磁场处理组均能观察到EGFR的聚簇现象;制霉菌素预处理1 h后,细胞膜上脂筏结构被破坏,阳性对照组和磁场处理组中受体聚簇现象基本消失。

Histologically, the seminiferous tubules contained numerous Sertoli cells and more Sertoli-spermatozoa complexes, accompanied by the depletion of Leydig cells with deeply stained nuclei. Mature spermatozoa were stored up in the epididymis, but only a few in the efferent ducts. In the second place was testicular atrophy(32/120; 26.7%). The seminiferous tubules showed moderate to severe inactivity of spermiogenesis with evidence of only spermatogonia, spermatocytes and Sertoli cells. The Leydig cells were obviously decreased in numbers associated with decrease of lipid droplets in their cytoplasms. Testicular hypoplasia was the third disorders(22/120; 18.3%). Only a few spermatogonia and Sertoli cells appeared without any spermiogenesis. The associated changes was decreased in Leydig cells and fibrous hyperplasia in the interstitium.Epididymal stones were sometimes found(12/120; 10%). Grossly, yellowish-white nodules with various sizes and firm in consistency were observed in the epididymis and the front efferent ducts. Microscopically, the epididymal ducts were dilated with voluminous spermatozoa storage, even showed calcification in severe cases. The deposited calcium salts were stained positively by Von Kossa and Alizarin red methods.Amyloidosis was also detected in 10 roosters(8.3%). Eosinophilic, homogeneous, amyloid-like substances were deposited mainly in the testicular interstitium and the periphery of blood vessels. These substances showed positive reaction by Congo red staining. Five roosters(4.2%)had Marek's lesions in the testis, epididymis and peripheral nerves with infiltration of pleomorphic lymphocytes. Only one case showed epithelial necrosis of seminiferous tubules accompanied by fibrous proliferation in the interstitium.

结果发现,在总共搜集的120个病例中,其中因年老所导致的产精力不佳为最多,占38例(31.7%),於镜下可见大量精虫黏附於Sertoli cell的表面,并可见Sertoli cell数量明显增多而Leydig cell明显减少,且其细胞核呈现浓染的现象,而在其副睪中仍可见到成熟精虫蓄留於管腔中,但在其输精管内却只有少量精虫存在;其次为睪丸萎缩,占32例(26.7%),镜下可见中度至重度无造精作用,其生精小管中只见到精母细胞、精原细胞及Sertoli cell存在,但Leydig cell数量明显减少且其细胞质内的脂质也明显减少;睪丸发育不全,占22例(18.3%),於生精小管内只见到精母细胞及少量Sertoli cell存在,不见造精细胞分化,於生精小管间质可见Leydig cell减少并伴随结缔组织增生;副睪结石,占12例(10%),肉眼下可在副睪及输精管前段见到黄白色大小不一的结节,触感坚硬,於镜下可见副睪管扩张并有大量成熟精虫蓄积,严重时可见钙化现象,以Von Kossa及茜素红染色均呈阳性反应;类淀粉沉著症,占10例(8.3%),镜下在睪丸间质及血管周围可见粉红均质样的物质沉积,以刚果红染色成阳性反应;马立克病,占5例(4.2%),镜下可在睪丸、副睪实质及周边神经内均可见到嗜碱性大小不一的淋巴样细胞浸润;睪丸坏死,占1例(0.8%),镜下可见生精小管上皮细胞坏死脱落及间质结缔组织增生。

Results The parietal bone of the 9th-week fetuses was a layer of mesenchyme membrane with positive BMP immunoreactivity. In tile parietal hones of 10th to 36 week fetuses, BMP positive immunoreactivity was found in osteoblasts, newly-born osteocytes and periosteum.

结果 第9 w胎儿顶骨为一片间充质膜,呈BMP阳性反应;第10~36 w胎儿顶骨内BMP阳性反应主要见于成骨细胞、新生骨细胞及骨膜中。

The positive rates of serum cTn I and cTn T were 40%(4 cases respectively)among the diagnosed cases,20%(2 cases)and 10%(1 cases)respectively among the suspected cases.

结果 NMC其他疾病组血清cTnI、T均阴性;VMC组各阳性4例(40%);疑似VMC组分别阳性2例(20%)、1例(10%)。

Results The expression of vEGF and the counts of MVD in tumor tissues from patients receiving T...

结果 TACE后二期切除肝癌组织中VEGF阳性表达率为76 92 %,MVD值为16 7 2 3±6 7 39,一期切除肝癌组织中VEGF阳性表达率为30 %,MVD值为98 81±4 7 31,二者比较差异均显著(P 0 5 )。

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