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Methods Immunohistochemistry was used to detect the expression of VEGFR-3,CD31 and lymphatic marker podoplanin in 46 archival surgical specimens of human NSCLC and 8 pulmonary poroma.

结果Podoplanin显示的LVD与CD31显示的血管密度值、VEGFR-3显示的微管密度值不相关(Spearman相关系数0.23,P=0.61;0.09,P=0.84);VEGFR-3阳性管数与CD31阳性管数相关(系数0.80,P=0.031,P.05)。

In situ hybridization and immunocytochemical studies indicated that treatment with 17beta -estradiol increased the number of aromatase-immunoreactive cells and their immunoreactivities, especially in the preoptic area of the hypothalamus, where the density of the aromatase-immunoreactive cells was 2.6 folds higher than the control group. Results indicated that brain aromatase may be involved in the feminization induced by 17beta -estradiol of the grey mullet.

原位杂交和免疫细胞化学定位表明:雌二醇处理组鲻鱼脑内芳香化酶阳性细胞数量和反应强度均提高,尤其在下丘脑视前区,芳香化酶阳性细胞的分布密度为对照组的2.6倍,说明17beta-雌二醇诱导幼鲻雌性化可能与脑芳香化酶的表达有关。

Although the authors found the positive predictive value of concordant pain reproduction to be 85%, the negative predictive value was only 43%, leading them to conclude that provocative facet arthrography was of little value as a presurgical screening tool.

作者发现疼痛复发相关的阳性预测率为85%,阴性预测率仅为43%,他们认为小关节刺激性症状阳性在术前筛选病人方面价值极低。

The sensitivity, specificity, accuracy, positive prevalue, negative prevalue, positive likelihood ratio and negative likelihood ratio of hc2 for high-risk HPV were 100%, 87. 1%, 87. 3%, 8.8%, 100%, 7.7 and 0. 000 , respectively ; and those of gene chips were 78.6%, 91.1%, 90. 9%, 9.9%, 99.7%, 8.8 and 0. 235 respectively.

HC2法检测高危HPV对高度宫颈上皮内瘤样病变HSIL的灵敏度、特异度、准确性、阳性预测值、阴性预测值、阳性似然比和阴性似然比分别为100ˇ、87ˇ1ˇ、87ˇ3ˇ、8ˇ8ˇ、100ˇ、7ˇ7和0ˇ000ˇHPV分型基因芯片法以上各指标分别为78ˇ6ˇ、91ˇ1ˇ、90ˇ9ˇ、9ˇ9ˇ、99ˇ7ˇ、8ˇ8和0ˇ235。

Methods: Young female mice of Kunming species were randomly divided into the different dosages groups, including control groups, and detecting estrogenic activity by increasing uterus weight; Young female rabbits of New Zealand were randomly divided into the different dosages groups, including control groups, detecting progestational activity by proliferation of rabbit endometrium.

昆明种雌性未成年小白鼠100只随机分为空白对照组、阳性对照组及结合雌激素低、中、高剂量组,采用小鼠子宫增重试验检测各组结合雌激素的活性;新西兰雌性未成年白兔40只随机分为空白对照组、阳性对照组及醋酸甲羟孕酮低、中、高剂量组,采用兔子宫内膜转化试验检测各组孕激素的活性。

Results:Serum CYFRA21-1 level was significantly higher in the patients with protopathic breast cancer before operation(the positive rate was 21%)than the patients with benign breast diseases (serum CYFRA21-1 were all negative).

结果:乳腺良性疾病无1例阳性;乳腺癌术前阳性率仅21%,但两者血清 CYFRA21-1 水平有明显差异;47例乳腺癌患者手术前与术后 4周血清 CYFRA21-1 水平相比有显著差异;56例乳腺癌患者术后随访 8例转移复发者中 6例阳性,无转移复发者均阴性,转移复发者血清 CYFRA21-1 水平较无转移复发者明显增高,两者相比差异有极显著性。

Results:Serum CYFRA21-1 level was significantly higher in the patients with protopathic breast cancer before operation(the positive rate was 21%)than the patients with benign breast diseases (serum CYFRA21-1 were all negative).

结果ˇ乳ˇ良性疾病无1例阳性ˇ乳ˇ癌术前阳性率仅21%ˇ但两者血清 CYFRA21-1 水平有明ˇ差异ˇ47例乳ˇ癌患者手术前与术后 4周血清 CYFRA21-1 水平ˇ比有ˇ著差异ˇ56例乳ˇ癌患者术后随访 8例转移复发者中 6例阳性ˇ无转移复发者均阴性ˇ转移复发者血清 CYFRA21-1 水平较无转移复发者明ˇ增高ˇ两者ˇ比差异有极ˇ著性。

Three hundreds of five hundred fertilized eggs microinjected were transplanted into twenty nine pseudopregnant mice.

采取鼠尾,提取基因组。经PCR 检测,阳性鼠 22 只; Southern blotting 检测,阳性鼠 16 只,其中9 只母鼠,7 只公鼠。

Results: At the end of 12 weeks, the efficiencies of both groups were equivalent P<0.05).Compared with pretreatment, the total scores of the PANSS, the Positive, the Negative and the general psychopathological factors were lowered significantly. But the scores of the experiential group were confidential lower than that of control group since the end of 2 weeks. As well as the adverse effects were less and milder. But the dose and fee per day in experience group were smaller than that of control.

结果:治疗12周,研究组和对照组疗效相当;两组PANSS量表总分,阳性量表分,阴性量表分,般精神病理量表分于4周末均较治疗有显著性下降(P<0.01),研究组阳性量表分自第2周起明显优于对照组(P<0.05),且不良反应较少,程度较轻(P<0.05);研究组奥氮平用量较对照组少,经济费用明显偏低。

The COX-2 positive cells were odontoblasts, pulpal fibroblasts vascularendothelial cells and macrophages (positive neutrophils could be found in some cases of the second group and of the third group).(3)We found that COX-2 developed up with HIF-1 a in third group ,but against it infourth group.

COX-2表达阳性的细胞有成牙本质细胞、成纤维细胞、血管内皮细胞和单核巨噬细胞(阳性中性粒细胞可出现在第二组和第三组),HIF-1α与COX-2的表达相关主要在第三组和第四组牙髓标本中体现明显,在第三组二者的变化大致呈平行关系;在第四组基本呈反向变化关系。

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