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Object: To observe the change of IL-6 in serum and CSF ,learning and memory abilities, TUNEL' S apoptosis cells at hippocampus in vascular dementia rats and to probe the relations between the IL-6 and apoptosis, and to investigate the cerebral protection' s mechanism of " yizhiling" which is composed of Polygonum Multiflorum Thunb, Acorus gramineus Soland and Ploygala .

目的:观察血管性痴呆大鼠学习记忆能力,血清及脑脊液中IL-6水平,TUNEL染色阳性细胞在海马神经元的表达,和IL-6与TUNEL染色阳性细胞的关系,探讨&益智灵&脑保护作用机制。

PCNA and MCP-1 expression were both increased in RTEC in ADIN, and the MCP-1 expression in RTEC was correlated with the number of CD68+ cells in renal interstitium. OPN was highly expressed in RTEC in both ADIN and CDIN, its correlation with CD68+ cells infiltration could also be detected.

ADIN中肾小管上皮细胞PCNA及MCP-1表达均增加,后者与CD68阳性细胞数相关(r=0.6771,p.0005);ADIN与CDIN组肾小管上皮细胞均明显表达OPN并与CD68阳性细胞数相关(r=0.5074,p.05)。

Methods A total of 1 147 blood samples were aerobically cultured by BACTEC 9050 in thishospital from Sept.1996 to Mar.1999.The positive rate,false-positive rate,false-negative rate and the time needed to positivity were analysed,respectively.

使用BACTEC 9050全自动血培养仪对1 147例血标本进行需氧培养,分析阳性率、检出菌的种类、阳性检出时间、假阳性和假阴性。

Results Positive rate of Amsel was 28%, one step sialidase was 34%, Gram-stain was 30% and amines was 24%. Using Amsel as criterion, the sensitivity of one step sialidase and amines was 92.9% and 71.4%; specificity was 88.9% and 94.4%; positive predictive value was 76.5% and 83.3% negative predictive value was 97% and 89.5%, using Gram-stain method as criterion, the sensitivity of one step sialidase and amines was 93.8% and 66.7%, specificity was 92.1% and 94.3%, positive predictive value was 83.3% and 83.3%, negative predictive value was 97.2% and 86.8% respectively.

Amsel法阳性率28%,组织多胺试验阳性率24%,一步法唾液酸酶活性的检测试验阳性率34%,革兰染色细菌评分法阳性率30%;唾液酸酶活性检测法与Amsel法,革兰染色细菌评分法相比较差异无显著性;组织多胺试验与Amsel法,革兰染色细菌评分法相比较差异无显著性;以Amsel法为标准,一步法唾液酸酶活性检测法和组织多胺试验的灵敏度分别为92.9%和71.4%,特异性分别为88.9%和94.4%,阳性预期值分别为76.5%和83.3%,阴性预期值分别为97.0%和89.5%;以革兰染色细菌评分法为标准,一步法唾液酸酶活性检测法和组织多胺试验的灵敏度分别为93.8%和66.7%,特异性分别为92.1%和94.3%,阳性预期值都为83.3%,阴性预期值分别为97.2%和86.8%。

Results The small regenerating fibers, central location of nucelus and basophilia endochylema were observed under HE stain both in the patients with DMD and PM. Anachromasis of antiNCAM monoclonal immunohistochemistry stain was found in the regenerating muscle fibers. Positive Ezrin expression was also detected in the regenerating fibers. However, this expression tapered gradually as the mature process of skeletal muscle. The expression of Ezrin was negative in the mature fibers.

结果 DMD、PM患者被检肌HE染色所见再生肌纤维直径较小、核位于中央、胞浆嗜碱性;NCAM染色再生肌纤维深染;再生肌纤维Ezrin呈阳性表达,伴随肌纤维成熟Ezrin表达逐渐减弱,成熟肌纤维无Ezrin表达;成肌细胞Ezrin呈阳性表达。

Fluorescent instruments.the colonies of the specimens yielding growth were identified by the vitek32 instruments and kb method was used for the drug sensitivity tests.results three hundred and thirtyone bacteria strains were isolated from a total of 3104 blood culture specimens,with a positive rate of 10.7%.of the identified bacteria,g+ cocci accounted for 50.3%,g-bacilli accounted for 44.7%,fungi accounted for 3.0%,and anaerobian accounted for 1.1%.the susceptibility rates of g-bacilli to imipenem,amikacin and cefoperazone/sulbactam were high.the susceptibility rate of g+ cocci to vancomycin and imipenem were also high.conclusion g+ cocci prevail over g-bacilli in the blood specimens.the staphylococci are the chief bacteria in the childrens blood specimens.both g+ cocci and g-bacilli are sensitive to imipenem.

结果 在3 104份血液培养标本中分离出病原菌331株,阳性检出率为10.7%。病原菌以革兰阳性需氧球菌居首位(50.3%),革兰阴性需氧杆菌次之(44.7%),真菌占3.0%,厌氧菌占1.1%。血液培养中的g+球菌对万古霉素和亚胺培南较为敏感,g-杆菌对亚胺培南、舒普深、丁胺卡那较为敏感。结论血液培养病原菌以g+球菌为主,g-杆菌次之;儿童血液培养病原菌以葡萄球菌属为主;亚胺培南对g+球菌和g-杆菌均具有较高的敏感率。

To establish anaplasma artificial infection model in experimental animals which treated with dexamethasone to investigate the transmission route of the pathogen, mice were infected via intra-abdominal and subcutaneous inoculation with the blood from infected cattle, the homogenate of infected gadflies and viscera of infected mice, contacting infected mice, respectively, while rabbits were infected through co-feeding with affected cattle.

采用地塞米松注射液长期抑制试验动物的免疫力,通过小鼠腹腔、皮下接种含有无浆体病原的奶牛血液、阳性厩蝇内容物、脏器悬液,并进行阳性小鼠接触感染和兔子临床同层感染等试验,研究奶牛无浆体的感染和传播及在试验动物体内的消长规律,建立起无浆体人工感染模型,调查临床中病原体的实际传播途径。

In the four placebo-controlled studies evaluating radiofrequency denervation outcomes in patients with "confirmed"l-z joint pain, the only study that screened patients with MBB demonstrated positive outcomes,157versus only one of three that used diagnostic intraarticularin jections.158–160 Ultrasound-guided medial branchand intraarticular blocks have also been demonstrated to provide comparable accuracy to fluoroscopically guided injections, although they may be less likely to detect low-volume intravascular uptake and are less accurate in obese patients.161–164 Because MBB are technically easier to perform than intraarticular injections and involve anesthetization of the nerves to be lesioned, it seems more logical to use these blocks as a prognostic tool before radiofrequency denervation.

在四个设有安慰剂对照的对于&确诊&小关节疼痛的患者行射频神经消融后的结果的研究中,唯一一个用MBB筛选研究对象的实验表现出阳性结果,而其他3个用关节内注射筛选的实验中只有1个表现出阳性。超声介导下的内侧支关节囊内阻滞被证实较透视介导更精确,虽然其血管内吸收剂量较低且在肥胖的患者中精确性较差。由于MBB较之关节内注射技术上更简单,且能对受损神经进行麻醉,利用这种阻滞作为神经射频消融前的诊断方法较为合理。

In 2 dogs with suspect MRA diagnosis, one was found positive and one negative by angiograph.

MRA诊断为可疑阳性的2只犬,血管造影证实1只为阳性,另1只为阴性。

The antennal lobes have relatively weak 5-HT immunoreactivity. The antennal mechanosensory and motor centers, in contrast, have relatively strong 5-HT immunoreactivity.

三种蚁型的嗅叶均有较弱的5-HT阳性反应,而背叶具有相对较强的5-HT阳性反应。

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