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The top of neural tube forms basic encenphalic shape,namely endbrain, interbrain, midbrain and afterbrain. The abnormal closure of neural tube will result in neural tube detects. Encephalocoele is a common congenital malformation whose mechanism was no known. NO participates in the physiologic process of brain.

胚胎脑发育的早期阶段主要是神经板隆起、弯曲、闭合形成神经管,神经管的头部从前向后依次发育形成脑的基本组织形态,即端脑、间脑、中脑、后脑,在神经管闭合过程中出现异常就会导致NTD。

PTEN immuno-positive reactive products were extensively distributed in CNS of adult rat, including telencephalon, cerebrum, diencephalon, brainstem, cerebellum, and spinal cord.

PTEN阳性反应产物广泛分布于大鼠的CNS内,包括端脑、大脑、间脑、脑干、小脑和脊髓。

The course will start with an overview of the central and peripheral nervous systems, the development of their structure and major divisions. The major functional components of the CNS will then be reviewed individually. Topography, functional distribution of nerve cell bodies, ascending and descending tracts in the spinal cord. Brainstem organization and functional components, including cranial nerve nuclei, ascending / descending pathways, amine-containing cells, structure and information flow in the cerebellar and vestibular systems. Distribution of the cranial nerves, resolution of their skeletal and branchial arch components. Functional divisions of the Diencephalon and Telencephalon. The course will then continue with how these various CNS pieces and parts work together.

这门课将会从中枢和周边神经系统构造的发展和主要的分化点来概述,中枢神经系统的主要功能将会在复习中个别地说明:神经细胞体的断层以及功能性的分布、脊髓内上升和下降神经束的特征学和功能分布;脑干组织和功能要素,包括脑神经核、上升和下降神经束走向、含胺基酸脑激素细胞的分布、小脑和内耳前庭系统的构造和资讯传导流;颅神经的分布、骨弓和腮弓的演化;间脑和终脑的功能与分类;这门课将会探讨这些不同的中枢神经系统如何一起作用。

Methods The distribution of fos-like immunoreactive neurons in telencephalon, diencephalon, midbrain and pons were examined in 10 "behavioral despair" rats and 10 "simple forced swimming" rats, and the distributions of FLI neurons of the two groups were compared by fos-Ab immunohistochemistry methods.

采用不同强度强迫游泳应激造成绝望行为模型和单纯强迫游泳模型大鼠(Wistar 系雄性,体重160~180 g)各10只,在其端脑、间脑、中脑和脑桥切片上各做抗fos蛋白免疫组化染色,40倍光镜下观察和计数各部位内fos蛋白免疫阳性神经元及其数目,并进行两组之间的比较。

FasL immunopositive neurons were observed in cerebral cortex, especially in pyramidal neurons of lamina Ⅱ and Ⅴ, cerebellar nuclei, diencephalon, and brain stem nuclei involving pontine nucleus, vestibular nucleus, cochlear nucleus, spinal nucleus of trigeminal nerve, hypoglossal nucleus, nucleus ambiguous and reticular formation.

间脑中有FasL阳性神经元分布。在脑干,Fas主要分布于前庭神经核、迷走神经背核和三叉神经脊束核的神经元;FasL广泛分布在脑桥核、前庭神经核、三叉神经脊束核、舌下神经核、蜗神经核、网状结构和疑核。

The most commonly affected region was the mesodiencephalic junction, seen in 30 patients (46%), followed by the pontobulbar region in 26 (40%), the hypothalamic-thalamic region in 15 (23%), the basal ganglia in 12, the telencephalon in five, the cerebellum in three, and the cervical cord in three (Table 1). There was no difference in the distribution of lesions between the acute/subacute or chronic phases.

最常见的受累部位为中脑-间脑接合处(mesodiencephalic junction, MDJ),共在30例(46%)患者中发现此处受累;其次为脑桥延髓区,共在26例(40%)患者中发现此处受累;再次为下丘脑-丘脑区,共在15例(23%)患者中发现此处受累;在12(18%)例患者中发现基底节区受累;5例(8%)患者端脑受累;3例(5%)患者小脑受累;3例(5%)患者颈髓受累(表1)。

Themost common CNS findings reported in these studies, includingours, were a preference for brain stem diencephalic involvementand a tendency to resolve over time.

包括本研究在内的以上各研究均提示:脑干-间脑处是最常见的受累部位,且病灶会随时间推移而逐渐消散。

One view, that episodic memory and semantic memory are both dependent on the integrity of medial temporal lobe and midline diencephalic structures, predicts that amnesic patients with medial temporal lobe/diencephalic damage should be proportionately impaired in both episodic and semantic memory.

一种观点认为,情节记忆和语义记忆都依赖颞叶内部和间脑中线结构,预言颞叶内部、间脑损伤的健忘症病人的情节和语义记忆会相应比例地被削弱。

One view, that episodic memory and semantic memory are both dependent on the integrity of medial temporal lobe and midline diencephalic structures, predicts that amnesic patients with medial temporal lobe/diencephalic damage should be proportionately impaired in both episodic and semantic memory.

一种观点认为,情节记忆和语义记忆都依赖颞叶内部和间脑中线结构,预言颞叶内部、间脑损伤的失忆症病人的情节和语义记忆会相应比例地被削弱。

Objective To approach earlier surgical therapy of hip fracture complicated with cerebral infarction.Methods From 2004 1 to 2005 1, 13 patients suffered hip fracture complicated with internal capsule cerebral infarction, including 5 male and 8 female, mean year is 65.4, all those patients undertook closed replacement internal fixation with hollow nail under X-rays perspection, and early undertook functional exercise.

目的 探讨脑梗死患者股骨颈骨折或股骨粗隆间骨折的早期外科治疗方法自2004年1月~2005年10月对13例内囊区脑梗死出现股骨颈骨折或股骨粗隆间骨折的患者,男5例,女8例,平均年龄65.4岁,全部病例进行X线透视下闭合复位空心钉内固定术治疗,术后早期进行功能训练。

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