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Results There were fetal type in 12 cases, embryonal type in 7 cases, anaplasia type in 3 and mixed type in 2. The cytoplasmic postive expression of CK, AFP, S-100 protein and Vimentin of epithelial tumor cells were found in 14, 10, 9 and 6 cases respectively. Positive staining of CEA, P53 and P16 of nuclei of epithelial tumor cells were found in 11, 9 and 7 cases respectively.Among the 12 cases who underwent surgical excision, 8 patients with fetal type survived over 5 years. Conclusions This study suggests that immunoreaction of hepatoblastomas are different in the histological subtypes.

结果 胎儿型12例,胚胎型7例,间变型3例和上皮间叶混合型2例;细胞角蛋白、甲胎蛋白、S-100蛋白和波形蛋白在肿瘤上皮细胞浆的表达分别为14例、10例、9例和6例,癌胚抗原、P53和P16蛋白在细胞核中的表达分别是11例、9例和7例;手术切除肿瘤12例中8例生存期超过5年者均为胎儿型。

The strong positive expression located in the gland alveolus and duct of serous gland, as well as myoepithelium of mucus glands. In some cases, blood vessel endothelium and fibrous connective tissue also show weakly positive expression of NF-κB.

NF-κB的表达主要见于浆液腺腺泡上皮和导管上皮,呈强阳性表达;黏液腺肌上皮样上皮呈强表达;间质成分中血管内皮呈弱阳性表达、纤维结缔组织呈弱阳性表达。

Here we showed that EMT was inhibited by resveratrol through down-regulating the expression of FOXC2 (forkhead box C2), a critical transcription factor involved in EMT transition.

目前的研究显示上皮-间质转化对多种肿瘤的发展进程具有重要的影响,上皮-间质转化可促近肿瘤细胞的浸润以及肿瘤的转移,在人类以及动物实验中发现上皮-间质转化会导致预后不良。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

In the present study, the expression of bFGF and TGF β1 in normal and hyperplasic prostate were determined with immunohistochemistry and in situ hybridization.

本研究采用免疫组化及原位杂交方法检测bFGF和TGF-β1在正常前列腺及BPH中的表达情况,结果显示,正常及增生前列腺组织中上皮及间质细胞中均见bFGF、bFGFmRNA及TGF-β_1、TGF-β_1mRNA阳性染色,间质细胞染色强于上皮细胞。

Many factors may be involve in the course. To investigate the regulation activity of mesenchymal cells to differentiation of epithelial cells from hair follicle and to study its differentiation property, mesenchymal cells gel was made by nubby dermal papilla cells, free dermal papilla cells, skin fibroblasts. Skin keratinocytes and epithelial cells from hair follicle were inoculated on the gel surface and cultured in air-liquid interface. Three-dimensional model of DPC using to induce epithelial cells differentiation is built in vitro.

为了进一步研究毛囊细胞间的相互作用,探讨毛囊间质细胞对毛囊上皮细胞分化的调节作用,研究毛囊上皮细胞的分化特性,我们利用团块状的毛乳头细胞,游离分散的毛乳头细胞或皮肤成纤维细胞制成间质细胞胶原凝胶,表面接种皮肤角质形成细胞或毛囊上皮细胞,进行气-液界面培养,在体外建立了毛乳头细胞诱导毛囊上皮细胞分化的立体模型。

Result: 1. The situation of HIV infection in gastro-mucosal tissues:(1) Our study found HIV gag sequence in not only CD4~+ T cells but also mucosalepithelial cells, gland epithelial cells in lamina propria and spindle stromal cells;(2) HIV p24 was expressed in T cells, plasmocyte, and a few mucosa epithelial cells, gland epithelial cellls and dell epithelial cellls.

结果:1.HIV在胃黏膜中的感染状况:(1)HIV感染者胃黏膜内HIVgag区基因不仅见于CD4~+T细胞等免疫细胞中,少数胃黏膜上皮、腺上皮、小凹内上皮细胞和间质梭形细胞中亦有阳性杂交信号;(2)HIV感染者尸检胃黏膜内HIVp24蛋白于T细胞、浆细胞及少部分胃黏膜黏膜上皮、腺上皮及小凹上皮细胞中呈阳性表达。2。

Methods The split thickness skin grafts were harvested from avulsed skin by using dermatone of drum type, and the mesh flaps were back grafted for 92 cases with skin avulsion, and 147 cases were treated with back grafted of full-thickness skin grafts.

应用鼓式取皮机反取中厚皮回植治疗92例,反取全厚皮回植治疗147例,对两组病例的回植成活情况进行对照研究。结果在撕脱面积不大时两组间成功率差异不明显,在撕脱皮肤面积较大时,反取中厚皮回植组成功

There is a rare primary liver tumor that has been reported as ossifying stromal-epithelial tumor (3 cases), desmoplastic nested spindle cell tumor (4 cases), and nested stromal-epithelial tumor (6 cases).

肝脏有一种罕见的原发性肿瘤,先前分别有文献将其报道为骨化性间质-上皮肿瘤(3例)、促纤维组织增生性巢状梭形细胞肿瘤(4例)和巢状间质-上皮肿瘤(6例)。

In rat esophagus, the positive varicosities and fibres could be observed in the circular muscle layer and the muscularis mucosae layer at 21st day before birth. With the development of rat digestive tract, neurokinin A-immunoreactivity positive nerves could be observed gradually in the epithelium, submucosa, longitudinal muscle layer, myenteric plexus and submucosal plexes, while mature nerve fibres could be seen at one month after birth. 2. In rat stomach, the positive reaction of NKA initially happened in the myenteric plexus at the 14th day of embryo, and then appeared on circular muscles, longitudinal muscles, submucosal, muscularis mucosae, lamina propria and epithelium. 30 days after birth, expression of NKA is same as seen in adaulthood. 3. In rat small intestinal, the NKA-IR could first be found in the myenteric plexus of the duodenum, jejunum and ileum at 14th , 15th and 17th day before birth respectively. Then the NKA-IR occurred in the longitudinal muscle layer, circular muscle layer, intestinal villus, intestinal gland, muscularis mucosae, submucosa, submucosal plexes, mucosa plexus and deep muscular plexus.

结果 1、在食管,于胚胎21天的粘膜肌层和环肌层内观察到神经激肽A免疫阳性膨体纤维,出生后,随幼鼠的生长发育,相继在上皮,粘膜下层,纵肌层、肌间丛、粘膜下丛有NKA-IR表达,30天时已和成年鼠相似;2、在胃,首先于胚胎14天的肌间丛出现NKA-IR的表达,随发育相继在环肌、纵肌,粘膜下层、粘膜肌、固有膜及上皮内出现NKA-IR的表达,30天时具备成年鼠的分布特征;3、在小肠,分别于胚胎14、15、17天的十二指肠、空肠和回肠的肌间丛处出现NKA-IR的表达,随发育相继出现在纵肌、环肌、绒毛、小肠腺周、粘膜肌、粘膜下层、粘膜下丛、粘膜丛、深肌丛。

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I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里,举止就文雅一些,因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计,这件高贵的制服是香港本土制造,是我们第一套不配帽子的制服。

Do not 'inflate' your achievements and/or qualifications or skills .

不要 '夸大' 你的业绩或成果,条件或者技能。