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This study investigated the mechanisms that induce EMT and the significance of extracellular signal-regulated kinase cascade in this course in vitro.

本文旨在研究酸性成纤维细胞因子对上皮-间质转分化的影响,探讨有丝分裂原激动蛋白激酶的ERK信号传导途径在此过程中的作用,为肾小管-间质纤维化的防治提供理论依据。

Under light microscope, on H-E stain section, four types cells can be distinguish: cells with weak basophilic fibrillar elements; cells with acidophilic granular substance; cells with strong basophilic fibrillar elements and ciliated cells. In the basal lamina region under gland epithelium, there are a few connective tissue; Surface view of the hypobranchial gland could be see by scanning electron microscope, there are cilia and different kinds of secretions distributed. Ultrastructure of the hypobranchial gland could be understand by transmission electron microscope, supporting cells, sensory cells and seven types gland cell were observed to form the glandular epithelium; cells with much rough endoplasmic reticulum,smooth muscle fiber and nerve endings were found beneath glandular epithelium, among basal lamina region.

光镜下H-E染色切片中腺上皮区仅可以区分出四种类型的细胞:弱嗜碱性纤维样细胞、强嗜碱性纤维样细胞、嗜酸性颗粒分泌细胞和纤毛细胞等;腺上皮下的基底膜区有少量结缔组织存在;扫描电镜下可以观察到鳃下腺表面的纤毛及腺细胞的分泌物等情况;透射电镜下观察到腺上皮中有支持细胞、感觉细胞和7种类型的腺细胞;近基底膜区观察到富含粗面内质网的细胞;基底膜间为薄层疏松结缔组织,内含肌细胞及神经末梢等结构。

Decidual tissue is a very complex and highly concordant tiny environment between mother and embryo during pregnancy, which is constituted of the variety cells such as extravi11ous trophoblast,endometrium cells, bone marrow cells, decidua l microphage,T cells and a few B cells and so on.

正常蜕膜组织是母-胎界面间一个非常复杂而又高度协调的微环境,它由多种细胞如侵袭至蜕膜的绒毛外滋养细胞(extravi11ous trophoblast,EVT)、子宫内膜源性细胞(如上皮细胞和血管内皮细胞)、骨髓源性细胞(如大颗粒淋巴细胞、蜕膜巨噬细胞、T细胞和少许B细胞)构成,这些细胞以及由这些细胞、母体和胎儿所分泌到蜕膜的细胞因子共同形成了母-胎间信息交流的平台,并对胚胎滋养细胞"有控性"侵袭、子宫内膜的免疫容受性、蜕膜化和胎盘的形成进行精细的调控。

From the edge of the woods, the white-throated sparrow(which must come all the way from Boston) calls,"Oh, Peabody, Peabody, Peabody!" On an apple bough, the phoebe teeters and wags its tail and says,"Phoebe, phoe-bee!" The song sparrow, who knows how brief and lovely life is, says,"Sweet, sweet, sweet interlude; sweet, sweet, sweet interlude."

在树林的边缘处,白喉麻雀(它们肯定从遥远的波士顿来的)不停的叫:皮博迪,皮博迪;而在苹果树的枝桠间,那东菲比霸王翁摇头摆尾的兀自歌唱:菲比,菲——比;而那知道生命有多短促和甜蜜的歌雀说:甜滋滋,甜滋滋,甜滋滋的插曲,甜滋滋,甜滋滋,甜滋滋的插曲。

Low temperature significantly prolonged fruit storage life,delayed the total sugar,total acid and V_C content loss.Between 2 ℃ and 12 ℃,the lower the storage temperature,the better preservation effect.The best storage temperature of wampee was 2-4 ℃. MAP storage could delay the!quality loss of wampee.0.025 mm polyethylene film with the packing capacity of 5.4 kg·m~(-2) were recommended.

结果表明,常温下黄皮果实贮藏期短,常温贮藏3 d后,好果率低于75%;低温能明显延长果实的贮藏期,延缓果实的糖、酸和VC含量的下降;在2-12 ℃间,贮藏温度越低,保鲜效果越好,适宜的贮藏温度为2-4 ℃;采用MAP保鲜技术能延缓果实品质的下降,在2-4 ℃下大鸡心黄皮MAP保鲜的适宜条件是采用0.025 mm的PE膜包装,装果量为5.4 kg·m-2。

Next, I detected the expression of E-cadherin, an important adhesion molecular mediating the adhesion among epithelia cells.

细胞间的粘附是由粘附分子介导的,E-cadherin是介导上皮细胞间粘附的重要粘附分子,其表达与功能的丧失与多种肿瘤的转移呈负相关。

And more, ERK contents between group A and B, group C and D were not dramatically different. The pathological lesions indicated that intestinal tissue necrosis was severe in group C and D, which were graded 3 points, but obviously lessened in group A and B, which was graded 1 point, with ITF interfering. Conclusion: Intestinal inflammation was ameliorated after ITF was injected hypodermically or intraperitoneally.

结果:A、B组组织匀浆中ERK的面密度值各为87.68±19.24、82.65±21.35,较C、D组(30.23±7.79、30.74±8.19)明显升高(P<0.01),C、D组与E组(5.41±1.46)比较也有升高(P<0.05);并且随著ERK的激活伴随著明显的核转位。A、B组间及C、D组间ERK含量无显著差异(P>0.05);病理切片显示C、D组HE染色切片见肠壁损伤轻重不一,可见全肠粘膜绒毛坏死,病理评分的中位积分为3分;A、B组肠上皮细胞少量脱落,顶端绒毛坏死,病理评分的中位积分为1分。

Results The expression of the Mahoganoid protein and its mRNA was showed by brown staining and observed in the Leydig cells, spermatogonia, primary spermatocytes, spermatids, Sertoli cells, and peritubular myoid cells of testicular tissues and principal cells, basic cells and epithelial cells of epididymal tissues.

结果1。免疫组化法检测Mahoganoid蛋白的实验结果显示的棕色阳性信号可见于各天龄段大鼠睾丸的生精细胞、支持细胞、间质细胞和管周肌样细胞以及附睾输出管的高柱状、低柱状上皮细胞和附睾管的上皮细胞、主细胞、基细胞。其中Mahoganoid蛋白主要表达于胞膜和胞浆。

When there had been balls in the count's house, Pierre, who could not dance, had liked sitting in that little room full of mirrors, watching the ladies in ball-dresses with pearls and diamonds on their bare shoulders, as they crossed that room and looked at themselves in the brightly lighted mirrors that repeated their reflections several times.

伯爵家里举行舞会时,皮埃尔不会跳舞,只喜欢坐在这间嵌有镜子的小客厅里,从一旁观看那些穿着舞衣、裸露的肩上戴有钻石和珍珠项链的女士们穿过这间客厅时照照镜子的情景,几面闪闪发亮的镜子一连几次反映出她们的身影。

Research on Keeping Quality of Different Flesh Types of Prunus persica L.Niu Liang, Wang Zhiqiang, Liu Shu'e, Song YinhuaAbstract: Effects of post-harvest cold storage and Modified Atmosphere Package on fruit hardness, weight losing and soluble solid content of different peach or nectarine varieties were investigated. The results showed that:(1) There were obviously differences of fruit hardness among varieties of different flesh types. In room temperature, FH of '24-30' and 'Zhongtao No.2' went down slower than 'Zhongyoutao No.5' and 'Zhongyoutao No.10'. In cold storage, '24-30', FH of Zongyoutao No.5' and 'Zhongyoutao No.10' descent quickly after 2 weeks of storage while that of 'Shuguang' and 'Zhongtao No.2' quickly descent just after storage.(2) MA package could effectively slow down the decreasing of FH. There were obvious differences among different varieties while 'Zhongyoutao No.10' was less sensitive than others.(3) Soluble solid content went down after harvest and the procedure was slower in lower temperature. In room, MA package seems accelerate the descendent of SSC.

采用不同肉质类型的桃、油桃果实为材料,对采后低温和自发气调包装等对果实硬度、失重和SSC含量等的变化进行了研究,结果表明:(1)不同类型桃、油桃采后果实硬度变化差异较大,常温下24-30和中桃2号果实硬度下降较慢,而中油桃5号、10号较快,在冷库低温条件下,24-30、中油桃5号和中油桃10号两周后硬度出现迅速下降,而曙光和中桃2号在贮藏后即迅速下降,带皮硬度与去皮硬度之间有一定差异,但变化趋势基本一致;(2)MA包装能有效地延缓采后桃、油桃果实硬度的降低,在常温及低温条件下均是如此,不同肉质类型间差异明显,曙光和中桃2号非常敏感,而中油桃10号则不太敏感,即MA包装对其果实硬度降低的延缓没有其它品种明显;(3)采后桃、油桃果实的SSC含量均有一定的降低,低温下该过程较慢,MA包装在常温下有加剧SSC下降的趋势,低温下则不明显,这可能与常温下采后立即进行MA包装不利于&田间热&及呼吸热的及时散发而加剧呼吸有关。

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They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性,但我大喊,并在他们的方向扔石头让他们过的线索,远离我,以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。

Store this product in a sealed, lightproof, dry and cool place.

密封,遮光,置阴凉干燥处。