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Both BM-MSCs and BM-MSCs after directional inducing differentiation in vitro could promote the concrescence of skin wound area of naked mice.

人骨髓间充质干细胞和体外定向诱导分化后的骨髓间充质干细胞对裸鼠的皮肤创面都有促进愈合作用,但在特殊诱导液作用下的骨髓间充质干细胞并没有表现出表皮细胞的功能;并没有出现在上皮化的裸鼠皮肤细胞中。4。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果:1、哇巴因作用于晶状体钠泵后,光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙,电镜下全层细胞空泡化、线粒体肿胀出现髓样结构,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后,光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离,电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后,光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整,电镜下细胞器丰富、细胞功能旺盛,RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后,光镜下晶状体质膜完整、细胞排列紧密规整,电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝,RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后,光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化,电镜下囊侧膜内有高电子密度带、细胞核仁丰富,RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后,光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏,电镜下质膜变性、线粒体肿胀,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

The expressions of E-cadherin and α-catenin in specimens of 54 breast carcinomas and 21 normal breast tissues around tumor were measured by immunohistochemical method. Results In normal breast tissues, E-cadherin and α-catenin were expressed on cell membrance of ductal and acinic cells. No abnormal expressions were found in normal breast tissues. The abnormal expression rates of E-cadherin and α-catenin in breast cancer were 51.9% and 63.0% respectively.

结果 21例癌旁正常组织中,上皮钙黏蛋白和α-连接素均主要定位于腺泡或导管上皮细胞膜上,显示了细胞-细胞间交界和细胞轮廓,二者均表达正常;54例乳腺癌组织中上皮钙黏蛋白和α-连接素的异常表达率分别为51.9%和63.0%。

The results revealed that iontophoresis could significantly improve the penetration of SLN. The fluorescence of images indicated that the accumulation and the depth of QDs-SLN reached in skin increased with times. Anodal delivery of QDs-SLN resulted in a higher accumulation of QDs-SLN in skin than those of cathodal delivery. Furthermore, the vertical images of skin showed that fluorescence assemble in follicle and dermis, indicating that follicle and the junctions between the corneocyte clusters provide the pathway for SLN penetration into skin.

QDs-SLN在皮肤中的滞留量及透皮深度随离子导入时间的增加而增大;正极导入时,QDs-SLN在皮肤深层组织中的含量较高;通过荧光显微镜对垂直于皮肤表面的纵切猪耳全皮中QDs-SLN的分布情况进行考察,结果提示皮肤附属器及角质层中蛋白簇间的结合部位可能为SLN的透皮路径。

This result indicates that WT1 gene plays an important role in differentiation and development of fetal kidney and may be the factor that promotes metanephric blastemal cell to differentiate into epithelial cell.

结果显示小胎龄肾组织中WT1蛋白在胚基细胞和幼稚肾小球细胞核表达而大胎龄组肾组织中WT1在肾小管细胞胞浆表达,阳性率分别为57.1%(8/14)和46.2%(6/13),提示WT1基因在胚胎肾分化发育的过程中起着重要作用,WT1蛋白可能是促进后肾胚基细胞向上皮细胞分化的调控因子,其表达在时间上和空间上都受到严格的调控,WT1的表达异常可能导致胚基细胞分化停滞。17例肾母细胞瘤WT1蛋白表达阳性率为41.2%(7/17),阳性部位在胚基型和上皮型肿瘤细胞核,表达部位和阳性率与早期胚胎肾相似,其中间质型肾母细胞瘤均为阴性,胚基型和上皮型肾母细胞瘤阳性率70%(7/10),两组间阳性率有显著差异。

The result showed that the imbricative cuticle scales arranged irregularly with different distance and irregular orientation. There were overlapping of cuticle cells, smoothing of the zigzag appearance of their edges, local denudation and attached debris.

观察结果表明:矿工头发超微结构的变化主要表现为毛小皮鳞片排列疏密不均,毛小皮间的间距有宽有窄、走向不甚规则;观察到有数个毛小皮细胞相互重叠,游离缘锯齿状变得较为平滑,局部出现片层脱落及在毛干表面附着一些碎片。

The result shows that well developed microbiotic crust results in less invalidation precipitation than sandy soil, but sandy soil conserves 18% precipitation in deeper layer when the soil covered with microbiotic crust had been dry completely.

结果表明,结皮和流沙地表的蒸发速率随时间的变化趋势基本相同,但在不同的蒸发阶段具有各自不同的特点,总的说来,发育良好的苔藓结皮导致相对较少的无效降水,但在更长的时间维持较高的蒸发速率;流沙和初步发育的降尘结皮导致了较多的无效降水,但由于降水的入渗深度相对较深,需要更长的时间完成蒸发过程。

TGF-β1 took on extensive positive in alveolus epithlia in the control group. The positive cytes of the groups under hyperxia-exposure for 3, 7, 14 day distributed in alveolar epithelium, pulmonary interstitial, bronchoepithlia and macrophage, which were notably enhanced along with the time of hyperxia-exposure.

IFN-γmRNA在高氧3天(0.62+0.49)、7天(0.44+0.53)、14天(0.39+0.27 )均高于空气组(0.20+0.14),高氧3天达到高峰水平(P.05),高氧7天后开始下降(P>0.05),高氧14天下降更为明显(P>0.05);TGF-β1的阳性细胞在空气组广泛分布于肺泡上皮,高氧组各期广泛分布于肺泡上皮、肺内间质、支气管上皮、血管内皮和巨噬细胞。

Itplayed a role in the morphogenesis and ductal migration of mammary epithelial cells, promoted theresponsiveness of these cells to lactogenic hormones in vitro and induced the differentiation ofmammary epithelium into secretory lobuloalveoli.

Heregulin-α是细胞间信号蛋白,它可增强体外培养的乳腺上皮细胞对催乳素的敏感性,在乳腺上皮细胞形态发生、导管形成,以及诱导乳腺上皮细胞分化成分泌腺泡中扮演了重要角色,对乳腺发育和乳腺功能调控具有重要作用。

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本公司是一间专业生产汽车用行李架、车顶行李箱、车顶射灯架、玻璃钢纤维、碳纤维、ABS塑料、铝合金定风翼、定风翼刹车灯、备胎架、脚踏板、皮卡车用龙门架、皮卡车用行李箱及PVC皮革、PU环保皮、无纺布、塑料、不锈钢(304#)不锈铁(430#)、玻璃钢纤维、碳纤维等材质备胎罩、汽车扶手箱、汽车用不锈钢铁铲系列产品的专业生产厂家、本公司还有许多产品现正开发中、欢迎世界各地客商来样进行生产、务求做到平、靓、正的原则与世界各地客商达至互惠互利的长期合作伙伴关系。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

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