问题是

The problem of magic square has a long history; furthermore, it is a complicated permutation and combination problem.

幻方问题是具有悠久历史的复杂排列组合问题。

At the same time, the problem of magic square is a typical NP problem, and there are still lots of unresolved puzzle and unfathomed mystery because of the complexity today.

但是，幻方问题是一个典型的 NP 难题，由于问题的复杂性，至今仍有很多未解决的难题和不解之谜。

Traffic is one of the major problems in the city.

交通问题是城市的一个主要问题。

The transportation is one of the major problem in city.

交通问题是城市的一个主要问题。

Therefore, the issue of attentive duty in malpractice crime is essential to solve theoretical and practical difficulties.

因而，医疗事故罪中的注意义务问题是解决该罪理论和实践难题的一个根本性的问题。

This is a question of first importance, Mao wrote.

这个问题是革命的首要问题。

Development is the most important issue in Marxism.

发展问题是马克思主义的最重要的问题。

The relationship between man and nature is a major problem of Marxist view of nature.

人与自然的关系问题是马克思主义自然观中的一个重要问题。

The constrained matrix equation problem is to find the solution of a matrix equation in a constrained matrix set.

约束矩阵方程问题是在满足一定约束条件的矩阵集合中求矩阵方程解的问题。

The truth of the matte r is...

问题的实质在于根本的问题是

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。