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RESULTS: On day 2 after PH, oval cells began to proliferate around the portal area, and matrilin-2 deposition was observed in the hepatic sinusoids in the periportal area. On day 9, proliferating oval cells were present in the hepatic acini, and matrilin-2 upregulation was noted. On day 12, as oval cells differentiated to form hepatocellular nodules, matrilin-2 was distributed mainly in the periphery of the nodules, and little protein was present in the nodules.

结果: 肝脏部分切除术(partial hepatectomy, PH)后第2天,卵圆细胞开始向门静脉周围区域增殖, Matrilin-2主要出现在门静脉周围的肝窦状隙内;术后第9天,卵圆细胞进一步向肝实质内增殖, Matrilin-2表达增加;术后第12天,随着卵圆细胞分化为小肝细胞结节,大多数Matrilin-2位于结节周边,少数出现在结节内。

Objective:To explore the clinical significance of arterial portography in the diagnosis and management of prehepatic type portal hypertension.

目的:探讨间接门静脉造影对诊断肝前型门静脉高压症以及对手术治疗的指导意义。

Results Two kinds of method of prehepatic portal hypertension developed in group B and C, the portal vein pressure increased significantly after nine weeks operating in both group B and group C.

门静脉主干部分结扎附加3周后脾静脉缩窄及其属支结扎的方法建模后门静脉系统的变化符合门静脉高压症的表现,尤其是脾亢状态合适,具有良好的科研应用价值。

Objective The purpose of present study was to evaluate the relative contributions of prostacyclin (PGI2) and the expression of COX mRNA in the hyperdynamic circulatory state of chronic portal hypertensive rats. Methods Twenty male Sprague-Dawley rats were divided into three groups: intrahepatic portal hypertension by injection of CC14, prehepatic portal hypertension by partial stenosis of the portal vein and sham-operated controls.

目的 研究门静脉高压症鼠血浆前列环素(PGI2)水平、血管和小肠中环加氧酶基因表达以及内脏血流动力学的变化,探讨PGI2、COX mRNA表达与门静脉高压症高血流动力学之间的关系。

Results There were slight and remarkable pulsatility in portal vein flow respecti...

结果 正常人门静脉血流频谱随呼吸周期有轻度的波动;三尖瓣返流者门静脉血流的呼吸性变化较正常人显著,且随返流程度的增加而增大,直至出现逆向血流。

Methods Fifteen cases were included in the study, all underwent multi-slice CT and CT portal venography before and after endoscopic variceal ligation. The portal vein and its main bronchi and the twigged veins were depicted and measured.

15例患者在经内镜套扎前、后分别接受门静脉CTA,对门静脉主干、主要属支和侧支循环血管进行显示和测量。

Results and Conclusions The main factors influencing the treatment effect of PHC in China are the followings:(1) Most patients with PHC of subclinical type failed to be diagnosed and treatment in time.(2) As a wrong idea PHC has been considered an "uncurable disease", so the treatment strategy is nagative.(3) Unsuitable choice of treatment resulted in some PHC unable to be resected.(4) Intraoperative massive bleeding due to unskill-operative techniques, increase the postoperative morbidity and mortality.(5) The manner of treatment is not positive for PHC patients with portal cancer thrombosis, bile duct cancer hteombosis and portal hyperlension.(6) Combined therapy can not be used or unsuitably used.

结果与结论影响我国PHC治疗效果的主要因素有:(1)诊断不及时,致使大多数亚临床期病人未及时确诊,丧失了手术良机;(2)观念陈旧,认为肝癌是&不治之症&,治疗态度消极;(3)治疗方法选择不当,使一些本来可以切除的PHC病人错过了手术时机;(4)手术医生技术不熟练,术中出血多,增加了手术后并发症和死亡率;(5)对PHC合并门静脉癌栓,胆管癌栓,门静脉高压症等合并症缺乏积极治疗态度;(6)不重视或不合理应用综合治疗措施等。

Seven cases with portal vein tumor thrombus were diagnosed by CO2-hepatic arterio-sonography (CO2-HAS). Their ultrasonographic features of CO2-HAS were as follows: several seconds after the injection of CO2 microbubble contrast, bright cloudy flowing echoes or several flowing echo stripes along the long axis of portal vein were seen in tumor thrombus. During interrupted phase of CO2 contrast injection there were still scattered unflowing bright echoes in tumor thrombus.

应用二氧化碳(CO2)肝动脉造影诊断 7 例门静脉癌栓,其造影增强声像图表现为:注射CO2微泡造影剂数秒钟后即可见癌栓光团弥漫性光点闪动,似白云翻滚或门脉实体回声内有数条和门静脉管径长轴平行的微气泡光带流动,停止注射后门静脉实体回声内仍有弥漫性非流动性增强光点,持续时间较长。

Seven cases with portal vein tumor thrombus were diagnosed by CO2-hepatic arterio-sonography (CO2-HAS). Their ultrasonographic features of CO2-HAS were as follows: several seconds after the injection of CO2 microbubble contrast, bright cloudy flowing echoes or several flowing echo stripes along the long axis of portal vein were seen in tumor thrombus. During interrupted phase of CO2 contrast injection there were still scattered unflowing bright echoes in tumor thrombus.

中华超声影像学杂志/980401 摘要应用二氧化碳(CO2)肝动脉造影诊断 7 例门静脉癌栓,其造影增强声像图表现为:注射CO2微泡造影剂数秒钟后即可见癌栓光团弥漫性光点闪动,似白云翻滚或门脉实体回声内有数条和门静脉管径长轴平行的微气泡光带流动,停止注射后门静脉实体回声内仍有弥漫性非流动性增强光点,持续时间较长。

Results Segmentalbranchesofpor-tal vein supplied correspondingly hepatic segment,and hepatic vein and its branches located between adjacenthepatic segments. Branches ofportalvein could cross the adjacenthepatic vein. The boundaries ofhepatic seg-mentswere not simple straight lines or flat planes.

结果 门静脉段级分支位于相应的肝段中,而肝静脉及其分支位于相应肝段间,肝静脉相邻各段门静脉分支可跨过肝静脉平面,肝段的分界不是简单的直线或者平面。

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