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Methods A rabbit was celiac-perfused by 5-Fu 100mg/Kg.Then assayed the durg concentrations of janitrix,abdominal aorta,peripheral venous,hydroperitoneum and tissues of liver and kidney by liquid chromatography in specific time;60 cases of hepatocellular carcinoma were radomized into experimental group and placebo group .

实验用家兔腹腔内注入5- Fu 100mg/kg,分别于设定时间抽取门静脉,腹主动脉,外周静脉血,腹腔液,肝、肾组织标本采用高效液相色谱法测定药物浓度;选择中晚期失去手术机会的临床确诊原发性肝癌病人60例,随机分组为实验组(行肝动脉化疗栓塞术中联合腹腔序贯化疗)和对照组(单纯行肝动脉化疗栓塞术)。

Methods:12 patients with hypersplenism due to PH and 4 patients with traumatic rupture of spleen were regarded as hypersplenia and control group respectively. The expressions of TLR2, 4 were detected by real time-PCR.

选取门静脉高压症脾亢患者的手术切除脾脏(12例)为实验组,外伤性脾破裂患者的手术切除脾脏(4例)为正常对照组。

Objective To study the clinical effect and experience of the partial splenicl embolization in the treatment of hypersplenism and portal hypertension.

目的 探讨部分性脾栓塞术治疗门静脉高压性脾功能亢进的临床疗效和初步经验。

Objective To evaluate the portal hemodynamic changes of patients with hypersplenism before and after radiofrequency ablation.

目的探索肝硬化门脉高压性脾功能亢进症在射频消融(radiofrequencyablation,RFA)治疗前后门静脉血流动力学的变化。

Objective To study the security and curative effect of radiofrequency ablationfor hypersplenism due to portal hypertension in the near future.

目的 探讨射频消融治疗门静脉高压性脾大、脾功能亢进症的安全性及近期疗效。

Twenty-one cases of hypersplenism with portal hypertension were treated with partial splenic embolization.

文摘:对21例门静脉高压脾功能亢进患者进行了部分性脾栓塞治疗。

In these cases, angiograms also demonstrate hypervascularity of the lesion.

门静脉阻塞对肝肿瘤及正常肝组织之显影作用都有影响。

Demonstrates hypervascularity within and around the

在肝门部也见到扩张的肝动脉和门静脉

In contrast, the average concentration of 5-FU in the portal vein in animals receiving intraperitoneal injection of 5-FU was 20.67μg/ml 15 minutes after injection and was indetectable 24 hours later.

腹腔化疗组给药后15min门静脉血5-Fu浓度达20.67μg/ml,但持续时间短,24h后浓度极低。

A combination of aorta toinfrarenal aorta anastomosis and portal vein to infrarenal vein cavaanastomosis was adopted for small bowel graft revascularizing.

重建供肠血管采用腹主动脉-肾下腹主动脉吻合以及门静脉-肾下下腔静脉吻合。

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