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We found that 1 mutant EG4 cells showed typical characteristics of pluripotent stem cells which had no obvious difference with wild cells; 2 When induced by 10〓 M retinoic acid , mutant EG4 cells differentiated into adipocytes with high frequency compared with mutant cells, suggested that EGFR plays a role in adipocyte differentiation; 3 when injected into nude mice, mutant teratocarcinomas contained a large amount of connective tissues as well as skeletal muscle, while wild EG4 cells produced frequently cartilage, keratinocyte and neuroepithelium.

我们建立了稳定表达胞内区功能缺失的外源EGFR cDNA片段的EG4细胞,分析其生长分化特性,发现 1)突变型细胞可在未分化状态下维持长时间的增殖,表明EGFR对EG多能干细胞表型无明显影响;2)〓 M的维甲酸A(retinoid acid A,RA)诱导后,大部分对照组细胞分化为脂肪细胞,而突变型细胞分化为脂肪细胞的比例明显较少,表明EGFR在脂肪细胞的发育分化中具有一定的调节作用;3)畸胎瘤切片分析显示,突变型瘤组织分布有大量的未分化细胞和结缔组织,分化细胞以肌肉细胞为主;对照组瘤组织含丰富的角质上皮、软骨、神经管等依赖EGFR的分化组织。

In novative financing in accordance eyes as clear as the functions and instincts of this new perspective, from the heavy learning that cause young people to start the root causes of myopia, myopia prevention and control of relying on long-term perspective can be simply thought the eyes and the fog, as the combined image to combination therapy, adaptive adjustment of the eye, through the 100 days to read and write mirror, looking at nearly two hours to reach the visual axis parallel to the relaxation of the telescope and adjust the state of near vision will be a lot of work transformed into a long look much exercise, not only can enhance distance vision, reducing the degree of myopia, and cleverly solved the telescope and see this contradiction, to make myopic to prevent, control and improve the end, so keep your eyes light up.

开创性地根据双眼融像功能及视清本能这一全新视角,从繁重学习这一造成青少年近视的根源入手,依托望远可以防控近视的朴素思想,将双眼合像法与雾视疗法有机结合,对眼球进行自适应调整,透过百天读写镜,在看近时达到两眼视轴平行和调节放松的望远状态,将大量的视近作业转化成了长时间的望远锻炼,不但可以增强远视力,降低近视程度,并且巧妙地解决了望远与看清这一矛盾,能够使近视患者达到防止、控制、提高的目的,从而让您的眼睛亮起来。

Induced by 4℃ low temperature, Escherichia coli inoculated in water can enter the viable but nonculturable state; in the room temperature, Escherichia coli may keep culturable state for a long period; eutrophic culture media of TSA can produce more bacteria count compared with oligotrophic culture media of PCA; evaluating the bacteria count Escherichia coli in water by plate count method may underestimate the risk of intestinal pathogen contamination.

在4℃低温诱导下,大肠埃希菌在水中可进人活的非可培养状态;在室温下,大肠埃希菌在水中可保持较长时间的可培养性;富营养的TSA琼脂检测的菌落数多于寡营养的PCA琼脂;用平板涂布法检测水中的大肠埃希菌可能低估了肠道致病菌污染的风险。

The pressure to change the direction of your life is strong again this month as the long-lasting opposition between traditional Saturn and progressive Uranus reaches another peak on September 15. The enchanted Pisces Full Moon on September 4 extends your imagination into your everyday life. On September 7, Mercury turns retrograde in your 10th House of Career, reminding you of all the things that haven't worked out according to your plans. Saturn also forms the first of three annoying quincunxes with phantasmagorical Neptune on September 12 to confuse your choices.

9月15日,当传统的土星与积极进取的天王星开始了长时间的相冲时,改变你生活方向的压力在这个月又强烈了起来。9月4日具有魔力的双鱼座满月将你的想象力扩展到了日常生活中。7日,水星开始在掌管你工作的第十宫逆行,提醒着你计划中未完成的所有事件。12日,土星与变幻不定的海王星形成了三大令人讨厌的梅花相位之一来扰乱你的选择。

Thepressure to change the direction of your life is strong again thismonth as the long-lasting opposition between traditional Saturn andprogressive Uranus reaches another peak on September 15. Theenchanted Pisces Full Moon on September 4 extends your imaginationinto your everyday life. On September 7, Mercury turns retrogradein your 10th House of Career, reminding you of all the things thathaven't worked out according to your plans. Saturn also forms thefirst of three annoying quincunxes with phantasmagorical Neptune onSeptember 12 to confuse your choices.

9月15日,当传统的土星与积极进取的天王星开始了长时间的相冲时,改变你生活方向的压力在这个月又强烈了起来。9月4日具有魔力的双鱼座满月将你的想象力扩展到了日常生活中。7日,水星开始在掌管你工作的第十宫逆行,提醒着你计划中未完成的所有事件。12日,土星与变幻不定的海王星形成了三大令人讨厌的梅花相位之一来扰乱你的选择。

The tenet of Vibroseis seismic exploration is outputting as much energy through a continuous bestirring in a period of time as that outputted by other sources in an instantaneous time. The realization of this goal needs that Vibroseis can output a same sweeping signal in many times continuously, then overlap the reflect signal to eliminate the noise from the exploration background, finally visualize the structure of the stratum.

可控震源地震勘探的精髓便是通过系统长时间的持续激励来实现其它震源的瞬时高能量激励,实现这一目标的前提是要求震源系统能够完成相同扫描信号的多次无差别输出,进而通过地震仪进行相应的垂直叠加,充分压制背景噪声,凸现地下的有用构造信息。

It is obligatory to combine the practical circumstances in college English teaching and materialize these reforms by playing the role of coxes, authorizing the outstanding students, participating and cooperating, introducing the competitive mechanism, being propelled by missions and goals, boosting up service consciousness and being driven by market mechanism.

一、发挥舵手作用英语教师的舵手作用是由知识的本质决定的。知识是人类活动经验的总结和积累,是经过很长时间的发展而形成的,是很多人经验的集合。如果完全由学生自己建构,一生恐怕也掌握不了许多。在学习的过程中,需要直接接受别人的经验,离开教师的指导是不行的。

Matsuyama et al used calcium phosphate cement, which polymerizes at lower temperatures.37,38 Results were good in terms of pain relief (8.6 preoperatively and 2 postoperatively on the visual analog scale), neurologic recovery and kyphosis restoration (vertebral height was restored to 68%, compared to 41% preoperatively).37,38 This combination of maximal/minimal surgical treatment has value especially in neurologically compromised patients with indication for surgery, who cannot tolerate long procedures and large blood loss due to medical comorbidities.

Matsuyama等人使用磷酸钙骨水泥,其硬化反应温度较低[37,38],结果表明疼痛缓解良好(视觉模拟评分从术前的8.6分减至术后的2分),神经功能恢复和后凸畸形矫正良好(椎体高度从术前的41%恢复至术后的68 %)[37,38],这个&最大/最小&的手术组合治疗方法,尤其适合伴有神经症状而不能耐受长时间的手术和大量失血的患者。

Research groups of Mayo Medical Center, by long-time tracing and researching, find yips which used to be concluded psychological pressure is now proved to be highly related with physical disorders. Not anxiety, as everybody thought, but "focal dystonia" is the major cause of yips.

美国梅佑医学中心的研究团队,经过长时间的追踪与研究,证实发现以往认为导致高球员推杆失常的现象是心理压力所造成;而最新的研究结果,证明易普的产生,所谓的「局部肌张力不全症」与生理失调有绝大的关联;应为导致高球员产生易普症状的主因,而非一般认为临场的焦虑症。

Fat drippings create smoke that is filled with carcinogenic polycyclic aromatic hydrocarbons, or PAHs. When the smoke envelopes the food, it transfers the PAHs onto the surface of the meat. And when meat, chicken and fish are grilled at high temperatures for long periods of time, compounds inside the food react and create heterocyclic amines, or HCAs. HCAs are worrisome because in lab studies they've been shown to trigger breast, colon and prostate tumors in rats and mice.

滴下来的油脂产生的烟雾充满了致癌的多环芳烃,简称PAHs,当烟雾环绕在食物周围的时候,这些多环芳烃也附着在了食物的表面,当猪肉,鸡肉或是鱼肉在长时间的高温烧烤时,这些食物本身所含有的成分产生了化学变化生成杂环胺类物质,简称HCAs,这类物质相当的麻烦,因为实验室研究发现它们会引起大鼠和小鼠乳腺,结肠以及前列腺部位的肿瘤。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力