镇痛的

To studythe clinical problem that is caused by jingsongling inhibiting the gastric motorfunction in dog and goat,the research through the surgical operation,bipolar Ag-Agcl electrodes are fitted on the surface of serosa in cardia,pylorus,and gastricfundus in dogs,and the surface of serosa in cardic,rumen dorsal sac,reticulum,omasum,abomasum and pylorus in goats,wires are punched through thesubcutaneous of cervical dorsalis.

静松灵是目前国内兽医临床广泛应用的镇静、镇痛药之一，也是均衡麻醉的重要组成成分，为了研究静松灵对单胃和复胃动物胃蠕动的抑制作用所带来的临床问题，本研究通过外科手术方法将Ag-AgCl乏极化电极固定在犬胃的贲门、幽门、和胃底的浆膜上，以及山羊的贲门、瘤胃背囊、网胃体、瓣胃、皱胃和幽门的浆膜上，导线从颈部皮下穿出。

Through consults my courtyard department of pediatrics patient's medical record massively, my courtyard department of pediatrics medication has 4 kind of unreasonable phenomena: 1 antibiotics uses unreasonable; 2 allay a fever the analgesic to have the abusiveness phenomenon; 3 some doctors treat as the trace element and the Vitamin the absolute safety the nutrients; 4 some doctors take 10% glucose inoculation fluid the newborn commonly used basic fluid.

通过大量查阅我院儿科患者的病历，我院儿科用药存在4种不合理的现象：1抗菌药物使用不合理；2 解热镇痛药有滥用的现象；3 有些医师把微量元素及维生素当作绝对安全的营养药；4 有些医师把10%的葡萄糖注射液作为新生儿常用的基本液。

Methods: Adopting pig bile culture medium, the inhibiting or killing effects on pig bladder worm in vitro were observed;by using the methods of xylene-induced ear inflammation in mice and granuloma swelling induced by cotton ball in rats, the effects of anti-inflammation were observed;by using the methods of body twisting and hot-plate in mice, the effects of analgesia were observed. Through the mice auricle microcycle, the rats thrombus law in vitro and bleeding time, clotting time determination to the mice, the function of invigorating the blood were observed;adopting the penicillin abdominal cavity injection method, the mice epilepsy model were prepared, and epilepsy mice brain organization MDA content and SOD, ATPase vigor be measured by using chemical colorimetry.

利用猪胆汁培养基观察该方在体外对猪囊尾蚴的抑制或杀灭作用；采用二甲苯所致小鼠耳肿胀法、大鼠棉球肉芽肿法以观察该方的抗炎作用；采用热板法和化学刺激扭体法观察该方的镇痛效果；通过小鼠耳廓微循环法、大鼠体外血栓法和对小鼠出、凝血时的测定观察该方的活血作用；采用青霉素腹腔注射法制备小鼠癫痫模型，并利用化学比色法检测癫痫小鼠脑组织中MDA的含量及SOD、ATPase的活力。

objective to discuss perioperative complication and management of patient with high risk copd following esophagectomy.methods 45 patients with high risk copd underwent esophagectomy with epidural block combined with general anesthesia.perioperative treatment included smoking cessation,chest physiotherapy,prevention and control of infection of air way and appropriate bronchodilators of air way,breathing exercises,nutrition support and oxygen therapy.painkiller was instilled after surgery,early exercises,ensuring unobstruction of the air way,mechanical ventilation was applied when needed.results 3 had hypoxaemia in operation.after surgery,all patients had spo2 somewhat declined.6 had lung infection.6 were removed of bronchial secretion by bronchoscope.2 were supported by ventilator by using intubation.2 underwent tracheotomy.1 had disturbances of acid base balance and treated by using hydrochloric acid muriatic acid.all patients recovered rather smoothly and discharged from hospital.conclusion high risk copd is not the absolute contraindication of esophagectomy.active management before and after surgery ensures the safety and recovery of patients.

目的 探讨重度慢性阻塞性肺疾病简称慢阻肺病人食管切除术围手术期常见并发症及其处理。方法 45例重度慢阻肺的病人在全麻联合硬膜外阻滞下进行开胸食管切除手术，围手术期处理包括术前戒烟、胸部理疗、预防和控制呼吸道感染、解痉化痰、呼吸功能锻炼、营养支持和氧疗；术后硬膜外镇痛、早期锻炼、保持呼吸道通畅，部分病人予以呼吸支持。结果术中3例出现低氧血症。术后所有病人pao2均有不同程度的下降，6例出现肺部感染，6例行纤维支气管镜吸痰，2例通过气管插管给予呼吸机支持，2例行气管切开术，1例酸碱平衡紊乱使用盐酸精氨酸治疗。所有病人均痊愈出院。结论重度慢阻肺病人并非开胸食管切除手术的绝对禁忌证，积极的术前准备和严格的术后管理可减少和控制术后急性发作，有助于确保此类病人的围手术期安全和康复。

Results: diazepam increases the effect of AA.picroloxin and isoniazid reduce it and antagonize the analgesia effect of ACTH; diazepam increases the content of 5-HT in hipocampus,hypothalamus and midbrain;diazepam + ACTH increases,more than AC-TH or diazepam singly,the level of 5-HT in the 3 brain regions; picrotoxin and isoniazid reverse the effect of diazepam and ACTH on the content of 5-HT in the 3 brainsites; potentiation of diazepam on AA is antagonized by naloxone and atropine.

本实验用腹腔注射干扰GABA代谢和影响其受体药物的方法，探讨GABA在ACTH镇痛中的作用并初步观察其可能的机理。材料与方法实验用体重30～50g左右雄性小鼠153只。一，痛闽测定将动物置入改良的特制的铁笼内¨1f12，以恒速增长的电流强度刺激鼠足跖部

Methods: form january 1995 to january 2005, 42 patients with acute respiratory failure (acute respiratory failure group) and 84 random sampling after esophagectomy and cardiectomy were studied. age, sex, smoke index, preoperative respiratory function, preoperative pulmonary and the other complications, hypoproteinemia, the site of anastomosis, duration of operation, postoperative analgesia, postoperative other complications were compared by logistic regression analysis.

将1995年1月～2005年1月期间食管癌、贲门癌术后发生arf的42例患者临床资料，与按1∶2比例随机抽取的同期手术后未发生arf的84例食管癌、贲门癌患者的资料做对照，应用logistic回归分析比较两组患者的年龄、性别、吸烟指数、术前肺功能、术前有无肺部合并症和其它合并症、术前有无低蛋白血症、吻合口位置、手术时间、术后是否镇痛、术后有无其它并发症等与术后发生arf的相关强度，推测可能导致术后arf发生的危险因素。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时，蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数，说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环(来源：5bABd5C论文网www.abclunwen.com)烯醚萜对外周和中枢5-HT含量的影响目的：探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法：动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组，除对照组外，其余各组进行慢性应激实验。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P＜0.05, P＜0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P＜0.05, P＜0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P＜0.05, P＜0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P＜0.05,P＜0.01),thus restrain the occurrence of synovial tissue inflammation.

结果：(1)电针疏密波组能显著减轻踝关节肿胀度(P＜0.05，P＜0.01)，表明电针有明显的抗炎消肿作用；(2)HE染色显示：电针疏密波组可使大鼠关节炎症细胞浸润明显减轻，滑膜细胞增生明显被抑制，肉芽组织增生明显减少；(3)电针密波组能提高实验性大鼠痛阈(P＜0.05，P＜0.01)，降低外周疼痛介质K~+、DA、5-HT的含量(P＜0.05，P＜0.01)，表明电针有明显的镇痛作用；(4)在病变关节局部，电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P＜0.05，P＜0.01)，升高IL-4的含量(P＜0.05，P＜0.01)，并降低关节滑膜内COX-2mRNA的表达(P＜0.05，P＜0.01)，可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P＜0.05，P＜0.01)，从而抑止滑膜组织炎症发生。

The newly formed company in 2007 of non-tumor drug sales force to promote a narcotic analgesic medication surgery atracurium amines, sevoflurane, speed cards and anti-infective drugs such as clarithromycin sustained-release tablets in the hospital market, the rapid volume growth, the company's 2008 profit growth point of the main one.

在2007年非新成立的公司肿瘤药物的销售队伍，促进手术麻醉镇痛药物阿曲库胺，七氟醚，速度卡和抗感染类药物，如克拉霉素持续的医院市场缓释片，快速量的增长，公司2008年利润的主要增长点之一。

The main products are: 1, disposable nasal oxygen tube, connecting tube 2, the use of disposable skin knife 3, the use of disposable endotracheal intubation 4, the use of disposable suction device 5, analgesic pumps 6, all kinds of disposable Medical Product plastic fittings (tube, spatula, amniotic fluid hook, hemostatic forceps, medical÷×, probe, explore mirror, umbilical cord folders, folder catheter, all kinds of Medical Products joints, drainage bag fittings, etc.) 7, a variety of injection molding plastic products production of "Quality First, Customer Satisfaction" for business purposes, drawn up a strict management system, standardized database from raw material to finished product into a set of testing protocols, production grasp the key processes, technology standards and insist requirements, and resolutely put an end to the inflow of substandard goods procedures and to develop the workshop director is responsible for the quality of accountability, to achieve Total Quality Management, so that product quality has been ensured; inspectors at the same time continually improve operational standards and quality, meticulous preparation the inspection work to ensure that qualified factory Products; and perfect after-sale service and feedback management system, continuously enhance customer satisfaction, quality service to customers.

主要产品有：1、一次性使用鼻氧管、连接管 2、一次性使用备皮刀3、一次性使用气管插管 4、一次性使用吸痰器5、镇痛泵 6、各种一次性医用产品塑料配件（试管、压舌板、羊水钩、止血钳、医用镊子、探针、探镜、脐带夹、导管夹、各种医用产品接头、引流袋配件等）7、各种注塑塑胶产品生产等本公司以&质量第一，顾客满意&为企业宗旨，制定了严格的管理制度，规范了从原材料进库到成品出厂的一整套检验规程，生产中抓好关键工序，坚持工艺标准和要求，坚决杜绝不合格品流入下道工序，并制定车间主任负责的质量责任制，做到全员质量管理，使产品质量得到了保证；同时不断提高检验人员的业务水平和素质，一丝不苟作好各项检验工作，确保产品合格出厂；并完善售后服务和信息反馈管理制度，不断增强顾客的满意度，以优质产品服务广大用户。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。