镇痛作用

Among of them, NC (1-13) NH〓, NC (1-5) NH〓 had the equivalent hyperalgesic effects to NC, however, the effects of NC (1-13) NH〓 was lower than that of them. All of them could antagonize the effects of endomorphins -induced analgesia like NC.

其中NC（1-13）NH〓和NC（1-5）NH〓与NC的效果相当，但NC（1-13）NH〓的作用要弱于NC；NC（1-13）NH〓、NC（1-5）NH〓和NC（1-13）NH〓与NC一样可以对抗吗啡、内吗啡肽-1和内吗啡肽-2的镇痛作用。

Intrathecal injection of nonselective opioid antagonist naloxone blocked the OT-induced antinociception in normal rats and in rats with inflammation; intrathecal injecion of naloxone lightly enhanced the OT-induced hyperalgesic effect in rats with ligation during hyperalgesia phase.

在正常和炎症痛大鼠鞘内注射naloxone几乎完全阻断催产素的镇痛作用，在神经损伤性痛大鼠中naloxone轻微增强催产素的痛敏作用。

Oxcarbazepine is a keto analog of carbamazepine and may have similar analgesic properties to CBZ, but studies on its effects in neuropathic pain conditions are rare.

奥卡西平是一种类似卡马西平的酮类，并和 CBZ 有类似的镇痛作用，但对它在神经性疼痛作用方面的研究很少。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P＜0.05, P＜0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P＜0.05, P＜0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P＜0.05, P＜0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P＜0.05,P＜0.01),thus restrain the occurrence of synovial tissue inflammation.

结果：(1)电针疏密波组能显著减轻踝关节肿胀度(P＜0.05，P＜0.01)，表明电针有明显的抗炎消肿作用；(2)HE染色显示：电针疏密波组可使大鼠关节炎症细胞浸润明显减轻，滑膜细胞增生明显被抑制，肉芽组织增生明显减少；(3)电针密波组能提高实验性大鼠痛阈(P＜0.05，P＜0.01)，降低外周疼痛介质K~+、DA、5-HT的含量(P＜0.05，P＜0.01)，表明电针有明显的镇痛作用；(4)在病变关节局部，电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P＜0.05，P＜0.01)，升高IL-4的含量(P＜0.05，P＜0.01)，并降低关节滑膜内COX-2mRNA的表达(P＜0.05，P＜0.01)，可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P＜0.05，P＜0.01)，从而抑止滑膜组织炎症发生。

Shikimic acid is a single compound extracted from anise Chinese medicine, anti-inflammatory, analgesic effect, is the anti-cancer drug intermediates, there are clear anti-thrombosis, can inhibit the arteries and veins Thrombosis and cerebral thrombosis.

莽草酸是从中药八角茴香中提取的一种单体化合物，有抗炎、镇痛作用，是抗癌药物中间体，有明显抗血栓形成作用，可抑制动、静脉血栓及脑血栓形成。

These findings suggest that NC (13-17) may play important roles in pain modulation at supraspinal level in mice and elicits these effects through a novel mechanism independent of the NC receptor and the traditional opioid receptors The bioactivity study of NC related peptide-NST showed that: NST could dose-dependently reverse the effects of NC in antagonizing EMs-induced analgesia; NST itself could increase the MAP and HVBR of rat, and the tension of rabbit isolated aorta muscle strips.

对孤啡肽相关肽—NST的生理活性研究发现，NST可以剂量依赖的拮抗NC对抗内吗啡肽-1和内吗啡肽-2的镇痛作用；NST对NC的降低大鼠平均动脉压作用无显著影响，但其本身可以升高大鼠的平均动脉压，后肢灌流压和离体血管条的张力，在心血管系统方面是一个新的生物活性肽。

Methods The pain threshold of the rat was measured before and after the application of ultrasound medium frequency electrotherapy. The content of met enhephalin and leu enkephalin in the glandula hypophysis and hypothalamus was also measured.

对大鼠经超声中频电作用后的疼痛反应进行定性、定量分析，并通过直线回归方法分析大鼠痛阈值变化与腺垂体、丘脑下部脑啡肽变化的相关性，探讨其镇痛作用机制。

Meanwhile,to observe the effects of weitongliying soft capsule on chemical incentive on mice,on inflammation of granuloma on rats and on ulcer induced by reserpine on mice.

同时观察了&胃痛立应&软胶囊对小鼠化学刺激的镇痛作用，对大鼠肉芽肿的影响以及对小鼠利血平溃疡的作用。

Methods: xylene induced mouse ear edema models and carrageenan induced rat paw edema models were used to study the anti inflammatory effects. hot plate test in mice was used to study the analgesic effects.

用二甲苯致小鼠耳肿胀、角叉菜胶致大鼠足爪肿胀模型，考察南虎凝胶剂的抗炎作用；热板法观察南虎凝胶剂的镇痛作用。

Methods of acetic acid induced writhing and hot plate test in mice were used to study the analgesic effect.RESULT EMP significantly suppressed xylene induced mouse ear edema and albumin induced rat paw edema.

方法用二甲苯致小鼠耳肿胀、鸡蛋清致大鼠足爪肿胀及大鼠肉芽肿炎症模型，考察绿舒筋多糖的抗炎作用；用小鼠醋酸扭体法和热板法，观察绿舒筋多糖的镇痛作用。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。