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The regulatory elements of the tetracycline resistance operon of Eschenchia coli, Tet repressor and Tet operator, have served as the basis for the establishment of heterologous repression-based inducible system in many eukaryotes including yeast, plants, insects, mammals and parasitic protozoa, such as Trypanosomes, Entamoeba, Giardia, Toxoplasma, Leishmania and Trichomonas.

基于四环素抑制子(Tetracycline Repressor,TetR)和四环素操纵子(Tet Operator,TetO)相互作用的四环素可诱导转基因表达系统,已经广泛的应用于很多真核生物,包括酵母、植物、昆虫、哺乳类细胞和诸如锥虫、阿米巴、贾第虫、弓形虫、利什曼和毛滴虫的寄生原虫。

With a current portfolio of 22 projects, DNDi aims to develop new, improved and field-relevant drugs for neglected diseases, such as malaria, leishmaniasis, Human African trypanosomiasis, and chagas disease.

组织的目标旨在研发创新、改良及适合在资源贫匮地区使用的药物,治疗被忽略疾病,包括疟疾、利什曼病、非洲锥虫病以及南美锥虫病。

Suramin has long been used to treat human trypanosomiasis and onchocerciasis, but since the recent years has received attention as an antitumor drug which has some inhibitory effect on the proliferation ,invasion and metastasis of some malignant tumor cells in vitro and in vivo.

苏拉明是一个用于治疗锥虫和/或盘尾丝虫感染的抗寄生虫药。近些年研究发现苏拉明对肿瘤细胞增殖、浸润、转移等有一定的抑制作用。体内外研究证实苏拉明对多种恶性肿瘤有抗肿瘤活性。

BACKGROUND: Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease.

背景:由布氏冈比亚锥虫引起的非洲人类锥虫病是一种致命的疾病。

Protozoa are responsible for diseases such as malaria, amebic dysentery, giardia, leishmaniasis, and trypanosomiasis.

原生动物是类似疟疾、阿米巴痢疾、贾第虫症、黑热病和锥虫病的罪魁祸首。

Protozoa are responsible for diseases such as malaria, amebic dysentery, giardia, leshmaniasis, and trypanosomiasis.

原生动物是类似疟疾,阿米巴痢疾,贾第虫症,黑热病和锥虫病的罪魁祸首。

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial.

硝呋莫司-依氟鸟氨酸为第二阶段的非洲布氏冈比亚锥虫锥虫病的联合治疗:多中心、随机、III期、非劣效试验。

Giardia, leishmaniasis, and trypanosomiasis.

原生动物是类似疟疾、阿米巴痢疾、贾第虫症、黑热病和锥虫病的罪魁祸首。

Object to the increasing numbers of transposable elements in protozoa genome, this review focus on the types and genomic distributions of transposable elements in newly completed genome of protozoa parasite, mainly including Trypanosoma, Leishmania, microsporidia, Amoebozoa.

针对近年来原生动物全基因组序列中大量发现的转座元件,文章着重比较了转座元件在锥虫、利什曼虫、微孢子虫、变形虫和滴虫基因组序列中的存在种类、分布特征及其功能意义。

Any of various parasitic flagellate protozoans of the genus Trypanosoma, transmitted to the vertebrate bloodstream, lymph, and spinal fluid by certain insects and often causing diseases such as sleeping sickness and nagana.

锥体虫锥体虫属中的一种寄生性带鞭毛原生动物;被某些昆虫带入脊椎动物的血液淋巴液和脊髓,可导致嗜眠性脑炎及非洲锥虫病等疾病

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